Monitoring dynamic spiculation in red blood cells with scanning ion conductance microscopy

Autor: Lane A. Baker, Wenqing Shi, Cheng Zhu, David L. Daleke

Publikováno v: The Analyst. 143:1087-1093

Phospholipids are critical structural components of the membrane of human erythrocytes and their asymmetric transbilayer distribution is essential for normal cell functions. Phospholipid asymmetry is maintained by transporters that shuttle phospholip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af40d1a0f9fd12b556b8481cfa826c90
https://doi.org/10.1039/c7an01986f

The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2:A phosphatidylserine flippase

Autor: Michael G. Palmgren, David L. Daleke, Kristina Faxén, Thomas Günther Pomorski, Gunnar Dittmar, Jürgen Schiller, Danny Mollerup Sørensen, Lisa Theorin, Rebekka Migotti, Rosa L. López-Marqués

Publikováno v: Theorin, L, Faxén, K, Sørensen, D M, Migotti, R, Dittmar, G, Schiller, J, Daleke, D L, Palmgren, M, López-Marqués, R L & Pomorski, T G 2019, ' The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2 : A phosphatidylserine flippase ', Biochemical Journal, vol. 476, no. 5, pp. 783-794 . https://doi.org/10.1042/BCJ20180891
Biochemical Journal

Type IV P-type ATPases (P4 ATPases) are lipid flippases that catalyze phospholipid transport from the exoplasmic to the cytoplasmic leaflet of cellular membranes, but the mechanism by which they recognize and transport phospholipids through the lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cb818aff1f870ec4f6b2bcedb4be38
https://curis.ku.dk/portal/da/publications/the-lipid-head-group-is-the-key-element-for-substrate-recognition-by-the-p4-atpase-ala2(961d07d8-bc76-4594-b802-c4a1537bb5b0).html

The Yeast Plasma Membrane ATP Binding Cassette (ABC) Transporter Aus1

Autor: Peter Müller, David L. Daleke, Magdalena Marek, Gunnar Dittmar, Gabriele Schreiber, Andreas Herrmann, Sigrid Milles, Thomas Güenther Pomorski

Publikováno v: Journal of Biological Chemistry. 286:21835-21843

The ATP binding cassette (ABC) transporter Aus1 is expressed under anaerobic growth conditions at the plasma membrane of the yeast Saccharomyces cerevisiae and is required for sterol uptake. These observations suggest that Aus1 promotes the transloca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::679408cdae168b34a51b907efb846e94
https://doi.org/10.1074/jbc.m111.244525

ATP-Dependent Transport of Phosphatidylserine Analogues in Human Erythrocytes

Autor: Smriti, David L. Daleke, Edward C. Nemergut

Publikováno v: Biochemistry. 46:2249-2259

The plasma membrane of most cells contains a number of lipid transporters that catalyze the ATP-dependent movement of phospholipids across the membrane and assist in the maintenance of lipid asymmetry. The most well-characterized of these transporter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da34cbd13934c7bee4bdfb23f720c1f0
https://doi.org/10.1021/bi061333x

Lipid Specific Activation of the Murine P4-ATPase Atp8a1 (ATPase II)

Autor: Margaret S. Halleck, Jill Paterson, Patrick Williamson, Robert A. Schlegel, Kathleen Renkema, David L. Daleke, Lisa Burden

Publikováno v: Biochemistry. 45:5367-5376

The asymmetric transbilayer distribution of phosphatidylserine (PS) in the mammalian plasma membrane and secretory vesicles is maintained, in part, by an ATP-dependent transporter. This aminophospholipid "flippase" selectively transports PS to the cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a555b443d27e3713cc9e3433297dbef8
https://doi.org/10.1021/bi052359b