Zobrazeno 1 - 10
of 209
pro vyhledávání: '"David L. Huso"'
Autor:
Lingling Xian, Dan Georgess, Tait Huso, Leslie Cope, Amy Belton, Yu-Ting Chang, Wenyong Kuang, Qihua Gu, Xiaoyan Zhang, Stefania Senger, Alessio Fasano, David L. Huso, Andrew J. Ewald, Linda M. S. Resar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The function of high mobility group A1 (Hmga1) chromatin remodelling proteins in intestinal stem cells (ISC) is unknown. Here, the authors show that Hmga1 amplifies Wnt/β-catenin signalling to enhance self-renewal and inducesSox9to expand the Paneth
Externí odkaz:
https://doaj.org/article/5e3c00d6fe3d4dd9b4ee8a6610a4fe99
Autor:
Patricia Outeda, David L. Huso, Steven A. Fisher, Marc K. Halushka, Hyunho Kim, Feng Qian, Gregory G. Germino, Terry Watnick
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 634-644 (2014)
Autosomal dominant polycystic kidney disease is a common form of inherited kidney disease that is caused by mutations in two genes, PKD1 (polycystin-1) and PKD2 (polycystin-2). Mice with germline deletion of either gene die in midgestation with a vas
Externí odkaz:
https://doaj.org/article/aa93f166cf0d4e14aabba3dd8b88d730
Autor:
Franck Housseau, Drew M. Pardoll, Cynthia L. Sears, Jaime L. Wolfe, David L. Huso, Shaoguang Wu, Xinqun Wu, Hongni Fan, Abby L. Geis
Mitigation of IL-17 response to ETBF in absence of Tregs is not restricted to CD4+ (Th17) cells.. B6.Foxp3DTR mice were inoculated with ETBF. Either 150 μl purified sterile H2O or 50 ng/g DT was administered ip on days -2, -1, 1, 3, & 5. Colonic LPL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbe3d0ff10e84175289b34cec2a1ae3
https://doi.org/10.1158/2159-8290.22529622.v1
https://doi.org/10.1158/2159-8290.22529622.v1
Autor:
Sonia Franco, Stephen Desiderio, David L. Huso, Tameca Jefferson, Mansi Prakash, Jeremy Chou, Taylor L. Reynolds, Ivana Rybanska-Spaeder
PDF file - 7618K, S1. Analysis of the genetic interaction between 53BP1 and ATM in organismal growth and development. S2. Analysis of ploidy in Trp53bp1-/-/Atm-/- lymphomas. S3. Analysis of Trp53bp1-/-/Atm-/- thymic lymphomas by TCRα/δ locus FISH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31767e5ab37baddd45741c9e34e6f321
https://doi.org/10.1158/1541-7786.22510146.v1
https://doi.org/10.1158/1541-7786.22510146.v1
Autor:
Sonia Franco, Stephen Desiderio, David L. Huso, Tameca Jefferson, Mansi Prakash, Jeremy Chou, Taylor L. Reynolds, Ivana Rybanska-Spaeder
The DNA damage response (DDR) factors ataxia telangiectasia mutated (ATM) and p53 binding protein 1 (53BP1) function as tumor suppressors in humans and mice, but the significance of their mutual interaction to the suppression of oncogenic translocati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909f6f3dc37c7ac20e644f7ac4b433c1
https://doi.org/10.1158/1541-7786.c.6539526
https://doi.org/10.1158/1541-7786.c.6539526
Autor:
Franck Housseau, Drew M. Pardoll, Cynthia L. Sears, Jaime L. Wolfe, David L. Huso, Shaoguang Wu, Xinqun Wu, Hongni Fan, Abby L. Geis
IL-17+ Foxp3+ Tregs infiltrate ETBF-infected colons. Min mice were inoculated with ETBF on day 0. At 10 weeks, colonic LPLs were harvested from colon tumors (left) and adjacent non-tumor colon tissue (right). Cells were stimulated ex vivo, followed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405158293b0979bea222e54801b63450
https://doi.org/10.1158/2159-8290.22529619
https://doi.org/10.1158/2159-8290.22529619
Autor:
Linda M.S. Resar, David L. Huso, Abimbola Aderinto, Brigitte M. Ronnett, Jeanne Kowalski, Joelle Hillion, Francescopaolo Di Cello
Uterine cancer is a common cause for cancer death in women and there is no effective therapy for metastatic disease. Thus, research is urgently needed to identify new therapeutic agents. We showed previously that all female HMGA1a transgenic mice dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d7a0f45d0f30c14e4bfc0d6044f0ab
https://doi.org/10.1158/1535-7163.c.6531089.v1
https://doi.org/10.1158/1535-7163.c.6531089.v1
Autor:
Linda M.S. Resar, David L. Huso, Abimbola Aderinto, Brigitte M. Ronnett, Jeanne Kowalski, Joelle Hillion, Francescopaolo Di Cello
Supplementary Fig from Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac47ffb9975b770c349f617ae5eda888
https://doi.org/10.1158/1535-7163.22483160
https://doi.org/10.1158/1535-7163.22483160
Autor:
Saraswati Sukumar, Manfred Gessler, Goran Landberg, Pedram Argani, Alan Rein, Lionel Feigenbaum, David L. Huso, Scott Kominsky, Soonweng Cho, Weiwen Teo, Preethi Korangath, Nguyen K. Nguyen, Adam Diehl, Liangfeng Han
Supplementary Figure Legends. Legend for Supplementary Figures S1-S10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0f2aad85fe4d577e73d9a3a7b9bc17
https://doi.org/10.1158/0008-5472.22403532.v1
https://doi.org/10.1158/0008-5472.22403532.v1
Autor:
Cynthia L. Sears, Drew M. Pardoll, David L. Huso, Sara Van Meerbeke, Jamunarani S. Vadivelu, April C. Roslani, Ausama A. Malik, Thevambiga Iyadorai, Jane W. Wanyiri, Sudipto Ganguly, Ada Tam, Kellie N. Smith, Nicolas J. Llosa, Xinqun Wu, Hongni Fan, Elizabeth C. Wick, Shaoguang Wu, Franck Housseau
Supplementary Table S4. Histology scores for CD4Stat3-/- and WT (CD4Stat3+/+) C57BL/6 mice colonized 7 days with ETBF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2004423fdcb4db7a279af42f1dfc3e7
https://doi.org/10.1158/0008-5472.22409187.v1
https://doi.org/10.1158/0008-5472.22409187.v1