Zobrazeno 1 - 10
of 76
pro vyhledávání: '"David L. Gasser"'
Autor:
Min Peng, Marni J Falk, Volker H Haase, Rhonda King, Erzsebet Polyak, Mary Selak, Marc Yudkoff, Wayne W Hancock, Ray Meade, Ryoichi Saiki, Adam L Lunceford, Catherine F Clarke, David L Gasser
Publikováno v:
PLoS Genetics, Vol 4, Iss 4, p e1000061 (2008)
Coenzyme Q (CoQ) is an essential electron carrier in the respiratory chain whose deficiency has been implicated in a wide variety of human mitochondrial disease manifestations. Its multi-step biosynthesis involves production of polyisoprenoid diphosp
Externí odkaz:
https://doaj.org/article/4b0727f4f27f4e6eb1b2ffd376c6dd98
Autor:
Jasmine Chong, Hoon Ki Sung, Assaf Ben-Meir, Ellen Wong, Robert F. Casper, James Meriano, David L. Gasser, Kelle H. Moley, Andrea Jurisicova, Siegfried Hekimi, Tetyana Yavorska, Aluet Borrego‐Alvarez, Taline Naranian, Yaakov Bentov, Eliezer Burstein, Jennifer Alexis, Ying Wang, Maggie M.-Y. Chi
Publikováno v:
Aging Cell
Female reproductive capacity declines dramatically in the fourth decade of life as a result of an age-related decrease in oocyte quality and quantity. The primary causes of reproductive aging and the molecular factors responsible for decreased oocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df5d25977b4fb862c710579ba24ee35
http://europepmc.org/articles/PMC4568976
http://europepmc.org/articles/PMC4568976
Autor:
Mai Tsukikawa, Young Joon Kwon, Jeff D. Thomas, Joseph Licata, Zhe Zhang, Eric Marty, Rui Xiao, Carolyn A. Felix, Min Peng, David L. Gasser, Yair Argon, Julian Ostrovsky, Erzsebet Polyak, Marni J. Falk
Mitochondrial respiratory chain (RC) disease therapies directed at intra-mitochondrial pathology are largely ineffective. Recognizing that RC dysfunction invokes pronounced extra-mitochondrial transcriptional adaptations, particularly involving dysre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddb89ac22266d6e4cf94bb5efb51b7a
https://europepmc.org/articles/PMC4527487/
https://europepmc.org/articles/PMC4527487/
Publikováno v:
Journal of the American Society of Nephrology. 16:2847-2851
Collapsing glomerulopathy (CG) is associated with disorders that markedly perturb the phenotype of podocytes. The kd/kd mouse has been studied for immune and genetic causes of microcystic tubulointerstitial nephritis with little attention to its glom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fba8b8c456d653758ada979ca8fd94
https://doi.org/10.1681/asn.2005050494
https://doi.org/10.1681/asn.2005050494
Autor:
Rexford S. Ahima, Min Peng, Wayne W. Hancock, Ray Meade, Daniel J. Rader, John E. Tomaszewski, Michael P. Madaio, David L. Gasser, Alberto Mendoza
Publikováno v:
American Journal of Nephrology. 25:604-610
Background/Aim: The kd/kd mouse spontaneously develops severe and progressive nephritis leading to renal failure, characterized by cellular infiltration, tubular destruction and glomerular sclerosis. Recent identification of the mutant gene and the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4774d3ef934bc6314506d4976baa3f42
https://doi.org/10.1159/000089709
https://doi.org/10.1159/000089709
Autor:
