Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David Luginbuhl"'
Autor:
Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Applicability of CRISPR-Cas9 for in vivo screening has so far been limited. Here the authors characterize tissue specific CRISPR in the Drosophila mushroom body, generating a library of gRNA-harboring plasmids and fly lines for in vivo screening.
Externí odkaz:
https://doaj.org/article/4534af8f317e409e86de3d3b977b94e0
Autor:
Ya-Hui Chou, Chi-Jen Yang, Hao-Wei Huang, Nan-Fu Liou, Michael Raphael Panganiban, David Luginbuhl, Yijie Yin, Istvan Taisz, Liang Liang, Gregory S. X. E. Jefferis, Liqun Luo
Variations in neuronal connectivity occur widely in nervous systems from invertebrates to mammals. Yet, it is unclear how neuronal variability originates, to what extent and at what time scales it exists, and what functional consequences it might car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cb42ee3391d121685384beb8a72db6
Autor:
Hongjie Li, S Shuster, Tongchao Li, Qijing Xie, Ricardo Guajardo, David Luginbuhl, Chuanyun Xu, Liqun Luo, Tanya Svinkina, Steven A. Carr, Namrata D. Udeshi, Alice Y. Ting, D. R. Mani, Shuo Han, Wei Wei, Sayeh Kohani, Jiefu Li
Transcription factors are central commanders specifying cell fate, morphology, and physiology while cell-surface proteins execute these commands through interaction with cellular environment. In developing neurons, it is presumed that transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4ceabb3f52f9e6f8301b362037e66b
https://doi.org/10.21203/rs.3.rs-983283/v1
https://doi.org/10.21203/rs.3.rs-983283/v1
Autor:
Qijing Xie, Bing Wu, Liqun Luo, Hongjie Li, Jiefu Li, Chuanyun Xu, David Luginbuhl, Xin Wang, Alex Ward
Publikováno v:
Proceedings of the National Academy of Sciences. 116:16068-16073
Our understanding of the mechanisms of neural circuit assembly is far from complete. Identification of wiring molecules with novel mechanisms of action will provide insights into how complex and heterogeneous neural circuits assemble during developme
Autor:
Stephen R. Quake, Felix Horns, Jiefu Li, Qijing Xie, Liqun Luo, Hongjie Li, Bing Wu, Tongchao Li, David Luginbuhl
Publikováno v:
SSRN Electronic Journal.
How a neuronal cell type is defined and how this relates to its transcriptome are still open questions. The Drosophila olfactory projection neurons (PNs) are among the best-characterized neuronal types: Different PN classes target dendrites to distin
Autor:
Sha Liu, Olena Riabinina, Elizabeth Marr, David Luginbuhl, Mark N. Wu, Christopher Potter, Liqun Luo
Publikováno v:
Nature methods
The Q system is a repressible binary expression system for transgenic manipulations in living organisms. Through protein engineering and in vivo functional tests, we report here variants of the Q-system transcriptional activator, including QF2, for d
Autor:
Mark A. Holliday, David Luginbuhl
Publikováno v:
SIGCSE
Understanding the execution of an object-oriented program can be a challenge for a student starting a CS1 course. We believe that a type of diagram that we call a memory diagram can aid the student in understanding object-oriented programming and can
Autor:
David Luginbuhl, Mark A. Holliday
Publikováno v:
34th Annual Frontiers in Education, 2004. FIE 2004..
We believe that improved learning by the undergraduate computer science major is intrinsically linked with improving student engagement. We have developed a framework aimed at encouraging student engagement. Most of the individual ideas are not espec
Autor:
G. Knotts, David Luginbuhl
Publikováno v:
33rd Annual Frontiers in Education, 2003. FIE 2003..
We are developing a course on technology and the political process to be offered jointly by the political science and computer science programs at Western Carolina University. The course objective is to understand how the political process has change
Autor:
David Luginbuhl
Publikováno v:
ACM Computing Surveys. 28:47