Zobrazeno 1 - 10
of 92
pro vyhledávání: '"David L. Boone"'
Autor:
Anne-Marie C. Overstreet, Bernadette E. Grayson, Antonia Boger, Danika Bakke, Erin M. Carmody, Cayla E. Bales, Shirley C. Paski, Stephen F. Murphy, Christopher R. Dethlefs, Kara J. Shannon, Katie R. Adlaka, Claire E. Wolford, Vincent J. Campiti, Christina V. Raghunandan, Randy J. Seeley, David L. Boone
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Obesity and its sequelae have a major impact on human health. The stomach contributes to obesity in ways that extend beyond its role in digestion, including through effects on the microbiome. Gastrokine-1 (GKN1) is an anti-amyloidogenic prot
Externí odkaz:
https://doaj.org/article/e0898e43e9d842fda58154164588cbbb
Autor:
Felipe Melo-González, Javiera Sepúlveda-Alfaro, Bárbara M. Schultz, Isidora D. Suazo, David L. Boone, Alexis M. Kalergis, Susan M. Bueno
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Infectious diseases are one of the leading causes of morbidity and mortality worldwide, affecting high-risk populations such as children and the elderly. Pathogens usually activate local immune responses at the site of infection, resulting in both pr
Externí odkaz:
https://doaj.org/article/07dd0390b15d437aa6354db20ee12221
Autor:
Jin Wan Kim, Tariq J. Dayah, Awad Javaid, Dominique J. Monlezun, Dinu V. Balanescu, Teodora Donisan, Kaveh Karimzad, Abdul Hakeem, David L. Boone, Nicolas Palaskas, Juan Lopez-Mattei, Peter Y. Kim, Jean-Bernard Durand, Juhee Song, Serban M. Balanescu, Eric H. Yang, Joerg Herrmann, Konstantinos Marmagkiolis, Konstantinos Toutouzas, Nils P. Johnson, Cezar A. Iliescu
Publikováno v:
Medicina, Vol 58, Iss 7, p 884 (2022)
Background and Objectives: Cancer and coronary artery disease (CAD) often coexist. Compared to quantitative coronary angiography (QCA), fractional flow reserve (FFR) has emerged as a more reliable method of identifying significant coronary stenoses.
Externí odkaz:
https://doaj.org/article/db24a0e319144151b1959a470054112f
Autor:
Emilio Boada-Romero, Inmaculada Serramito-Gómez, María P. Sacristán, David L. Boone, Ramnik J. Xavier, Felipe X. Pimentel-Muiños
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The T300A substitution in ATG16L is associated with Crohn’s disease risk and disrupts clearance of intracellular pathogens by autophagy. Here the authors show that the mutation impairs interaction of ATG16L with TMEM59 and disrupts unconventional T
Externí odkaz:
https://doaj.org/article/34956e407de4444e99fd297358803333
Autor:
Alvaro Torres-Huerta, Katelyn Ruley-Haase, Theodore Reed, Antonia Boger-May, Derek Rubadeux, Lauren Mayer, Arpitha Mysore Rajashekara, Morgan Hiller, Madeleine Frech, Connor Roncagli, Cameron Pedersen, Mary Catherine Camacho, Lauren Hollmer, Lauren English, Grace Kane, David L Boone
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300892 (2024)
Inflammatory bowel diseases (IBD) result from uncontrolled inflammation in the intestinal mucosa leading to damage and loss of function. Both innate and adaptive immunity contribute to the inflammation of IBD and innate and adaptive immune cells reci
Externí odkaz:
https://doaj.org/article/c279009d899749449268a580450f91fb
Autor:
David L. Boone, Benjamin K. Tsang
Publikováno v:
BioTechniques, Vol 22, Iss 4, Pp 648-649 (1997)
Externí odkaz:
https://doaj.org/article/6cc64f5a12694204ab48b21ae9945072
Autor:
Grace A Taylor, David L. Boone, Matthew R. Olson, Maia G Clare, D. Alejandro Canaria, Majid Kazemian, Bingyu Yan, Zonghao Zhang
Publikováno v:
J Immunol
IL-9–producing Th cells, termed Th9 cells, contribute to immunity against parasites and cancers but have detrimental roles in allergic disease and colitis. Th9 cells differentiate in response to IL-4 and TGF-β, but these signals are insufficient t
Autor:
Christopher R. Dethlefs, Vincent J Campiti, Antonia Boger, Bernadette E. Grayson, Shirley C Paski, David L. Boone, Kara J. Shannon, Stephen F. Murphy, Anne-Marie C. Overstreet, Christina V. Raghunandan, Cayla E. Bales, Katie R. Adlaka, Danika Bakke, Erin M. Carmody, Claire E. Wolford, Randy J. Seeley
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Obesity and its sequelae have a major impact on human health. The stomach contributes to obesity in ways that extend beyond its role in digestion, including through effects on the microbiome. Gastrokine-1 (GKN1) is an anti-amyloidogenic protein abund
Autor:
Tova Wasserman-Bruck, Boger-May Boger-May, Derek Rubadeux, Katelyn Ruley-Haase, David L. Boone
Publikováno v:
Proceedings of IMPRS. 4
Background and Objectives: Gastrokine-1 (Gkn1) is a protein produced solely in the stomach and secreted into the lumen of the gut. Gkn1 has a BRICHOS domain which is anti-amyloidogenic. While the exact function of Gkn1 is not yet completely understoo
Autor:
Robert V. Stahelin, Michael D. Pluth, Ines Batinic-Haberle, Yan Gao, Karl D Straubg, David L. Boone, Andrea K. Steiger, Charles R. Tessier, Kenneth R. Olson, Troy A. Markel
Publikováno v:
Molecules
Molecules, Vol 25, Iss 4, p 980 (2020)
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 980 (2020)
Volume 25
Issue 4
Manganese porphyrins (MnPs), MnTE-2-PyP5+, MnTnHex-2-PyP5+ and MnTnBuOE-2-PyP5+, are superoxide dismutase (SOD) mimetics and form a redox cycle between O2 and reductants, including ascorbic acid, ultimately producing hydrogen peroxide (H2O2). We prev