Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David Lucio"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15367 (2022)
The unexpected dissolution behaviour of amorphous diflunisal-chitosan solid dispersions (kneading method) with respect to the crystalline co-evaporated systems is the starting point of this research. This work is an in-depth study of the diflunisal r
Externí odkaz:
https://doaj.org/article/5a2a99a1b9b649129e0129917e03d008
Publikováno v:
Proceedings of the 39th IAHR World Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbdb15a6b4fbad776c69f4ce70f13da
https://doi.org/10.3850/iahr-39wc252171192022699
https://doi.org/10.3850/iahr-39wc252171192022699
Autor:
Javier Lopez Lara, Alberto Fernandez, David Lucio, Adela Machado, Pedro Luis Rodriguez, Raquel de la Cruz Modino, Gustavo Herrera, Laura Comes, Inigo Losada, Antonio Tomas
Publikováno v:
Proceedings of the 39th IAHR World Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80805a99db6e0403fcdf7fbc85ad332c
https://doi.org/10.3850/iahr-39wc2521711920221032
https://doi.org/10.3850/iahr-39wc2521711920221032
Publikováno v:
Proceedings of the 39th IAHR World Congress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c62bf902cc7a51a1ceaa530cf082e21
https://doi.org/10.3850/iahr-39wc252171192022916
https://doi.org/10.3850/iahr-39wc252171192022916
Autor:
Juan M. Irache, José L. Vizmanos, Yiyan He, Zhongwei Gu, María Cristina Martínez-Ohárriz, Paula Aranaz, David Lucio
Publikováno v:
International Journal of Pharmaceutics. 547:97-105
The aim of this work was to prepare and evaluate cyclodextrins-modified poly(anhydride) nanoparticles to enhance the oral administration of glibenclamide. A conjugate polymer was synthesized by incorporating hydroxypropyl-β-cyclodextrin to the backb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2942d3fee8c558c942e4fd136702209
https://doi.org/10.1016/j.ijpharm.2018.05.064
https://doi.org/10.1016/j.ijpharm.2018.05.064
Autor:
Juan M. Irache, David Lucio, María Cristina Martínez-Ohárriz, Gustavo González-Gaitano, Carlos J González-Navarro, David Navarro-Herrera, Aurel Radulescu
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 163:64-72
This work describes the feasibility of poly(anhydride) nanoparticles as carriers for the oral administration of glibenclamide (GB) as well as the in vivo evaluation of their hypolipidemic effect in a C. elegans model. For this purpose, and in order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb25657c4f33473e9d533febc0afe3e
https://doi.org/10.1016/j.colsurfb.2017.12.038
https://doi.org/10.1016/j.colsurfb.2017.12.038
Autor:
Aurel Radulescu, Gonzalo Jaras, Carlos J González-Navarro, María Cristina Martínez-Ohárriz, Juan M. Irache, David Lucio, Paula Aranaz
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 121:104-112
The aim of this work was to evaluate the capability of zein nanoparticles as oral carriers for glibenclamide (GB). Nanoparticles were prepared by a desolvation procedure in the presence of lysine as stabilizer. A central composite design was used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632d426d4415e744a23eaf68645c84c1
https://doi.org/10.1016/j.ejpb.2017.09.018
https://doi.org/10.1016/j.ejpb.2017.09.018
Publikováno v:
International Journal of Pharmaceutics. 530:377-386
Glibenclamide is an antidiabetic drug showing low bioavailability as consequence of its low solubility. To solve this drawback, the interaction with cyclodextrins has been proposed. The formation of GB-βCDs inclusion complexes was carried out using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abcbb28ef05d4ee5bec7c8d406a5943
https://doi.org/10.1016/j.ijpharm.2017.08.002
https://doi.org/10.1016/j.ijpharm.2017.08.002
Publikováno v:
Philos Trans A Math Phys Eng Sci
Historic coastal structures have played a key role in small- to medium-size ports, being the driving force for the local development of coastal communities. Because coastal managers require reliable risk-based analysis of the whole life cycle of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f99d71de834617786b91b3670b1cc9c
https://europepmc.org/articles/PMC6710466/
https://europepmc.org/articles/PMC6710466/
Publikováno v:
Coastal Engineering. 161:103771
Port development – as key aspect of sustained economic growth – implies large investments in coastal structures, increasing the risk of structural failures and operational stoppages due to coastal hazards. Then, this paper presents a new approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b834fff8a8a2303266c3f742d139d2cd
https://doi.org/10.1016/j.coastaleng.2020.103771
https://doi.org/10.1016/j.coastaleng.2020.103771