Zobrazeno 1 - 10
of 151
pro vyhledávání: '"David L. Eaton"'
Autor:
Lisa A McConnachie, Dianne Botta, Collin C White, Chad S Weldy, Hui-Wen Wilkerson, Jianbo Yu, Russell Dills, Xiaozhong Yu, William C Griffith, Elaine M Faustman, Federico M Farin, Sean E Gill, William C Parks, Xiaoge Hu, Xiaohu Gao, David L Eaton, Terrance J Kavanagh
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64165 (2013)
Quantum dots (QDs) are unique semi-conductor fluorescent nanoparticles with potential uses in a variety of biomedical applications. However, concerns exist regarding their potential toxicity, specifically their capacity to induce oxidative stress and
Externí odkaz:
https://doaj.org/article/9a66621ea2f245768acf5d449fa78fac
Autor:
Diana Dow-Edwards, Leslie Y. Kwan, Edward D. Levin, John C. Talpos, David L. Eaton, Charles V. Vorhees, Abby A. Li, Susan L. Andersen
Publikováno v:
Neurotoxicology and teratology. 81
Response variability across the lifespan is an important consideration in toxicology and risk assessment, and the toxic effects of drugs and chemicals during adolescence need more research. This paper summarizes a workshop presented in March 2019, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6b40524a0821f318f1b4d90fc45f98
https://pubmed.ncbi.nlm.nih.gov/32698050
https://pubmed.ncbi.nlm.nih.gov/32698050
Autor:
Gideon St.Helen, David L. Eaton
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c142b2f4a236577f7bc18abc14926dfd
https://europepmc.org/articles/PMC6260959/
https://europepmc.org/articles/PMC6260959/
Autor:
National Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Population Health and Public Health Practice, Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems, David L. Eaton, Leslie Y. Kwan, Kathleen Stratton
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxi
Autor:
David Ozonoff, Bernhard Hennig, Raina M. Maier, Robert H. Tukey, Bernard D. Goldstein, Robert O. Wright, José F. Cordero, Martyn T. Smith, David L. Eaton, Philip J. Landrigan
Publikováno v:
Environmental Health Perspectives
Background The Superfund Research Program (SRP) is an academically based, multidisciplinary, translational research program that for 25 years has sought scientific solutions to health and environmental problems associated with hazardous waste sites.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e17834c705673d8b9fa50fa8f7cb2de
http://europepmc.org/articles/PMC4590764
http://europepmc.org/articles/PMC4590764
Autor:
Joanne Wang, Chunying Gao, Thomas A. Rosenquist, David L. Eaton, Thomas Neumann, Catherine K. Yeung, Qingcheng Mao, Elijah J. Weber, Jonathan Himmelfarb, Arthur P. Grollman, Kathleen G. Dickman, Edward J. Kelly, Shih-Yu Chang, Viktoriya S. Sidorenko, Danny D. Shen, Alenka Chapron
Publikováno v:
JCI Insight. 2
Environmental exposures pose a significant threat to human health. However, it is often difficult to study toxicological mechanisms in human subjects due to ethical concerns. Plant-derived aristolochic acids are among the most potent nephrotoxins and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8a406bc66358c7c1305c32fa8f7f6b
https://doi.org/10.1172/jci.insight.95978
https://doi.org/10.1172/jci.insight.95978
Autor:
Kirk P. Van Ness, Edward J. Kelly, David L. Eaton, Elijah J. Weber, Shih-Yu Chang, Danielle Zumpano
Publikováno v:
Current Protocols in Toxicology
The liver and the kidney are key toxicity target organs during drug development campaigns, as they typically carry the burden of drug transport and metabolism. Primary hepatocytes and proximal tubule epithelial cells grown in traditional in vitro 2-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3d434fc5c96e8b4120f7bcf4ad2efb
https://pubmed.ncbi.nlm.nih.gov/28777442
https://pubmed.ncbi.nlm.nih.gov/28777442
Autor:
David L. Eaton, Christopher M. Schaupp
Publikováno v:
Cancer Prevention Research. 7:653-657
In this issue, Johnson and colleagues provide a remarkable demonstration of the potential for “chemoprevention” of cancer from mutagenic chemicals. The authors demonstrated complete protection of rats from a carcinogenic treatment regimen with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aea79901231fef966c2e254acad35b9
https://doi.org/10.1158/1940-6207.capr-14-0119
https://doi.org/10.1158/1940-6207.capr-14-0119
Autor:
Xiaohu Gao, William C. Griffith, Vivian Lee, William C. Parks, Terrance J. Kavanagh, Elaine M. Faustman, John K. McGuire, Ryan S. McMahan, Xiaoge Hu, David L. Eaton
Publikováno v:
Nanotoxicology. 9:336-343
Quantum dots (Qdots) are semiconductor nanoparticles with size-tunable fluorescence capabilities with diverse applications. Qdots typically contain cadmium or other heavy metals, hence raising concerns of their potential toxicity, especially in occup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fa6e1000fb1a5f10fdf8bcb862d355
https://doi.org/10.3109/17435390.2014.930532
https://doi.org/10.3109/17435390.2014.930532
Autor:
Emma Jane Poulton, Kenneth E. Thummel, Danny D. Shen, Johanna W. Lampe, Margaret C. Shuhart, Leslie J. Dickmann, Zhican Wang, David L. Eaton, Connie L. Davis, Yvonne S. Lin
Publikováno v:
Journal of Bone and Mineral Research. 28:1101-1116
Long-term therapy with certain drugs, especially cytochrome P450 (P450; CYP)-inducing agents, confers an increased risk of osteomalacia that is attributed to vitamin D deficiency. Human CYP24A1, CYP3A4, and CYP27B1 catalyze the inactivation and activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba43f4da9990ec745c6706ce70bf3b2
https://doi.org/10.1002/jbmr.1839
https://doi.org/10.1002/jbmr.1839