Effects of switching from a metered dose inhaler to a dry powder inhaler on climate emissions and asthma control: post-hoc analysis

Autor: Ashley Woodcock, Christer Janson, Jamie Rees, Lucy Frith, Magnus Löfdahl, Alison Moore, Martin Hedberg, David Leather

Publikováno v: Thorax. 77:1187-1192

ObjectiveTo compare the effects of switching from a pressurised metered dose inhaler (pMDI)-based to a dry powder inhaler (DPI)-based maintenance therapy versus continued usual care on greenhouse gas emissions (carbon dioxide equivalents, CO2e) and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a63357813bd64190f796889864ea134
https://doi.org/10.1136/thoraxjnl-2021-218088

Relief From Nature

Autor: David Leatherbarrow

Publikováno v: RA. Revista de Arquitectura, Vol 26 (2024)

Ground in this study is described as a basic premise for the emergence and retreat of images, in architecture, sculpture, painting, and landscape. Examples from different places and periods are examined, the latter ranging from the recent past, to th

Externí odkaz: https://doaj.org/article/026e9659f57a45d3ba81f1972bb34122

Real-World Data and Randomised Controlled Trials: The Salford Lung Study

Autor: Jørgen Vestbo, David Leather, Mike Thomas, Ashley Woodcock, Rupert Jones, Loretta Jacques

Publikováno v: Advances in Therapy

Traditional efficacy double-blind randomised controlled trials (DBRCTs) measure the benefit a treatment produces under near-ideal test conditions in highly selected patient populations; however, the behaviour of patients and investigators in such tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6436feeb722c85c69ca1cc44536c6946
https://doi.org/10.1007/s12325-019-01192-1

Chronic obstructive pulmonary disease exacerbation episodes derived from electronic health record data validated using clinical trial data

Autor: Kourtney J. Davis, Alexander Pate, David J. Webb, Jeanne M. Pimenta, Pinal Patel, Susan Collier, Matthew Sperrin, David Leather

Publikováno v: Sperrin, M, Patel, P, Davis, K J, Collier, S, Pate, A, Leather, D A & Pimenta, J M 2019, ' Chronic obstructive pulmonary disease exacerbation episodes derived from electronic health record data validated using clinical trial data ', Pharmacoepidemiology and Drug Safety . https://doi.org/10.1002/pds.4883
Pharmacoepidemiology and Drug Safety

PURPOSE: To validate an algorithm for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) episodes derived in an electronic health record (EHR) database, against AECOPD episodes collected in a randomized clinical trial using an elec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142371b9c0a4c1d7b061b900908a80e9
https://doi.org/10.1002/pds.4883

Follow-up interviews from The Salford Lung Study (COPD) and analyses per treatment and exacerbations

Autor: Diane Whalley, Nick Bosanquet, James Lay-Flurrie, David Leather, Rebecca Crawford, Lynda C. Doward, Henrik Svedsater

Publikováno v: npj Primary Care Respiratory Medicine, Vol 29, Iss 1, Pp 1-9 (2019)
NPJ Primary Care Respiratory Medicine

The Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) was a 12-month, Phase III, open-label, randomised study comparing the effectiveness and safety of initiating once-daily fluticasone furoate 100 µg/vilanterol 25 µg (FF/VI) w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4ce9856f61078be0f4ca66f5a24980
http://link.springer.com/article/10.1038/s41533-019-0123-0