Zobrazeno 1 - 10
of 85
pro vyhledávání: '"David L Farrens"'
Autor:
Seksiri Arttamangkul, Andrew Plazek, Emily J Platt, Haihong Jin, Thomas F Murray, William T Birdsong, Kenner C Rice, David L Farrens, John T Williams
Publikováno v:
eLife, Vol 8 (2019)
Identifying neurons that have functional opioid receptors is fundamental for the understanding of the cellular, synaptic and systems actions of opioids. Current techniques are limited to post hoc analyses of fixed tissues. Here we developed a fluores
Externí odkaz:
https://doaj.org/article/afd221fdbb4c475bbda925ce0c8607b0
Publikováno v:
J Biol Chem
Rhodopsin is a canonical class A photosensitive G protein–coupled receptor (GPCR), yet relatively few pharmaceutical agents targeting this visual receptor have been identified, in part due to the unique characteristics of its light-sensitive, coval
Publikováno v:
Biophys J
Biophysical journal, vol 120, iss 20
Biophysical journal, vol 120, iss 20
Styrene-maleic acid (SMA) copolymers solubilize biological membranes to form lipid nanoparticles (SMALPs) that contain membrane proteins surrounded by native lipids, thus enabling the use of a variety of biophysical techniques for structural and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca87aaf5a7b1bab796fb6089a3c00aef
https://europepmc.org/articles/PMC8553795/
https://europepmc.org/articles/PMC8553795/
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Class A G-protein-coupled receptors (GPCRs) normally function as monomers, although evidence from heterologous expression systems suggests that they may sometimes form homodimers and/or heterodimers. This study aims to evaluate possible functional in
Autor:
Jonathan F. Fay, Anthony D. Shumate, Eefei Chen, Stephanie G. Pitch, Weekie Yao, Istvan Szundi, David L. Farrens, David S. Kliger
Publikováno v:
Biophys J
Biophysical journal, vol 120, iss 16
Biophysical journal, vol 120, iss 16
Membrane proteins often require solubilization to study their structure or define the mechanisms underlying their function. In this study, the functional properties of the membrane protein rhodopsin in its native lipid environment were investigated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb6c1661d08c2a5bc5ca6a1d4c4b0dc
https://europepmc.org/articles/PMC8391062/
https://europepmc.org/articles/PMC8391062/
Autor:
Thomas F. Murray, Andrew Plazek, David L. Farrens, Seksiri Arttamangkul, Emily J. Platt, John T. Williams, Haihong Jin, Kenner C. Rice, William T. Birdsong
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Identifying neurons that have functional opioid receptors is fundamental for the understanding of the cellular, synaptic and systems actions of opioids. Current techniques are limited to post hoc analyses of fixed tissues. Here we developed a fluores
Autor:
Haihong Jin, David L. Farrens, John T. Williams, Emily J. Platt, William T. Birdsong, Andrew Plazek, Thomas F. Murray, Seksiri Arttamangkul, Kenner C. Rice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba5c458a8df54043a591f39d682e69ea
https://doi.org/10.7554/elife.49319.028
https://doi.org/10.7554/elife.49319.028
Autor:
Yuji Furutani, Mitsumasa Koyanagi, Yoshihiro Kubo, David L. Farrens, Akihisa Terakita, Hisao Tsukamoto
Publikováno v:
Journal of Biological Chemistry. 290:27176-27187
Melanopsins play a key role in non-visual photoreception in mammals. Their close phylogenetic relationship to the photopigments in invertebrate visual cells suggests they have evolved to acquire molecular characteristics that are more suited for thei
Publikováno v:
BIOPHYSICAL JOURNAL, vol 118, iss 3
Author(s): Pitch, Stephanie G; Szundi, Istvan; Yao, Weekie; Chen, Eefei; Farrens, David L; Kliger, David S
Publikováno v:
Biophysical Journal. 118:94a