Zobrazeno 1 - 10
of 108
pro vyhledávání: '"David L. Moyes"'
Autor:
Blair Merrick, Chrysi Sergaki, Lindsey Edwards, David L. Moyes, Michael Kertanegara, Désirée Prossomariti, Debbie L. Shawcross, Simon D. Goldenberg
Publikováno v:
Infectious Disease Reports, Vol 15, Iss 3, Pp 238-254 (2023)
Antimicrobial resistance (AMR) is one of the greatest challenges facing humanity, causing a substantial burden to the global healthcare system. AMR in Gram-negative organisms is particularly concerning due to a dramatic rise in infections caused by e
Externí odkaz:
https://doaj.org/article/7c363740330745b9ba29381242a21aa4
Autor:
Neelu Begum, Sunjae Lee, Theo John Portlock, Aize Pellon, Shervin Dokht Sadeghi Nasab, Jens Nielsen, Mathias Uhlen, David L. Moyes, Saeed Shoaie
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Metabolic differences between Candida species are uncovered using the BioFung database alongside genomic and metabolic analysis.
Externí odkaz:
https://doaj.org/article/ed773267446344fa9204e94dfdd48fed
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Fungal communities (mycobiome) have an important role in sustaining the resilience of complex microbial communities and maintenance of homeostasis. The mycobiome remains relatively unexplored compared to the bacteriome despite increasing evidence hig
Externí odkaz:
https://doaj.org/article/bb285fef3efa469dbc6ffcb6d20e50a2
Autor:
Ceri Proffitt, Gholamreza Bidkhori, Sunjae Lee, Abdellah Tebani, Adil Mardinoglu, Mathias Uhlen, David L. Moyes, Saeed Shoaie
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104513- (2022)
Summary: The human gut microbiome has been associated with metabolic disorders including obesity, type 2 diabetes, and atherosclerosis. Understanding the contribution of microbiome metabolic changes is important for elucidating the role of gut bacter
Externí odkaz:
https://doaj.org/article/1218c72e51e849f2b695c26beafefd83
Autor:
Jonathan P. Richardson, Rhys Brown, Nessim Kichik, Sejeong Lee, Emily Priest, Selene Mogavero, Corinne Maufrais, Don N. Wickramasinghe, Antzela Tsavou, Natalia K. Kotowicz, Olivia W. Hepworth, Ana Gallego-Cortés, Nicole O. Ponde, Jemima Ho, David L. Moyes, Duncan Wilson, Christophe D’Enfert, Bernhard Hube, Julian R. Naglik
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Candidalysin is the first cytolytic peptide toxin identified in any human fungal pathogen. Candidalysin is secreted by Candida albicans and is critical for driving infection and host immune responses in several model systems. However, Candid
Externí odkaz:
https://doaj.org/article/7a4e9cd34a2f4184b02a7bf66ce31248
Autor:
Máté Vadovics, Jemima Ho, Nóra Igaz, Róbert Alföldi, Dávid Rakk, Éva Veres, Balázs Szücs, Márton Horváth, Renáta Tóth, Attila Szücs, Andrea Csibi, Péter Horváth, László Tiszlavicz, Csaba Vágvölgyi, Joshua D. Nosanchuk, András Szekeres, Mónika Kiricsi, Rhonda Henley-Smith, David L. Moyes, Selvam Thavaraj, Rhys Brown, László G. Puskás, Julian R. Naglik, Attila Gácser
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Oral squamous cell carcinoma (OSCC) is associated with oral Candida albicans infection, although it is unclear whether the fungus promotes the genesis and progression of OSCC or whether cancer facilitates fungal growth. In this study, we inv
Externí odkaz:
https://doaj.org/article/93f44f6d7ed54b7a813a14b3df629848
Autor:
Victoria R. Carr, Elizabeth A. Witherden, Sunjae Lee, Saeed Shoaie, Peter Mullany, Gordon B. Proctor, David Gomez-Cabrero, David L. Moyes
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Antimicrobial resistance (AMR) represents a global health threat. Here, the authors analyse the oral and gut resistomes from metagenomes of diverse populations and find that the oral resistome harbours higher abundance but lower diversity of antimicr
Externí odkaz:
https://doaj.org/article/735991a569e94940aaa4225c473a42a0
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/c95ac1bd89df4dd4a45578c3a679db93
Autor:
Sophie Austermeier, Marina Pekmezović, Pauline Porschitz, Sejeong Lee, Nessim Kichik, David L. Moyes, Jemima Ho, Natalia K. Kotowicz, Julian R. Naglik, Bernhard Hube, Mark S. Gresnigt
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Albumin is the most abundant serum protein in humans. During inflammation, serum albumin levels decrease drastically, and low albumin levels are associated with poor patient outcome.
Externí odkaz:
https://doaj.org/article/4e001832d9a6497d9014969857ceb712
Autor:
Jemima Ho, Xuexin Yang, Spyridoula-Angeliki Nikou, Nessim Kichik, Andrew Donkin, Nicole O. Ponde, Jonathan P. Richardson, Remi L. Gratacap, Linda S. Archambault, Christian P. Zwirner, Celia Murciano, Rhonda Henley-Smith, Selvam Thavaraj, Christopher J. Tynan, Sarah L. Gaffen, Bernhard Hube, Robert T. Wheeler, David L. Moyes, Julian R. Naglik
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Candida albicans is an opportunistic fungus primarily affecting immunocompromised patients. Here, the authors identify a novel mechanism of host immune stimulation and highlight candidalysin and EGFR signalling components as potential targets for pro
Externí odkaz:
https://doaj.org/article/5a35ef4f63da4f5da3fd3d4b2fc4fa96