Melvin R. Hayden, Natan Cohen, Andrea Galassi, Pamela Schinleber, Marco Antonio P. Leite, David L. Gasser, Michael Rapoport, Hongqi Ren, Shai Efrati, Daniel J. Rader, Zhihong Liu, Barry I. Freedman, Laurie Roberts, David Modai, Wayne W. Hancock, James R. Sowers, Ahuva Golik, Federica Cecchini, Jin Kim, Caihong Zeng, Frederic Clayton, John E. Tomaszewski, Krystyna Pawlak, Joshua Weissgarten, Renata C. Santos, In San Kim, Leishi Li, Cristianne L. Fabris, Michael P. Madaio, Jung Ho Cha, Huiping Chen, Adam Whaley-Connell, Walid Ghantous, James M. Bates, Guillermo Coca Velarde, Can Li, Stuart M. Sprague, Min Peng, Vernon L. Tesh, Chul Woo Yang, Claudine Jurkovitz, F.M. Ribeiro, William M. McClellan, Michal Mysliwiec, Jolanta Malyszko, Hajamohideen S. Raffi, Mordechay Aladjem, Guang Yang, Jacek S. Malyszko, Donald E. Kohan, Nataliya V. Volkova, Domenico Russo, Satish Kumar, Zoltan Laszik, Jocemir Ronaldo Lugon, Olivia Turri, Suk Hee Lee, Alberto Mendoza, Ray Meade, Elena Galperin, Scott G. Satko, Nathaniel D. Denkers, J. Michael Soucie, Rexford S. Ahima, Maria Luisa Biondi, Tomasz Hryszko, Anna L. Zisman, Fletcher B. Taylor, Richard L. Siegler, Sun Woo Lim, Bum Soon Choi, Theodore J. Pysher, Vittorio E. Andreucci, Hong Zhou, Maurizio Gallieni, Jenna Krisher, Diego Brancaccio, Mario Cozzolino, Sylvia Berman, Zhan Averbukh, Randall Lou, Zheng Tang
Publikováno v:
American Journal of Nephrology. 25:627-630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd57c9798dcabc871200418ce3daa8a
https://doi.org/10.1159/000090454
https://doi.org/10.1159/000090454
Publikováno v:
The Journal of Immunology. 171:2778-2781
The kidney disease (kd) mutation was transferred to a C57BL/6 (B6) background by selection for closely linked microsatellite markers. The resulting congenic strain, B6.kd, was mated with partners homozygous for targeted mutations of CD4, CD8, CD28, I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f29b9176090d2cc22904f8648004747
https://doi.org/10.4049/jimmunol.171.6.2778
https://doi.org/10.4049/jimmunol.171.6.2778
Publikováno v:
Mammalian Genome. 11:967-971
Mice that are homozygous for the kidney disease (kd) gene on Chromosome (Chr) 10 spontaneously develop a progressive and fatal interstitial nephritis. The disease phenotype is similar to that of the human disease, juvenile nephronophthisis. Using a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97f6a5f3aa6a30f1dae9e4cad0214f9
https://doi.org/10.1007/s003350010188
https://doi.org/10.1007/s003350010188
Publikováno v:
Biochemical Genetics. 38:337-340
The kidney disease (kd) mutation arose spontaneously in the CBA/CaH inbred mouse strain and is transmitted as an autosomal recessive trait (Lyon and Hulse, 1971). CBA/CaH-kd/kd mice die at 5 to 7 months with inanition, a urinary concentrating defect,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a22a7dc9b6a47ea497e1fbb89a8ce6
https://doi.org/10.1023/a:1002013218535
https://doi.org/10.1023/a:1002013218535
Autor:
Nandita Quaderi, Andrea Ballabio, Brunella Franco, Eugenio Montini, Bärbel Wittwer, George J. Feldman, Erich Roessler, John M. Opitz, David L. Gasser, Karin Gaudenz, Maximilian Muenke
Publikováno v:
The American Journal of Human Genetics. 63:703-710
Summary The MID1 gene in Xp22 codes for a novel member of proteins containing a RING finger, B-box, coiled-coil and a conserved C-terminal domain. Initially, three mutations in the C-terminal region were found in patients with Opitz G/BBB syndrome, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47efbcde2e0b33f298c5242539da59b
https://doi.org/10.1086/302010
https://doi.org/10.1086/302010