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pro vyhledávání: '"David L. Conine"'
Publikováno v:
Toxicology and Applied Pharmacology. 37:445-453
Male Wistar rats in groups of six to eight received a single ip injection of sodium pentafluorostannite (NaSn2F5), 9.4 mg of F/kg; sodium fluoride (NaF), 9.4 mg of F/kg; or distilled water. In the first two studies, one in post-treatment fed rats and
Publikováno v:
Toxicology and Applied Pharmacology. 35:21-28
For 30 days, groups of 12–19 Wistar rats (divided according to sex) were dosed daily by gavage with distilled water or with 20, 100, or 175 mg/kg sodium pentafluorostannite. On Days 14 and 29, blood was collected from five rats in each group to det
Autor:
Joseph C. Muhler, Robert B. Forney, David L. Conine, George K. Stookey, Robert Martz, Moonahm Yum
Publikováno v:
Toxicology and Applied Pharmacology. 33:21-26
The toxicity of sodium pentafluorostannite (NaSn2F5) in mice and rats has been investigated. LD50 values in mice were 18.9, 80.9, and 592.9 mg/kg in fed mice dosed iv, ip, and po, respectively. Signs of toxicity in mice included ataxia, muscle weakne
Publikováno v:
Toxicology and Applied Pharmacology. 37:363-370
Rat kidneys were studied with light and electron microscopy 12 hr, 24 hr, 4 days, and 14 days after the rats had received a single ip injection of NaSn 2 F 5 (35.0 mg/kg), NaF (20.7 mg/kg), or SnCl 2 · 2H 2 O (44.4 mg/kg). Rats receiving NaSn 2 F 5