Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David Lanar"'
Autor:
Carlota Dobaño, Itziar Ubillos, Chenjerai Jairoce, Ben Gyan, Marta Vidal, Alfons Jiménez, Rebeca Santano, David Dosoo, Augusto J. Nhabomba, Aintzane Ayestaran, Ruth Aguilar, Nana Aba Williams, Núria Díez-Padrisa, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Deepak Gaur, Evelina Angov, Kwaku Poku Asante, Seth Owusu-Agyei, Clarissa Valim, Benoit Gamain, Ross L. Coppel, David Cavanagh, James G. Beeson, Joseph J. Campo, Gemma Moncunill
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Vaccination and naturally acquired immunity against microbial pathogens may have complex interactions that influence disease outcomes. To date, only vaccine-specific immune responses have routinely been investigated in malaria vac
Externí odkaz:
https://doaj.org/article/b537671e318343a6a6e9016896cf4fdc
Autor:
Itziar Ubillos, Alfons Jiménez, Marta Vidal, Paul W. Bowyer, Deepak Gaur, Sheetij Dutta, Benoit Gamain, Ross Coppel, Virander Chauhan, David Lanar, Chetan Chitnis, Evelina Angov, James Beeson, David Cavanagh, Joseph J. Campo, Ruth Aguilar, Carlota Dobaño
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background The quantitative suspension array technology (qSAT) is a useful platform for malaria immune marker discovery. However, a major challenge for large sero-epidemiological and malaria vaccine studies is the comparability across labora
Externí odkaz:
https://doaj.org/article/5ba8377aef2545d38add042e560f8738
Autor:
Grace E. Weber, Michael T. White, Anna Babakhanyan, Peter Odada Sumba, John Vulule, Dylan Ely, Chandy John, Evelina Angov, David Lanar, Sheetij Dutta, David L. Narum, Toshihiro Horii, Alan Cowman, James Beeson, Joseph Smith, James W. Kazura, Arlene E. Dent
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract We sought to identify a subset of Plasmodium falciparum antibody targets that would inform monitoring efforts needed to eliminate malaria in high transmission settings. IgG antibodies to 28 recombinant Pf antigens were measured in residents
Externí odkaz:
https://doaj.org/article/b4b23d2c9c8c47a69405060fca7a2b2d
Autor:
Carlota Dobaño, Rebeca Santano, Marta Vidal, Alfons Jiménez, Chenjerai Jairoce, Itziar Ubillos, David Dosoo, Ruth Aguilar, Nana Aba Williams, Núria Díez-Padrisa, Aintzane Ayestaran, Clarissa Valim, Kwaku Poku Asante, Seth Owusu-Agyei, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Evelina Angov, Benoit Gamain, Ross L. Coppel, James G. Beeson, Linda Reiling, Deepak Gaur, David Cavanagh, Ben Gyan, Augusto J. Nhabomba, Joseph J. Campo, Gemma Moncunill
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Naturally acquired immunity (NAI) to Plasmodium falciparum malaria is mainly mediated by IgG antibodies but the subclasses, epitope targets and effector functions have not been unequivocally defined. Dissecting the type and specificity of antibody re
Externí odkaz:
https://doaj.org/article/32aa5029682c4bfd9b0f38f363686bb5
Autor:
Ae Kim, Isamu Hartman, David Lanar, Tatiana Boronina, Robert Cole, Scheherazade Sadegh-Nasseri
Publikováno v:
The Journal of Immunology. 194:183.14-183.14
A cell-free antigen processing system for MHC class II was recently reported that has proved to be effective in identifying physiologically relevant CD4+ T cell epitopes from proteins (Hartman/Kim, et al. Nat Med. 16, pp1333-40 (2010)). This system h
Autor:
Thomas Powell, Jie Tang, Andrea Jacobs, Mary DeRome, Naveen Palath, Edwin Cardenas, James Boyd, Elizabeth Nardin, Stephen Kaba, David Lanar
Publikováno v:
The Journal of Immunology. 192:141.21-141.21
We have previously shown that synthetic LbL-MP vaccines containing the conserved T1B repeat and T* epitopes from the P. falciparum circumsporozoite (PfCS) protein elicit a protective antibody response in mice. Immunogenicity and efficacy of these LbL
Autor:
Ae Kim, Isamu Hartman, Bradley Poore, Tatiana Boronina, David Lanar, Urszula Krzych, Robert Cole, Scheherazade Sadegh-Nasseri
Publikováno v:
The Journal of Immunology. 190:41.5-41.5
We developed a minimalist cell-free antigen-processing system for MHC class II that can identify physiologically selected T cell epitopes from antigens. The system utilizes purified proteins: HLA-DR1, cathepsin B, H, S, and HLA-DM. It was designed to
Autor:
Ae Kim, Isamu Hartman, David Lanar, Tatiana Boronina, Robert Cole, Scheherazade Sadegh-Nasseri
Publikováno v:
The Journal of Immunology. 186:100.21-100.21
Immunodominance is defined as restricted responsiveness of T cells to a few selected epitopes from complex antigens. We have established a reductionist cell-free antigen-processing system for MHC class II that constitutes five purified components: HL