Zobrazeno 1 - 10
of 37
pro vyhledávání: '"David Laurie"'
Autor:
David, Laurie1
Publikováno v:
Discover. May2008, Vol. 29 Issue 5, p26-28. 3p. 1 Color Photograph.
Autor:
Katja Matheis, Isabelle Clavier, David Laurie, Axel Kretschmer, Peter Thomann, Nadir Arber, Hannes Planatscher, Ina Schuppe-Koistinen, Thomas O. Joos, Christiane Andriamandroso, Hüseyin Firat, Steve Hall, Sarah Kraus, Teresa Padró, Lina Badimon, Béatrice Molac, Xavier Benain, Nicole Schneiderhan-Marra, Kaïdre Bendjama, Jens C. Goepfert, Annamaria Rossi, Jean-Marc Vidal, Michael Merz, P. Colman
Publikováno v:
Drug Discovery Today. 16:600-608
The importance of using translational safety biomarkers that can predict, detect and monitor drug-induced toxicity during human trials is becoming increasingly recognized. However, suitable processes to qualify biomarkers in clinical studies have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1318d01a4e915e96c303f4be02a199ec
https://doi.org/10.1016/j.drudis.2011.04.011
https://doi.org/10.1016/j.drudis.2011.04.011
Autor:
Ansar Jawaid, Timothy W. Robison, Sandra L Close, Ian Hunt, Sharada Louis Truter, Huixiao Hong, Catherine Cornu-Artis, Michael E. Burczynski, Laurent Essioux, Li Zhang, Peter Morrow, Weida Tong, Federico Goodsaid, Rosane Charlab, Issam Zineh, Shashi Amur, Lois Hinman, Lawrence J. Lesko, James T. Mayne, David Laurie, Kevin Carl, David Jacobson-Kram, Jacky Vonderscher, Jiri Aubrecht, Jennifer Catalano, Ina Schuppe-Koistinen, Marisa Papaluca-Amati, Leming Shi, Albert J. Fornace, Heng-Hong Li, Klaus Lindpaintner, Olivia Spleiss, Agnes Westelinck, John Roth
Publikováno v:
Nature Reviews Drug Discovery. 9:435-445
Heterogeneity in the underlying mechanisms of disease processes and inter-patient variability in drug responses are major challenges in drug development. To address these challenges, biomarker strategies based on a range of platforms, such as microar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2e34f16439e789f9572e1eb16801aa
https://doi.org/10.1038/nrd3116
https://doi.org/10.1038/nrd3116
Autor:
Laura Suter, Aliza Thompson, Ernie Harpur, Gerard Maurer, Bruno Flamion, Douglas C. Throckmorton, Phil Rossi, Jackie Akunda, Nancy Xu, Stefan Sultana, Federico Goodsaid, Jonathan A. Phillips, Sven A. Beushausen, Valérie G. Barlow, Denise Bounous, Jacky Vonderscher, David Gerhold, Sean P. Troth, Elizabeth Hausner, Karol L. Thompson, Matthew J. Schipper, Spiros Vamvakas, David Jacobson-Kram, William Taylor, Jean Marc Vidal, Beatriz Silva Lima, Albert F. Defelice, Supriya Jayadev, Magalie Guffroy, Yi Zhong Gu, James Eric McDuffie, Daniela Ennulat, Jeff Waring, Patricia Harlow, Leslie A. Obert, Sandra Snook, Frank D. Sistare, Eric A.G. Blomme, William B. Mattes, Craig P. Webb, Mark Pinches, David Honor, Romaldas Mačiulaitis, Myrtle Davis, Jinhe Lee, Frank Dieterle, Marisa Papaluca, Melanie Blank, Nathaniel Collins, William Baer, Peter L. Goering, Shen Xiao, Anthony J. Senagore, Krishna Prasad, Denise Robinson-Gravatt, Josef S Ozer, Eric Abadie, Graham Betton, Kevin Carl, Peter Kasper, David Laurie, Manisha Sonee, Dina Andrews-Cleavenger, Elizabeth G. Walker, Dan Holder, Markku Pasanen
Publikováno v:
Nature Biotechnology. 28:455-462
The first formal qualification of safety biomarkers for regulatory decision making marks a milestone in the application of biomarkers to drug development. Following submission of drug toxicity studies and analyses of biomarker performance to the Food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a6b13ac5e7fb2e36ce91685f63c53
https://doi.org/10.1038/nbt.1625
https://doi.org/10.1038/nbt.1625
Autor:
Stevenson, Bryan, Brown, Tina, Vanamee, Norman, Roth, Daryl, Porter, Dawn, David, Laurie, Elwes, Cary
Publikováno v:
Town & Country; Summer2020, Vol. 174 Issue 5465, p64-71, 8p, 7 Color Photographs
Autor:
David, Laurie (AUTHOR), Uhrenholdt, Kristin (AUTHOR)
Publikováno v:
Vegetarian Times. Sep2011, Issue 387, p62-69. 8p.
Publikováno v:
Heredity. 77:64-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df93c0dcf1962b62a6c32c9cf4fc8b9f
https://doi.org/10.1038/sj.hdy.6880340
https://doi.org/10.1038/sj.hdy.6880340
Autor:
Federico M, Goodsaid, Shashi, Amur, Jiri, Aubrecht, Michael E, Burczynski, Kevin, Carl, Jennifer, Catalano, Rosane, Charlab, Sandra, Close, Catherine, Cornu-Artis, Laurent, Essioux, Albert J, Fornace, Lois, Hinman, Huixiao, Hong, Ian, Hunt, David, Jacobson-Kram, Ansar, Jawaid, David, Laurie, Lawrence, Lesko, Heng-Hong, Li, Klaus, Lindpaintner, James, Mayne, Peter, Morrow, Marisa, Papaluca-Amati, Timothy W, Robison, John, Roth, Ina, Schuppe-Koistinen, Leming, Shi, Olivia, Spleiss, Weida, Tong, Sharada L, Truter, Jacky, Vonderscher, Agnes, Westelinck, Li, Zhang, Issam, Zineh
Publikováno v:
Nature reviews. Drug discovery. 9(6)
Heterogeneity in the underlying mechanisms of disease processes and inter-patient variability in drug responses are major challenges in drug development. To address these challenges, biomarker strategies based on a range of platforms, such as microar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1176c54f6d0619d7051797228170d3a7
https://pubmed.ncbi.nlm.nih.gov/20514070
https://pubmed.ncbi.nlm.nih.gov/20514070