Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David L. Thomasson"'
Publikováno v:
Cellular Immunology. 38:214-218
A monovalent subunit of concanavalin A (Con A) was tested for mitogenic effects on murine splenic lymphocytes in vitro . In contrast to the effects of intact Con A, the monovalent derivative was not mitogenic at any concentration tested. Furthermore,
Publikováno v:
Kidney International. 33:71-76
Cortical interstitial cell interactions induce sensitivity of hydronephrotic kidney to bradykinin. The mechanism of the increased prostaglandin production and induction of sensitivity to bradykinin by the cortex of the hydronephrotic rabbit kidney wa
Publikováno v:
Carbohydrate Research. 46:111-118
Metal-free concanavalin A is readily and irreversibly inactivated by temperatures above 60°. Manganese ion completely prevents the thermal aggregation of the protein at 60 and 70°, and partially protects at 80°, but shows no protective properties
Publikováno v:
Kidney International. (3):458-464
Renal disease profoundly alters cortical interstitial cell function. Interstitial cells were cultured from explants of the unilaterally hydronephrotic, contralateral, and normal kidneys. Two types of cells were identified in culture, macrophages, and
Publikováno v:
Cellular immunology. 68(2)
A hybridoma, F133, that produces macrophage activation factor (MAF) after mitogen stimulation was developed by fusing the AKR-derived BW5147 thymoma with alloantigen-stimulated C3H/HeJ splenocytes. F133 supernatants were shown to contain MAF, migrati
Publikováno v:
FEBS letters. 52(2)
The lectin, concanavalin A (con A), is known to have at least four distinct binding sites. On site binds a transition metal, which, when occupied, activates a calcium binding site [ 11. When both metal binding sites are filed, a saccharide binding si
Publikováno v:
Carcinogenesis. 9(7)
Prostaglandins play a potential key role in the pathogenesis of urinary bladder cancer. Bradykinin and TPA increases in prostaglandin (PG)E2 levels were compared in primary cultures of human urothelial cells. Increased PGE2 levels were dependent upon
Publikováno v:
Journal of cellular physiology. 110(1)
The activation of pure populations of cloned peritoneal macrophages for tumor cell cytotoxicity by Con A was demonstrated using a recently developed tumor cell clonogenic assay. Cloned macrophages were rendered cytotoxic by Con A at concentrations ab
Publikováno v:
Biochemical pharmacology. 34(9)
Isolated rabbit renal papillary collecting tubule cells were used examine the effects of phospahodiesterase inhibitors on intracellular cyclic AMP and prostaglandin synthesis. Experiments performed on confluent primary tissue culutures demonstrated t
Publikováno v:
The Journal of Parasitology. 59:738