Zobrazeno 1 - 10
of 41
pro vyhledávání: '"David L. Kukis"'
Autor:
Sven H. Hausner, David L. Kukis, M. Karen J. Gagnon, Catherine E. Stanecki, Riccardo Ferdani, John F. Marshall, Carolyn J. Anderson, Julie L. Sutcliffe
Publikováno v:
Molecular Imaging, Vol 8 (2009)
Significant upregulation of the integrin α v β 6 has been described as a prognostic indicator in several cancers, making it an attractive target for tumor imaging. This study compares variants of a PEGylated α v β 6 -targeting peptide, bearing ei
Externí odkaz:
https://doaj.org/article/6f6b4575e93d469e99ad93a943a6c830
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181484 (2017)
Lymphatic dysfunction is associated with the progression of many cardiovascular disorders due to their role in maintaining tissue fluid homeostasis. Promoting new lymphatic vessels (lymphangiogenesis) is a promising strategy to reverse these cardiova
Externí odkaz:
https://doaj.org/article/50c4763515374bdfa3312ba45a65147b
Autor:
Allison L Zwingenberger, Michael S Kent, Ruiwu Liu, David L Kukis, Erik R Wisner, Sally J DeNardo, Sandra L Taylor, Xiucui Chen, Kit S Lam
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34404 (2012)
Theranostic agents are critical for improving the diagnosis and treatment of non-Hodgkin Lymphoma (NHL). The peptidomimetic LLP2A is a novel peptide receptor radiotherapy candidate for treating NHL that expresses the activated α4β1 integrin. Tumor-
Externí odkaz:
https://doaj.org/article/73123107f93440b89c262b35608cb26b
Autor:
David L. Kukis, Douglas J. Rowland, Tyler A. Lesh, A. Kimberley McAllister, Jason Smucny, Melissa D. Bauman, Cynthia M. Schumann, Cameron S. Carter, Simon R. Cherry
Publikováno v:
Translational Psychiatry
Translational psychiatry, vol 9, iss 1
Translational Psychiatry, Vol 9, Iss 1, Pp 1-8 (2019)
Translational psychiatry, vol 9, iss 1
Translational Psychiatry, Vol 9, Iss 1, Pp 1-8 (2019)
Women exposed to a variety of viral and bacterial infections during pregnancy have an increased risk of giving birth to a child with autism, schizophrenia or other neurodevelopmental disorders. Preclinical maternal immune activation (MIA) models are
Autor:
Anthony J. Young, Xin Wang, John D. Lambris, Robert K. Doot, Alice F. Tarantal, David L. Kukis, Edimara S. Reis, Despina Yancopoulou, Nadja Berger, Tetsuhiro Kajikawa, Athena M. Soulika, Dimitrios C. Mastellos, George Hajishengallis, Ranillo R.G. Resuello, Bo Nilsson, Ali Reza Biglarnia, Sophia Koutsogiannaki, Justin T. Gumas, Joel V. Tuplano, Periklis G. Foukas, Markus Huber-Lang
The central component of the complement cascade, C3, is involved in various biological functions, including opsonization of foreign bodies, clearance of waste material, activation of immune cells, and triggering of pathways controlling development. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91837f81fa50edf839efa9faf0ffb86
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-373239
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-373239
Autor:
William A. Mason, Caroline M. Hostetler, Karen L. Bales, Katherine Hinde, David L. Kukis, Sally P. Mendoza, Douglas J. Rowland, Simon R. Cherry, Nicole Maninger, Guobao Wang
Publikováno v:
Hostetler, CM; Hinde, K; Maninger, N; Mendoza, SP; Mason, WA; Rowland, DJ; et al.(2017). Effects of pair bonding on dopamine D1 receptors in monogamous male titi monkeys (Callicebus cupreus). American Journal of Primatology, 79(3), 1-9. doi: 10.1002/ajp.22612. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/27s8p0fm
© 2016 Wiley Periodicals, Inc. Pair bonding leads to increases in dopamine D1 receptor (D1R) binding in the nucleus accumbens of monogamous prairie voles. In the current study, we hypothesized that there is similar up-regulation of D1R in a monogamo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c10f72bbb93965d20d8d13a5a87eee
