Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David L. Ladd"'
Publikováno v:
Journal of Magnetic Resonance Imaging. 13:615-618
A preparation of ultra-small superparamagnetic iron oxide (USPIO) particles coupled to an RGD peptide (RGD-USPIO) was investigated as an MR contrast agent, targeted to activated platelets, in both ex vivo and in vivo thrombus models. Thrombus visuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::831c5d5a0448318eb5e0eb61287ed590
https://doi.org/10.1002/jmri.1086
https://doi.org/10.1002/jmri.1086
Autor:
Terry S. Desser, Donna Wei, John L. Toner, Robert A. Snow, Gang Wu, Jennifer Eck, Robert Hollister, Daniel Joseph Delecki, Xin Peng, Vinay Chandrakant Desai, Kenneth E. Kellar, David L. Ladd, Gemma Raymond, Lewis B. Kinter, Daniel L. Rubin
Publikováno v:
Bioconjugate Chemistry. 10:361-370
We have synthesized and evaluated five series of polymeric gadolinium chelates which are of interest as potential MRI blood pool contrast agents. The polymers were designed so that important physical properties including molecular weight, relaxivity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c93febae98715b019e8c0970763d9ab3
https://doi.org/10.1021/bc980086+
https://doi.org/10.1021/bc980086+
Autor:
David L. Ladd, P. Mark Henrichs
Publikováno v:
Synthetic Communications. 28:4143-4149
A procedure for the synthesis of monomethoxypoly(ethylene glycol) aldehydes from monomethoxypoly(ethylene glycol) tosylates is described. The tosylates are converted to aldehydes in high yield via treatment with disodium hydrogen phosphate and DMSO;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5546b8a7ce59b5617fbb4009d7e959bc
https://doi.org/10.1080/00397919809458693
https://doi.org/10.1080/00397919809458693
Autor:
James A. Nelson, Chun Yuan, William B. Eubank, Udo P. Schmiedl, David L. Ladd, Kenneth E. Kellar, Christopher D. V. Black
Publikováno v:
Journal of Magnetic Resonance Imaging. 8:1051-1059
Four rabbits in which atherosclerotic disease was induced by diet and balloon angioplasty underwent conventional angiography and MR angiography (MRA) using a black blood pulse sequence before and 10 minutes after the i.v. injection of a macromolecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d283261d2177709ff3589302ba99a62
https://doi.org/10.1002/jmri.1880080508
https://doi.org/10.1002/jmri.1880080508
Autor:
E. Liversidge, J. L. Toner, J. Shen, Kenneth E. Kellar, David L. Ladd, T.J. Caulfied, C. R. Illig, Jennifer Wellons, P. Guo, N. Peltier
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1657-1662
WIN 70197 is a novel liver-targeted MRI contrast agent. This report describes the efficient synthesis of the chelator along with preliminary NMRD and toxicity data of the gadolinium complex. X-ray diffraction data was used to confirm the predicted ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a5d6dcc3659a9f0a5f50b145863c8c
https://doi.org/10.1016/0960-894x(95)00285-2
https://doi.org/10.1016/0960-894x(95)00285-2
Autor:
Jennifer Wellons, Terry S. Desser, John L. Toner, Qing Fan, David L. Ladd, Kenneth E. Kellar, Holde H. Muller, Stuart W. Young, Robert A. Snow, Daniel L. Rubin
Publikováno v:
Investigative Radiology. 29:S65-S68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a91120623204c0209acabcf3a3f6fbf
https://doi.org/10.1097/00004424-199406001-00022
https://doi.org/10.1097/00004424-199406001-00022
Autor:
T. J. Caulfield, David L. Ladd, Jennifer Wellons, N. Peltier, J. L. Toner, J. Shen, E. Liversidge, P. Guo, C. R. Illig, Kenneth E. Kellar
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7609a40071dcc49bd5e539ee5fa7bf80
https://doi.org/10.1002/chin.199549119
https://doi.org/10.1002/chin.199549119
Autor:
Jill M. Erb, H.-J. Oh, Dennis A. Holt, David L. Ladd, Brian W. Metcalf, Mark Alan Levy, Julie I. Heaslip, Martin Brandt
Publikováno v:
Journal of Medicinal Chemistry. 33:937-942
A series of 17 beta-carbamoyl-1,3,5(10)-estratriene-3-carboxylic acids has been prepared and evaluated in vitro as inhibitors of human and rat prostatic steroid 5 alpha-reductase (EC 1.3.1.30). Potent inhibition of the human enzyme, in particular, wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fd7e3a4e2c6318504a5438d74bfcb1
https://doi.org/10.1021/jm00165a009
https://doi.org/10.1021/jm00165a009
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 12(8)
WIN 22169 is a co-polymer containing approximately 11 repeating units of polyoxyethylene and diethylenetriamine pentaacetic acid (DTPA). WIN 66368, a magnetic resonance imaging (MRI) contrast agent, is the gadolinium III complex of WIN 22169. WIN 221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab6a16d673ccdb6854ab04b1144d016
https://pubmed.ncbi.nlm.nih.gov/7819375
https://pubmed.ncbi.nlm.nih.gov/7819375
Autor:
George Zanazzi, Terry S. Desser, Holde H. Muller, Jennifer Wellons, Samer Khodor, John L. Toner, Fan Qing, Robert A. Snow, David L. Ladd, Daniel L. Rubin, Stuart W. Young, Kenneth E. Kellar
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 4(3)
Macromolecular contrast media offer potential advantages over freely diffusible agents in magnetic resonance (MR) imaging outside the central nervous system. To identify an optimum molecular weight for macromolecular contrast media, the authors studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1933981bde0239729f1022a1ddcb272
https://pubmed.ncbi.nlm.nih.gov/8061449
https://pubmed.ncbi.nlm.nih.gov/8061449