Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David L. Liu"'
Autor:
Richard P. Junghans, Rosa M. Gonzalo-Daganzo, David L. Liu, Erica M. Gomes, Agnes S.Y. Lo, Peter C.R. Emtage
Purpose: This report describes the development and preclinical qualification tests of second-generation anti-carcinoembryonic (CEA) designer T cells for use in human trials.Experimental Design: The progenitor first-generation immunoglobulin-T-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609f06263a3fd6e3e52001c2a003e799
https://doi.org/10.1158/1078-0432.c.6517050
https://doi.org/10.1158/1078-0432.c.6517050
Autor:
Richard P. Junghans, Rosa M. Gonzalo-Daganzo, David L. Liu, Erica M. Gomes, Agnes S.Y. Lo, Peter C.R. Emtage
Supplementary Data from Second-Generation Anti–Carcinoembryonic Antigen Designer T Cells Resist Activation-Induced Cell Death, Proliferate on Tumor Contact, Secrete Cytokines, and Exhibit Superior Antitumor Activity In vivo: A Preclinical Evaluatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630a40d59c3a5498dfe3137da91c74a5
https://doi.org/10.1158/1078-0432.22439610.v1
https://doi.org/10.1158/1078-0432.22439610.v1
Supplementary Data from Anti-GD3 Chimeric sFv-CD28/T-Cell Receptor ζ Designer T Cells for Treatment of Metastatic Melanoma and Other Neuroectodermal Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7035b5e5c34a4b7b93b5a006fb11beac
https://doi.org/10.1158/1078-0432.22442975.v1
https://doi.org/10.1158/1078-0432.22442975.v1
Purpose: The aims of this study are to compare antitumor activities of two generations of GD3-specific chimeric antigen receptors (CAR) in human primary T lymphocytes in vitro and to evaluate the antitumor efficacy of using a combination of systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6dfdcf916abe12b50a3ab2ac27156f
https://doi.org/10.1158/1078-0432.c.6519593.v1
https://doi.org/10.1158/1078-0432.c.6519593.v1
Autor:
Clement Ma, Francisca Vazquez, Eliezer M. Van Allen, Meng Xiao He, Katherine A. Janeway, Michael C. Bassik, James M. McFarland, Jesse S. Boehm, Jett Crowdis, Alma Imamovic, Alexander Gusev, Kimberly Stegmaier, Kyuho Han, Felix Dietlein, David L. Liu, Neekesh V. Dharia, Jake Conway, Jihye Park, Brian J. Haas, Riaz Gillani, Bo Kyung A. Seong, Saif Alimohamed
Publikováno v:
Cancer Research. 81:96-96
Gene fusions frequently result from rearrangements in cancer genomes. In many instances, they play an important role in oncogenesis; in other instances, they are thought to be passenger events. Regulatory element rearrangements and copy number altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3454d763563337634d767d62ac616984
https://doi.org/10.1158/1538-7445.am2021-96
https://doi.org/10.1158/1538-7445.am2021-96
Autor:
Scott C. Carter, David L. Liu, Megha Shettigar, Scott J. Rodig, Ana Lako, Priya Pancholi, Diana Miao, Bart Lutterbach, Michael Manos, Cécile Gstalder, Rizwan Haq, Elizabeth L. Buchbinder, Ryan C. Brennick, F. Stephen Hodi, Alex Devine, Evisa Gjini, Eliezer M. Van Allen, Charles Yoon, Gordon J. Freeman, Vanesa Rojas-Rudilla
Publikováno v:
Cancer Immunology Research. 8:A48-A48
Immunotherapies such as anti-PD-1 antibodies can induce durable responses in a subset of cancer patients, but intrinsic or acquired resistance occurs in most cases. Understanding the molecular mechanisms that drive resistance and response to immunoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4cfa30583822f6b43dde2004125d87
https://doi.org/10.1158/2326-6074.tumimm19-a48
https://doi.org/10.1158/2326-6074.tumimm19-a48
Autor:
Francisco Sanchez-Vega, Marco Mina, Joshua Armenia, Walid K. Chatila, Augustin Luna, Konnor La, Sofia Dimitriadoy, David L. Liu, Havish S. Kantheti, Zachary Heins, Angelica Ochoa, Benjamin Gross, Jianjiong Gao, Hongxin Zhang, Ritika Kundra, Cyriac Kandoth, Istemi Bahceci, Leonard Dervishi, Ugur Dogrusoz, Wanding Zhou, Hui Shen, Peter W. Laird, Alice H. Berger, Trever G. Bivona, Alexander J. Lazar, Gary Hammer, Thomas Giordano, Lawrence Kwong, Grant McArthur, Chenfei Huang, Mitchell J. Frederick, Frank McCormick, Matthew Meyerson, The Cancer Genome Atlas Research Network, Eliezer Van Allen, Andrew D. Cherniack, Giovanni Ciriello, Chris Sander, Nikolaus Schultz
Publikováno v:
Cancer Research. 78:3302-3302
Over the past decade, The Cancer Genome Atlas (TCGA) has profiled more than 11,000 tumors spanning 33 distinct cancer types. The TCGA PanCanAtlas is a collaborative project by the TCGA Research Network that aims to address relevant overarching questi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2fa17eedb1924b23f1c897397321cf4
https://doi.org/10.1158/1538-7445.am2018-3302
https://doi.org/10.1158/1538-7445.am2018-3302
Publikováno v:
Clinical Cancer Research. 16:2769-2780
Purpose: The aims of this study are to compare antitumor activities of two generations of GD3-specific chimeric antigen receptors (CAR) in human primary T lymphocytes in vitro and to evaluate the antitumor efficacy of using a combination of systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c46e373a56dd57f3d1e3d2857a020c
https://doi.org/10.1158/1078-0432.ccr-10-0043
https://doi.org/10.1158/1078-0432.ccr-10-0043
Autor:
David L. Liu, Richard P. Junghans, Agnes Lo, Rosa M Gonzalo-Daganzo, Peter C. R. Emtage, Erica M. Gomes
Publikováno v:
Clinical Cancer Research. 14:8112-8122
Purpose: This report describes the development and preclinical qualification tests of second-generation anti-carcinoembryonic (CEA) designer T cells for use in human trials.Experimental Design: The progenitor first-generation immunoglobulin-T-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe89bbf4326fe123f42ab2541f812c86
https://doi.org/10.1158/1078-0432.ccr-07-4910
https://doi.org/10.1158/1078-0432.ccr-07-4910
Publikováno v:
Journal of Surgical Research. 71:67-72
Interstitial laser-induced thermotherapy (ILT) destroys tumors thermally, ILT was performed for treatment of liver tumors in rats to investigate the effect of hepatic inflow occlusion on temperature distribution and lesion size. Tumors were irradiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6478fc063a35e1c69d8ed60ba95efaf4
https://doi.org/10.1006/jsre.1997.5121
https://doi.org/10.1006/jsre.1997.5121