Zobrazeno 1 - 10
of 40
pro vyhledávání: '"David L. Simpson"'
Autor:
Natalia Vapniarsky, David L. Simpson, Boaz Arzi, Nopmanee Taechangam, Naomi J. Walker, Carissa Garrity, Evelyn Bulkeley, Dori L. Borjesson
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Feline chronic gingivostomatitis (FCGS) is an immune-mediated inflammatory condition affecting the oral mucosa that results in substantial pain and suffering. The goal of this study was to complete an in-depth immunohistochemistry analysis of affecte
Externí odkaz:
https://doaj.org/article/a998f3269bcf48aab7de69b3b0633475
Autor:
Sudhish Sharma, Ling Chen, Shalesh Kaushal, Yin Guo, Savitha Deshmukh, Keerti Balachandran, Brody Wehman, Osama T. Siddiqui, Evan Colletti, Rachana Mishra, Sunjay Kaushal, David L. Simpson, Srinivasa Raju Datla
Publikováno v:
Stem Cells. 33:1213-1229
We have demonstrated that human neonatal cardiosphere-derived cells (CDCs) derived from the young are more regenerative due to their robust secretome. However, it is unclear how the decompensated pediatric heart impacts the functional activity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932471943f8a164234b268581a5a3b5c
https://doi.org/10.1002/stem.1937
https://doi.org/10.1002/stem.1937
Publikováno v:
Seismological Research Letters. 83:281-286
Online material: Sample SeisSound video products; MATLAB computer codes; sample data set. The increased popularity of YouTube videos has changed the format of how information is distributed and assimilated, highlighting the importance of including au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7061a9472c7adb9a283d865c7c83598a
https://doi.org/10.1785/gssrl.83.2.281
https://doi.org/10.1785/gssrl.83.2.281
Autor:
Deli Wang, Kalpana Vijayan, Evan Colletti, Samuel C. Dudley, Brandon L. Walker, Graça Almeida-Porada, Rachana Mishra, Thomas S Matthiesen, Loren E. Wold, David L. Simpson, Saik Kia Goh, Carl L. Backer, Sunjay Kaushal, Daniel A. Harrington
Publikováno v:
Circulation. 123:364-373
Background— Human cardiac progenitor cells (hCPCs) may promote myocardial regeneration in adult ischemic myocardium. The regenerative capacity of hCPCs in young patients with nonischemic congenital heart defects for potential use in congenital hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98ac6961f2c26f0d18bf32e817a7b02
https://doi.org/10.1161/circulationaha.110.971622
https://doi.org/10.1161/circulationaha.110.971622
Autor:
Samuel C. Dudley, David L. Simpson
Publikováno v:
Current Stem Cell Research & Therapy. 4:210-223
Heart failure accounts for more deaths in the United States than any other detrimental human pathology. Recently, repairing the heart after seemingly irreversible injury leading to heart failure appears to have come within reach. Cellular cardiomyopl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914260f97e64b3e93453b0fd2fbb8aee
https://doi.org/10.2174/157488809789057437
https://doi.org/10.2174/157488809789057437
Autor:
Andrea Califano, Barry Honig, David L. Simpson, Alexander Lachmann, Joshua Broyde, Alejandro Sweet-Cordero, Federico M. Giorgi, Diana Murray
Publikováno v:
Cancer Research. 77:LB-289
Elucidation of the full complement of members of oncogenic signaling pathways is critical for understanding dysregulated function in cancers. Our knowledge of experimentally verified human gene-regulatory networks and protein-protein interactions rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f8c6f7f0eee96d128b69d56313ba4b2
https://doi.org/10.1158/1538-7445.am2017-lb-289
https://doi.org/10.1158/1538-7445.am2017-lb-289
Autor:
Ling Chen, Sunjay Kaushal, David L. Simpson, Sudhish Sharma, Evan Colletti, Savitha Deshmukh, Rachana Mishra
Publikováno v:
Circulation Research. 115
Background: The potential of novel cell based therapies using cardiosphere derived cells (CDCs) to replace or repair damaged cardiac tissue is an attractive therapy and Phase I clinical trials in adults report encouraging results. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99280545a2c388ecab7db376d7981bc
https://doi.org/10.1161/res.115.suppl_1.16
https://doi.org/10.1161/res.115.suppl_1.16
Autor:
Mani Anamalai, Sudhish Sharma, Brandon L. Walker, Rachana Mishra, Ishwar S. Singh, Manuela Zampino, David L. Simpson, Savitha Deshmukh, Jay Patel, Shalesh Kaushal, Sunjay Kaushal
Publikováno v:
Cell stresschaperones. 20(1)
Protein homeostatic regulators have been shown to ameliorate single, loss-of-function protein diseases but not to treat broader animal disease models that may involve cell death. Diseases often trigger protein homeostatic instability that disrupts th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e31cce994215f97c66f3b6b2ae0d52
https://pubmed.ncbi.nlm.nih.gov/25300203
https://pubmed.ncbi.nlm.nih.gov/25300203
Autor:
Vasiliy Galat, Yekaterina Galat, David L. Simpson, Brody Wehman, Sunjay Kaushal, Rachana Mishra, Sudhish Sharma
Publikováno v:
The Annals of thoracic surgery. 98(3)
Background Pediatric patients requiring valve replacement will likely require reoperations due to a progressive deterioration of valve durability and limited repair and growth potential. To address these concerns, we sought to generate a biologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c8e02fde3bc43f7acdbe43ea89ccf0
https://pubmed.ncbi.nlm.nih.gov/25038011
https://pubmed.ncbi.nlm.nih.gov/25038011
Autor:
David L Simpson, Agnieszka Blusztajn, Ileana Valle, Michelle Kreke, Linda Marban, Rachel R Smith
Publikováno v:
Circulation Research. 113
Currently, allogeneic cardiosphere-derived cells (CDCs) are being tested in a phase I/II clinical trial. Our manufacturing process utilizes the atria and other regions of the heart to build a master cell bank, but leaves the left ventricle (LV) intac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bac097d24aff122fc2091169c10912c
https://doi.org/10.1161/res.113.suppl_1.a260
https://doi.org/10.1161/res.113.suppl_1.a260