http://www.escholarship.org/uc/item/27s8p0fm
http://www.escholarship.org/uc/item/27s8p0fm
Publikováno v:
PloS one, vol 12, iss 7
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181484 (2017)
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181484 (2017)
Lymphatic dysfunction is associated with the progression of many cardiovascular disorders due to their role in maintaining tissue fluid homeostasis. Promoting new lymphatic vessels (lymphangiogenesis) is a promising strategy to reverse these cardiova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfac1ac1bacbb92151534e38af347e6c
https://escholarship.org/uc/item/2rk694fp
https://escholarship.org/uc/item/2rk694fp
Autor:
Douglas J. Rowland, Adam T. Austin, Daniel J. Tancredi, Simon R. Cherry, Jill L. Silverman, Yonggang Li, Donald A. Bruun, Brenna M. Flannery, David L. Kukis, Byron D. Ford, Pamela J. Lein, Christopher N. Banks
Publikováno v:
Flannery, BM; Bruun, DA; Rowland, DJ; Banks, CN; Austin, AT; Kukis, DL; et al.(2016). Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication. Journal of Neuroinflammation, 13(1), 267. doi: 10.1186/s12974-016-0744-y. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/73t348st
Journal of neuroinflammation, vol 13, iss 1
Journal of Neuroinflammation
Journal of neuroinflammation, vol 13, iss 1
Journal of Neuroinflammation
BackgroundAcute intoxication with organophosphorus (OP) cholinesterase inhibitors can trigger convulsions that progress to life-threatening status epilepticus. Survivors face long-term morbidity including mild-to-severe decline in memory. It is posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e8eadfe5bc9b502825381952da2ba
http://www.escholarship.org/uc/item/73t348st
http://www.escholarship.org/uc/item/73t348st
Autor:
Karen L. Bales, Aaron L. Smith, Mark M. Goodman, Elizabeth O. Ahlers, Larry J. Young, David H. Abbott, Sara M. Freeman, Todd E. Barnhart, David L. Kukis
Publikováno v:
Bioorganic & medicinal chemistry letters, vol 26, iss 14
Smith, AL; Freeman, SM; Barnhart, TE; Abbott, DH; Ahlers, EO; Kukis, DL; et al.(2016). Initial investigation of three selective and potent small molecule oxytocin receptor PET ligands in New World monkeys. Bioorganic and Medicinal Chemistry Letters, 26(14), 3370-3375. doi: 10.1016/j.bmcl.2016.04.097. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6jk763s9
Smith, AL; Freeman, SM; Barnhart, TE; Abbott, DH; Ahlers, EO; Kukis, DL; et al.(2016). Initial investigation of three selective and potent small molecule oxytocin receptor PET ligands in New World monkeys. Bioorganic and Medicinal Chemistry Letters, 26(14), 3370-3375. doi: 10.1016/j.bmcl.2016.04.097. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6jk763s9
© 2016 Elsevier Ltd The neuropeptide oxytocin is part of a neuroendocrine system that has physiological effects ranging from ensuring uterine myometrial contractions at parturition and post-partum mammary gland milk ejection to the modulation of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e79c29b58a0f98b0a790f4d061fccb
https://escholarship.org/uc/item/6jk763s9
https://escholarship.org/uc/item/6jk763s9
A Novel Method to Label Preformed Liposomes with 64Cu for Positron Emission Tomography (PET) Imaging
Publikováno v:
Bioconjugate Chemistry. 19:2577-2584
Radiolabeling of liposomes with 64Cu (t1/2 = 12.7 h) is attractive for molecular imaging and monitoring drug delivery. A simple chelation procedure, performed at a low temperature and under mild conditions, is required to radiolabel pre-loaded liposo