Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David Loven"'
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240994 (2020)
Extracellular vesicles (EVs) are subcellular membrane blebs that include exosomes and microparticles, which represent a potential source for cancer biomarker discovery. We assess EVs characteristics as a tool to evaluate the endothelial and anti-tumo
Externí odkaz:
https://doaj.org/article/54edb4aeb23141e8900e82e5bd196a5c
Autor:
Dror Alishekevitz, Svetlana Gingis-Velitski, Orit Kaidar-Person, Lilach Gutter-Kapon, Sandra D. Scherer, Ziv Raviv, Emmanuelle Merquiol, Yael Ben-Nun, Valeria Miller, Chen Rachman-Tzemah, Michael Timaner, Yelena Mumblat, Neta Ilan, David Loven, Dov Hershkovitz, Ronit Satchi-Fainaro, Galia Blum, Jonathan P. Sleeman, Israel Vlodavsky, Yuval Shaked
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1344-1356 (2016)
Summary: While chemotherapy strongly restricts or reverses tumor growth, the response of host tissue to therapy can counteract its anti-tumor activity by promoting tumor re-growth and/or metastases, thus limiting therapeutic efficacy. Here, we show t
Externí odkaz:
https://doaj.org/article/33aac968c8234da399706c8ab64ff755
Autor:
Dvir Shechter, Michal Harel, Abhishek Mukherjee, Leonel M. Sagredo, David Loven, Elad Prinz, Shimrit Avraham, Veronique Orian-Rousseau, Tamar Geiger, Yuval Shaked, Haguy Wolfenson
Publikováno v:
Cells, Vol 9, Iss 10, p 2269 (2020)
Tumor cell heterogeneity is primarily dictated by mutational changes, sometimes leading to clones that undergo a metastatic switch. However, little is known about tumor heterogeneity following chemotherapy perturbation. Here we studied the possible i
Externí odkaz:
https://doaj.org/article/ad1312aa5d2445d9a9d2390480b8e5c2
Autor:
Yuval Shaked, Stefan J. Scherer, Ella Fremder, Svetlana Gingis-Velistki, Tali Voloshin, Valeria Miller, David Loven, Rotem Bril, Dror Alishekevitz
PDF - 5513KB, Supplemental Materials & Methods; Supplemental Table 1: Evaluation of MTD chemotherapy in BALB/c mice; Supplemental Table 2: Analysis of changes in the levels of pro-angiogenic cytokines in plasma of mice treated with FOLFOX chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb818a18ee0a0f7d6340b7ed9bfda7c0
https://doi.org/10.1158/1535-7163.22503279
https://doi.org/10.1158/1535-7163.22503279
Autor:
Yuval Shaked, Francesco Bertolini, Dror Alishekevitz, Tali Voloshin, Rotem Bril, Michal Munster, Liat Benayoun, David Loven, Svetlana Gingis-Velitski
Mounting evidence suggests that bone marrow–derived cells (BMDC) contribute to tumor growth, angiogenesis, and metastasis. In acute reactions to cancer therapy, several types of BMDCs are rapidly mobilized to home tumors. Although this host reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab573f59e22ff044b3120098bfcf428b
https://doi.org/10.1158/0008-5472.c.6503177.v1
https://doi.org/10.1158/0008-5472.c.6503177.v1
Autor:
Yuval Shaked, Francesco Bertolini, Dror Alishekevitz, Tali Voloshin, Rotem Bril, Michal Munster, Liat Benayoun, David Loven, Svetlana Gingis-Velitski
PDF file - 184K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7aff429d0ec83fb7639e2621492b479
https://doi.org/10.1158/0008-5472.22391177
https://doi.org/10.1158/0008-5472.22391177
Autor:
Leonel Munoz Sagredo, Shimrit Avraham, Véronique Orian-Rousseau, Haguy Wolfenson, Abhishek Mukherjee, Tamar Geiger, Dvir Shechter, Yuval Shaked, Michal Harel, Elad Prinz, David Loven
Publikováno v:
Cells
Cells, Vol 9, Iss 2269, p 2269 (2020)
Volume 9
Issue 10
Cells, 9 (10), 2269
Cells, Vol 9, Iss 2269, p 2269 (2020)
Volume 9
Issue 10
Cells, 9 (10), 2269
Tumor cell heterogeneity is primarily dictated by mutational changes, sometimes leading to clones that undergo a metastatic switch. However, little is known about tumor heterogeneity following chemotherapy perturbation. Here we studied the possible i
Autor:
David Loven, Shahar Ben-Shaul, Benjamin Brenner, Hila Berkovich, Gil Bar-Sela, Anni Rebibo Sabbah, Anat Aharon
Publikováno v:
Oncotarget
// Anat Aharon 1, 2 , Anni Sabbah 1 , Shahar Ben-Shaul 1 , Hila Berkovich 1 , David Loven 4 , Benjamin Brenner 1, 2 and Gil Bar-Sela 2, 3 1 Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel 2 Bruce Rap
Autor:
Yuval Shaked, Anat Aharon, Svetlana Gingis-Velitski, David Loven, Michal Munster, Ella Fremder, Benjamin Brenner, Tali Voloshin, Dror Alishekevitz, Valeria Miller, Stefan Scherer, Rotem Bril
Publikováno v:
International Journal of Cancer. 135:270-281
Acute chemotherapy can induce rapid bone-marrow derived pro-angiogenic cell (BMDC) mobilization and tumor homing, contributing to tumor regrowth. To study the contribution of tumor cells to tumor regrowth following therapy, we focused on tumor-derive
Publikováno v:
Drug Discovery Today. 18:193-201
Low-dose metronomic (LDM) chemotherapy represents an emerging concept in the treatment of cancer. Directed against tumor cells and other types of cells, such as endothelial and immune cells, this treatment regimen alters the tumor microenvironment an