Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David L. Downie"'
Autor:
Pamela S. Chasek, David L. Downie
Publikováno v:
Global Environmental Politics ISBN: 9780429276743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd426255a677606db0d830364c172e13
https://doi.org/10.4324/9780429276743-1
https://doi.org/10.4324/9780429276743-1
Autor:
Pamela S. Chasek, David L. Downie
Publikováno v:
Global Environmental Politics ISBN: 9780429276743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6be0ab2ae6611ae1b40bcc16e529567
https://doi.org/10.4324/9780429276743-6
https://doi.org/10.4324/9780429276743-6
Autor:
Pamela S. Chasek, David L. Downie
Publikováno v:
Global Environmental Politics ISBN: 9780429276743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441c995bb558734a83d48383af165a08
https://doi.org/10.4324/9780429276743-2
https://doi.org/10.4324/9780429276743-2
Autor:
Pamela S. Chasek, David L. Downie
Publikováno v:
Global Environmental Politics ISBN: 9780429276743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be53b83115b2f2f037e21ee12faacb02
https://doi.org/10.4324/9780429276743-4
https://doi.org/10.4324/9780429276743-4
Autor:
Pamela Chasek, David L. Downie
Global Environmental Politics has provided an accurate, up-to-date, and unbiased understanding of the world's most pressing environmental issues for thirty years. The eighth edition continues this practice by covering critical new developments in glo
Autor:
Andrew J. Powell, Michael J. Carr, Dramane I. Laine, Stacey L. Walsh, Emma Ward, David L. Downie, Derek J. Trezise, Mao Xiang Chen, Helen F. Sneddon, Kelly M Gatfield
Publikováno v:
SLAS Discovery. 20:242-253
The epithelial sodium channel (ENaC) plays a crucial role in salt and water homeostasis and is primarily involved in sodium reabsorption in the kidney and lung. Modulators of ENaC function, particularly within lung epithelia, could offer potential tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c9416849ea51ecc11f779908cfe7ae
https://doi.org/10.1177/1087057114552399
https://doi.org/10.1177/1087057114552399
Autor:
Pamela Brown, Roger Edward Markwell, David L. Downie, Susanne Eyrisch, Neil D. Pearson, Dongzhao Chen, Christopher Barfoot, Stephen Rittenhouse, Graham Elgin Jones, Mark A. Seefeld, Elizabeth A. Minthorn, Jeffrey M. Axten, Steven Dabbs, Alan Joseph Hennessy, Michael N. Gwynn, Gerald Brooks, Jianzhong Huang, Ilaria Giordano, William H. Miller, David T. Davies, Timothy Francis Gallagher, Timothy J. Miles, Jennifer Hoover
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:7489-7495
We have identified a series of amino-piperidine antibacterials with a good broad spectrum potency. We report the investigation of various subunits in this series and advanced studies on compound 8. Compound 8 possesses good pharmacokinetics, broad sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c89d8d5098d1fe72b99b9bbcc372d3c
https://doi.org/10.1016/j.bmcl.2011.09.117
https://doi.org/10.1016/j.bmcl.2011.09.117
Autor:
Stephen Rittenhouse, Neil D. Pearson, Christopher Barfoot, Graham Elgin Jones, Timothy J. Miles, David L. Downie, Dongzhao Chen, Steven Dabbs, Jennifer Hoover, Roger Edward Markwell, Alan Joseph Hennessy, Jianzhong Huang, Michael N. Gwynn, Ilaria Giordano, Gerald Brooks, Hong Xiang, David T. Davies, Susanne Eyrisch, Pamela Brown
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:7483-7488
As part of our wider efforts to exploit novel mode of action antibacterials, we have discovered a series of cyclohexyl-amide compounds that has good Gram positive and Gram negative potency. The mechanism of action is via inhibition of bacterial topoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3810e692448006878f359f5ce7432ed6
https://doi.org/10.1016/j.bmcl.2011.09.114
https://doi.org/10.1016/j.bmcl.2011.09.114
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 12:96-106
The tractability of ion channels as drug targets has been significantly improved by the advent of planar array electrophysiology platforms which have dramatically increased the capacity for electrophysiological profiling of lead series compounds. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8399c811f16a1cbcac33ae65db0e076b
https://doi.org/10.2174/138620709787048000
https://doi.org/10.2174/138620709787048000