Zobrazeno 1 - 10
of 209
pro vyhledávání: '"David L Perkins"'
Autor:
Yi-Shin Chang, Kai Huang, Jessica M Lee, Christen L Vagts, Christian Ascoli, Md-Ruhul Amin, Mahmood Ghassemi, Claudia M Lora, Russell Edafetanure-Ibeh, Yue Huang, Ruth A Cherian, Nandini Sarup, Samantha R Warpecha, Sunghyun Hwang, Rhea Goel, Benjamin A Turturice, Cody Schott, Montserrat Hernandez, Yang Chen, Julianne Jorgensen, Wangfei Wang, Mladen Rasic, Richard M Novak, Patricia W Finn, David L Perkins
Publikováno v:
eLife, Vol 13 (2024)
Background: End-stage renal disease (ESRD) patients experience immune compromise characterized by complex alterations of both innate and adaptive immunity, and results in higher susceptibility to infection and lower response to vaccination. This immu
Externí odkaz:
https://doaj.org/article/7079f825a3dd43fd8ab53c2f324b6355
Autor:
Kai Huang, Catherine Wang, Christen Vagts, Vanitha Raguveer, Patricia W Finn, David L Perkins
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0261242 (2022)
Hyperactive and damaging inflammation is a hallmark of severe rather than mild Coronavirus disease 2019 (COVID-19). To uncover key inflammatory differentiators between severe and mild COVID-19, we applied an unbiased single-cell transcriptomic analys
Externí odkaz:
https://doaj.org/article/4240d2e639d04e45a311372832af5065
Autor:
Benjamin A Turturice, Juliana Theorell, Mary Dawn Koenig, Lisa Tussing-Humphreys, Diane R Gold, Augusto A Litonjua, Emily Oken, Sheryl L Rifas-Shiman, David L Perkins, Patricia W Finn
Publikováno v:
eLife, Vol 10 (2021)
There are perinatal characteristics, such as gestational age, reproducibly associated with the risk for pediatric asthma. Identification of biologic processes influenced by these characteristics could facilitate risk stratification or new therapeutic
Externí odkaz:
https://doaj.org/article/202db176b8b247c2a0ab69d54362701e
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 2, p e1006693 (2019)
Food allergy is usually difficult to diagnose in early life, and the inability to diagnose patients with atopic diseases at an early age may lead to severe complications. Numerous studies have suggested an association between the infant gut microbiom
Externí odkaz:
https://doaj.org/article/1b29ac9d04dd4f01bb3d770698e083d2
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193797 (2018)
Miniaturized imaging devices have pushed the boundaries of point-of-care imaging, but existing mobile-phone-based imaging systems do not exploit the full potential of smart phones. This work demonstrates the use of simple imaging configurations to de
Externí odkaz:
https://doaj.org/article/d3006aeaa4f8458bbbd8536793d85b46
Autor:
Benjamin A Turturice, Halvor S McGee, Brian Oliver, Melissa Baraket, Brian T Nguyen, Christian Ascoli, Ravi Ranjan, Asha Rani, David L Perkins, Patricia W Finn
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184566 (2017)
BACKGROUND:Differences in asthma severity may be related to inflammation in the airways. The lower airway microbiota has been associated with clinical features such as airway obstruction, symptom control, and response to corticosteroids. OBJECTIVE:To
Externí odkaz:
https://doaj.org/article/79265041dc564ed59c38f1b4134cdab1
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165712 (2016)
BACKGROUND:Obesity is a growing epidemic in most developed countries including the United States resulting in an increased number of obese patients with end-stage renal disease. A previous study has shown that obese patients with end-stage renal dise
Externí odkaz:
https://doaj.org/article/f788266ea5c74874af6490f1b295d53d
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163527 (2016)
BACKGROUND:Metagenome shotgun sequencing presents opportunities to identify organisms that may prevent or promote disease. The analysis of sample diversity is achieved by taxonomic identification of metagenomic reads followed by generating an abundan
Externí odkaz:
https://doaj.org/article/d660e1033b63462ea082615398bb522b
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Among kidney transplant recipients, the treatment of choice for acute T cell mediated rejection (TCMR) with pulse steroids or antibody protocols has variable outcomes. Some rejection episodes are resistant to an initial steroid pulse, but respond to
Externí odkaz:
https://doaj.org/article/e76ce5a95a1e4fe38ed3fadf7f3c62a8
Autor:
Ozcan Altintas, Justin P. Romaire, David L. Perkins, Thomas Sun, Lesheng Wang, Nevil Patel, Nicole M. Callen, Adams B. Burns, Manesh Gopinadhan
Publikováno v:
Macromolecules. 56:2637-2650