Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David L. Schonberg"'
Autor:
Ann Mari Rosager, Mia D Sørensen, Rikke H Dahlrot, Steinbjørn Hansen, David L Schonberg, Jeremy N Rich, Justin D Lathia, Bjarne W Kristensen
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182954 (2017)
Astrocytic brain tumors are the most frequent primary brain tumors. Treatment with radio- and chemotherapy has increased survival making prognostic biomarkers increasingly important. The aim of the present study was to investigate the expression and
Externí odkaz:
https://doaj.org/article/c341d9379b374fc09fe174666de7839f
Autor:
Mia D. Sørensen, Bjarne Winther Kristensen, Ann Mari Rosager, Jeremy N. Rich, David L. Schonberg, Steinbjørn Hansen, Justin D. Lathia, Rikke Hedegaard Dahlrot
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182954 (2017)
Rosager, A M, Sørensen, M D, Dahlrot, R H, Hansen, S, Schonberg, D L, Rich, J N, Lathia, J D & Kristensen, B W 2017, ' Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors : Expression and prognostic value ', PLOS ONE, vol. 12, no. 8, e0182954 . https://doi.org/10.1371/journal.pone.0182954
PLoS ONE
Rosager, A M, Sørensen, M D, Dahlrot, R H, Hansen, S, Schonberg, D L, Rich, J N, Lathia, J D & Kristensen, B W 2017, ' Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors : Expression and prognostic value ', PLOS ONE, vol. 12, no. 8, e0182954 . https://doi.org/10.1371/journal.pone.0182954
PLoS ONE
Astrocytic brain tumors are the most frequent primary brain tumors. Treatment with radio- and chemotherapy has increased survival making prognostic biomarkers increasingly important. The aim of the present study was to investigate the expression and
Publikováno v:
Experimental Neurology. 248:53-61
Excess iron accumulation within the spinal cord is thought to exacerbate tissue damage and limit functional recovery after traumatic spinal cord injury (SCI). An optimal treatment to reverse or prevent damage would be to deliver an iron chelator syst
Autor:
Ping Wei, Fatma Rezan Sahinkaya, Dana M. McTigue, Evan Z. Goldstein, Phillip G. Popovich, David L. Schonberg
Publikováno v:
The Journal of Neuroscience. 32:5374-5384
Injured CNS tissue often contains elevated iron and its storage protein ferritin, which may exacerbate tissue damage through pro-oxidative mechanisms. Therefore, therapeutic studies often target iron reduction as a neuroprotective strategy. However,
Publikováno v:
Nature Genetics. 45:1105-1107
Identifying genomic alterations in cancer does not guarantee therapeutic benefit. A new study combining DNA and RNA sequencing with functional validation uncovers new genetic driver alterations in glioblastoma with potential for clinical translation.
Autor:
Howard Y. Chang, Evan Noch, Markus J. Bookland, Kathrin Geiger, Joanna J. Phillips, Janine M. Lupo, Kamel Khalili, Simone P. Niclou, Anita B. Hjelmeland, L. Karl Olson, Ping Huang, Kenneth Schwartz, Kah Suan Lim, Antoinette Price, Georgina Perez-Liz, Sarah M. Woods, John C. Kappes, Charles G. Eberhart, Morgane Sanzey, Dana A M Mustafa, Gelareh Zadeh, Aaron E. Robinson, Alessia Lodi, Dietmer Krex, Jeremy N. Rich, Sigrid M. A. Swagemakers, Justin D. Lathia, Candece L. Gladson, Graeme Eisenhofer, Brent A. Orr, Siti Aminah Abdul Rahim, Johan M. Kros, Sergio Pina-Oviedo, Kah Jing Lim, Alenoush Vartanian, Jennifer Gordon, Russel O. Pieper, Eli E. Bar, Robert M. Danforth, Wei M. Liu, John M. Heddleston, Rolf Bjerkvig, Sabrina M. Ronen, Myriam M. Chaumeil, Amy S. Nowacki, Mirko Peitzsch, David L. Schonberg, Hikari A. I. Yoshihara, Luis Del Valle, Clark W. Distelhorst, Tareq A. Juratli, Sanjay K. Singh, Peter J. van der Spek, Gabriele Schackert
Publikováno v:
Neuro-Oncology. 14:vi53-vi55
Autor:
James K. Liu, David L. Schonberg, Jeremy N. Rich, Justin D. Lathia, Jennifer S. Yu, William A. Flavahan, Anita B. Hjelmeland, Jianghong Man, James S. Hale, Daniel Lubelski, Erin E. Mulkearns-Hubert, Qiulian Wu
Publikováno v:
Cell death and differentiation. 21(8)
Glioblastoma is the most common primary intrinsic brain tumor and remains incurable despite maximal therapy. Glioblastomas display cellular hierarchies with self-renewing glioma-initiating cells (GICs) at the apex. To discover new GIC targets, we use
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(36)
Cells proliferate or differentiate. Conventional wisdom holds that these two dominant forces regulating cell state display a yin-yang relationship, but like all reductionist conclusions, the absolute dichotomization of cell behaviors must be consider
Publikováno v:
Molecular aspects of medicine. 39
Glioblastoma (GBM) is the most prevalent primary brain tumor and ranks among the most lethal of human cancers with conventional therapy offering only palliation. Great strides have been made in understanding brain cancer genetics and modeling these t
Autor:
Jessica K. Alexander, David L. Schonberg, John C. Gensel, Dana M. McTigue, Phillip G. Popovich
There is a need to develop therapies that promote growth or remyelination of mammalian CNS axons. Although the feasibility of pre-clinical treatment strategies should be tested in animal models, in vitro assays are usually faster and less expensive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a7be4475cfa4c39f69516744246c39
https://europepmc.org/articles/PMC2911480/
https://europepmc.org/articles/PMC2911480/