Zobrazeno 1 - 10
of 237
pro vyhledávání: '"David L Williamson"'
Autor:
Bradley Carrier, Shin Wen, Sophia Zigouras, Richard W Browne, Zhuyun Li, Mulchand S Patel, David L Williamson, Todd C Rideout
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90863 (2014)
We characterized the hypolipidemic effects of alpha-lipoic acid (LA, R-form) and examined the associated molecular mechanisms in a high fat fed Zucker rat model. Rats (n = 8) were assigned to a high fat (HF) diet or the HF diet with 0.25% LA (HF-LA)
Externí odkaz:
https://doaj.org/article/fae6a5f476f648f984643122fc501fdc
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6302 (2009)
Inhibitor of differentiation protein-2 (Id2) is a dominant negative helix-loop-helix (HLH) protein, and a positive regulator of proliferation, in various cells. The N-terminal region of Id2 contains a consensus cdk2 phosphorylation sequence SPVR, whi
Externí odkaz:
https://doaj.org/article/8f1db064f66041c296181d7c63672129
Autor:
Alec B. Chaves, Edwin R. Miranda, Jacob T. Mey, Brian K. Blackburn, Kelly N. Z. Fuller, Blaise Stearns, Andrew Ludlow, David L. Williamson, Joseph A. Houmard, Jacob M. Haus
Publikováno v:
J Appl Physiol (1985)
Thioredoxin-interacting protein (TXNIP) negatively effects the redox state and growth signaling via its interactions with thioredoxin (TRX) and regulated in development and DNA damage response 1 (REDD1), respectively. TXNIP expression is downregulate
Publikováno v:
Analytical chemistry. 94(6)
Herein, we report on the experimental measurements for estimated relative mobility shifts caused by changes in mass distribution from isotopic substitutions in isotopologues and isotopomers with high-resolution cyclic ion mobility separations. By uti
Autor:
William P. Miller, Allyson L. Toro, Siddharth Sunilkumar, Shaunaci A. Stevens, Ashley M. VanCleave, David L. Williamson, Alistair J. Barber, Michael D. Dennis
Publikováno v:
Diabetes. 71(5)
Clinical studies support a role for the protein regulated in development and DNA damage response 1 (REDD1) in ischemic retinal complications. To better understand how REDD1 contributes to retinal pathology, we examined human single-cell sequencing da
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32(10)
In high-resolution ion mobility spectrometry-mass spectrometry (IMS-MS)-based separations individual, pure, oligosaccharide species often produce multiple IMS peaks presumably from their α/β anomers, cation attachment site conformations, and/or oth
Autor:
G Campoy, Xavier Gasull, Elena Feinstein, Joan Romaní-Aumedes, David L. Williamson, Leticia Pérez-Sisqués, Núria Martín-Flores, J Solana, Sara Fernández-García, H-Y Man, Manuel J. Rodriguez, Esther García-García, Artur Llobet, Mercè Masana, Jordi Alberch, Mercè Canal, JP Gilbert, Nuria Sánchez-Fernández, David Soto, Cristina Malagelada
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Background RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death in in vitro and in vivo models of Parkinson's and Huntington's diseases and is up regulated in compromised neurons in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b735542b9f3d11f5a5b7c7adb12480
http://hdl.handle.net/2445/177519
http://hdl.handle.net/2445/177519
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 11, Iss 5, Pp 1309-1328 (2019)
A closed total energy (TE) budget is of utmost importance in coupled climate system modeling; in particular, the dynamical core or physics‐dynamics coupling should ideally not lead to spurious TE sources/sinks. To assess this in a global climate mo
Publikováno v:
Journal of Lipids, Vol 2013 (2013)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a novel biomarker of LDL clearance and a therapeutic target of cardiovascular disease. We examined the effects of aerobic exercise training in modulating PCSK9 abundance and hepatic sterol regu
Externí odkaz:
https://doaj.org/article/6d6e2ea1d8fa49edb4671bb91729dde6
Autor:
Robert C. Hickner, Jennifer L. Steiner, Bradley S. Gordon, David L. Williamson, Bonde R. Johnson, Michael J. Ormsbee
Publikováno v:
Acta physiologica (Oxford, England)REFERENCES. 231(1)
Exercise is a key component of a healthy lifestyle as it helps maintain a healthy body weight and reduces the risk of various morbidities and co-morbidities. Exercise is an acute physiological stress that initiates a multitude of processes that attem