Zobrazeno 1 - 10
of 22
pro vyhledávání: '"David L. Story"'
Autor:
David L. Story, Charles Tong, Alice S. Tu, Charles A. Tyson, Gary M. Williams, Harry A. Milman, Edward S. Riccio, A Sivak
Publikováno v:
Annals of the New York Academy of Sciences. 534:521-530
Nine chlorinated aliphatics (CAs) were examined in a rat liver foci assay for tumor initiating and promoting activities. In this model, young adult male Osborne Mendel rats were first subjected to a partial hepatectomy, the test chemical was then adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840c29f6c651060e34f3d29d08a25039
https://doi.org/10.1111/j.1749-6632.1988.tb30143.x
https://doi.org/10.1111/j.1749-6632.1988.tb30143.x
Autor:
David L. Story, Richard A. Freedland
Publikováno v:
Toxicology and Applied Pharmacology. 43:547-557
The effects of feeding DDT on liver gluconeogenesis were studied in isolated hepatocytes. Rats were fed 1000 ppm o,p′ -DDT for 2 weeks and starved for 48 hr. Food intake and weight gain were not affected by DDT feeding. Gluconeogenic rates were sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50164a9fe3262e371aa63acf67086089
https://doi.org/10.1016/s0041-008x(78)80014-3
https://doi.org/10.1016/s0041-008x(78)80014-3
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 6, Pp 916-920 (1981)
The urinary excretion and the incorporation into lipids of R[3-14C]mevalonate was investigated in isolated rat kidneys perfused with physiological concentration sof the substrate (80-500 pmol/ml). The clearance of R[3-14C]mevalonate and of the unnatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc617f35034d953ff65654c5c06ad3f3
http://www.sciencedirect.com/science/article/pii/S0022227520373296
http://www.sciencedirect.com/science/article/pii/S0022227520373296
Autor:
Andrew J. Clifford, David L. Story
Publikováno v:
The Journal of Nutrition. 106:435-442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4e2b383e7bc1527d04721f80ed1026
https://doi.org/10.1093/jn/106.3.435
https://doi.org/10.1093/jn/106.3.435
Publikováno v:
Toxicology and Applied Pharmacology. 63:275-280
Urea synthesis from 5 mm NH4Cl plus 10 mm ornithine was decreased in isolated hepatocytes from rats fed 1000 ppm o,p′-DDT for 2 weeks and starved for 48 hr. DDT feeding had no effect on urea synthesis from 10 mm alanine, serine, or threonine in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056a9e15d28e4f221268a8612d64cf1a
https://doi.org/10.1016/0041-008x(82)90050-3
https://doi.org/10.1016/0041-008x(82)90050-3
Publikováno v:
Journal of Biological Chemistry. 259:372-377
The shunt pathway of mevalonate metabolism (Edmond, J., and Popjak, G. (1974) J. Biol. Chem. 249, 66-71) has been studied in isolated kidneys from rats perfused with physiological concentrations of variously labeled [14C]- and [3H]mevalonates. The ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ee0f5c14e59c7433ecf06ca2263f7b
https://doi.org/10.1016/s0021-9258(17)43669-6
https://doi.org/10.1016/s0021-9258(17)43669-6
Publikováno v:
Proceedings of the National Academy of Sciences. 77:4417-4419
The uptake of free choline by isolated perfused rat liver was characterized. A saturable uptake mechanism [Ka = 0.17 +/- 0.07 mM (SD); Vmax = 0.84 +/- 0.16 mumol/min X g dry weight] and a nonsaturable mechanism (through which uptake is proportional t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3cb958bd7ac9b81e068e905e78cec1
https://doi.org/10.1073/pnas.77.8.4417
https://doi.org/10.1073/pnas.77.8.4417
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 3(2)
The release of lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) from rat and mouse hepatocytes was used to rank the in vitro cytotoxic potential of eight chlorinated aliphatic compounds. The rankings were compared with toxicity rankin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d64aa3ba15efde9fbab11d6f4f9cbe2
https://pubmed.ncbi.nlm.nih.gov/20702312
https://pubmed.ncbi.nlm.nih.gov/20702312
Autor:
Richard A. Freedland, David L. Story
Publikováno v:
Toxicology and applied pharmacology. 50(2)
The effect of DDT feeding and food deprivation on liver and plasma amino acid concentrations was studied. DDT feeding had no effect on plasma amino acids but resulted in an increase in the concentration of liver isoleucine, ornithine, phenylalanine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37a03679efc428429865bcf27692ed2
https://pubmed.ncbi.nlm.nih.gov/505461
https://pubmed.ncbi.nlm.nih.gov/505461
Publikováno v:
Toxicology and industrial health. 2(4)
Nine chlorinated aliphatics (CAs)—1,1-dichloroethane, 1,2-dichloro ethane, 1,1,1-trichloroethane, 1,1,2-trichloroethane, trichloro ethylene, tetrachloroethylene, 1,1,1,2-tetrachloroethane, 1,1,2,2- tetrachloroethane, and hexachloroethane—were exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a80565edb2283757aa212c09ba459b0
https://pubmed.ncbi.nlm.nih.gov/3296316
https://pubmed.ncbi.nlm.nih.gov/3296316