Zobrazeno 1 - 10
of 89
pro vyhledávání: '"David L. Geenen"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9653 (2023)
Bone marrow-derived mesenchymal stem cells (BM-MSC) are reported to induce beneficial effects in the heart following ischemia, but a loss of these cells within hours of implantation could significantly diminish their long-term effect. We hypothesized
Externí odkaz:
https://doaj.org/article/525b7ad74c3f40538feb341bef8cdca3
Autor:
Robert A. Boomsma, David L. Geenen
Publikováno v:
Stem Cells International, Vol 2014 (2014)
This study examined the interaction of mouse bone marrow mesenchymal stem cells (MSC) with cardiac HL-1 cells during coculture by fluorescent dye labeling and then flow cytometry. MSC were layered onto confluent HL-1 cell cultures in a 1 : 4 ratio. M
Externí odkaz:
https://doaj.org/article/6ba8d21193ff44fd86680a07c1ae5dd3
Publikováno v:
Journal of Developmental Biology, Vol 4, Iss 4, p 32 (2016)
Heart attacks affect more than seven million people worldwide each year. A heart attack, or myocardial infarction, may result in the death of a billion cardiomyocytes within hours. The adult mammalian heart does not have an effective mechanism to rep
Externí odkaz:
https://doaj.org/article/86ed69fe33e74d848f8b61ced3eb5d04
Temporal Expression of Calcium Channel Subunits in Satellite Cells and Bone Marrow Mesenchymal Cells
Publikováno v:
Stem Cell Reviews and Reports. 11:408-422
Bone marrow-derived mesenchymal stem cells (MSC) can be differentiated into myocytes, as well as adipocytes, chondrocytes, and osteocytes in culture. Calcium channels mediate excitation-contraction coupling and are essential for the function of muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a53406708868803d0e15d089aeff37
https://doi.org/10.1007/s12015-014-9566-4
https://doi.org/10.1007/s12015-014-9566-4
Autor:
Laura Bach, Ramaswamy Ramchandran, J. Usha Raj, Aarti Raghavan, David L. Geenen, Qiwei Yang, Miranda Sun
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 307:L537-L544
Pulmonary hypertension (PH) is a chronic disease characterized by a progressive increase in vasomotor tone, narrowing of the vasculature with structural remodeling, and increase in pulmonary vascular resistance. Current treatment strategies include n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f0c240a30f245c7c8a4a0160a8e7d9
https://doi.org/10.1152/ajplung.00093.2014
https://doi.org/10.1152/ajplung.00093.2014
Autor:
Kathrin Banach, Christopher Gans, Nalin M. Kumar, Shwetha Mureli, David L. Geenen, Dan J. Bare
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 304:H600-H609
Mesenchymal stem cells (MSCs) were shown to improve cell survival and alleviate cardiac arrhythmias when transplanted into cardiac tissue; however, little is known about the mechanism by which MSCs modify the electrophysiological properties of cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7652c2f1108ec79077156c4e37034144
https://doi.org/10.1152/ajpheart.00533.2012
https://doi.org/10.1152/ajpheart.00533.2012
Publikováno v:
Journal of Developmental Biology, Vol 4, Iss 4, p 32 (2016)
Journal of Developmental Biology; Volume 4; Issue 4; Pages: 32
Journal of Developmental Biology; Volume 4; Issue 4; Pages: 32
Heart attacks affect more than seven million people worldwide each year. A heart attack, or myocardial infarction, may result in the death of a billion cardiomyocytes within hours. The adult mammalian heart does not have an effective mechanism to rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f565b65d5291c017c706022773d2ac
http://www.mdpi.com/2221-3759/4/4/32
http://www.mdpi.com/2221-3759/4/4/32
Autor:
Beata M. Wolska, R. John Solaro, Milana Grachoff, Chad M. Warren, Shamim A. K. Chowdhury, David L. Geenen, Hsiao Lei Lai, Q. Tian Wang, Farida F. Khan, Andrea McGinley
Publikováno v:
Journal of Molecular and Cellular Cardiology. 53:734-741
During development and differentiation, cell type-specific chromatin configurations are set up to facilitate cell type-specific gene expression. Defects in the establishment or the maintenance of the correct chromatin configuration have been associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9a5e0b091f93ce22af1e41ecb07f40
https://doi.org/10.1016/j.yjmcc.2012.08.014
https://doi.org/10.1016/j.yjmcc.2012.08.014
Publikováno v:
Journal of Molecular and Cellular Cardiology. 53:382-391
Our aim was to further elucidate the cardiac lineage development of bone marrow-derived mesenchymal stem cells (MSC) and to identify cells which had the potential for cardiac myogenic differentiation when compared to skeletal muscle satellite (Sk-sat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d666276b11ab11e41e8bd0d05fa4723e
https://doi.org/10.1016/j.yjmcc.2012.06.003
https://doi.org/10.1016/j.yjmcc.2012.06.003
Autor:
R.D. Minshall, Dan J. Bare, Beata M. Wolska, Kathrin Banach, Iurii Semenov, David L. Geenen, Jaime DeSantiago
Publikováno v:
Journal of Molecular and Cellular Cardiology. 52:1249-1256
In clinical trials mesenchymal stem cells (MSCs) are transplanted into cardiac ischemic regions to decrease infarct size and improve contractility. However, the mechanism and time course of MSC-mediated cardioprotection are incompletely understood. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69346dc575cea033c36aef1db40af8c8
https://doi.org/10.1016/j.yjmcc.2012.03.008
https://doi.org/10.1016/j.yjmcc.2012.03.008