Zobrazeno 1 - 10
of 39
pro vyhledávání: '"David L Donermeyer"'
Publikováno v:
eLife, Vol 3 (2014)
Naive T cell precursor frequency determines the magnitude of immunodominance. While a broad T cell repertoire requires diverse positively selecting self-peptides, how a single positively selecting ligand influences naive T cell precursor frequency re
Externí odkaz:
https://doaj.org/article/f8ffb3723fd2403fbaae3306d0c9a9d9
Autor:
Joseph L. Ransdell, Edward Dranoff, Brandon Lau, Wan-Lin Lo, David L. Donermeyer, Paul M. Allen, Jeanne M. Nerbonne
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 532-544 (2017)
Summary: The resurgent component of voltage-gated Na+ (Nav) currents, INaR, has been suggested to provide the depolarizing drive for high-frequency firing and to be generated by voltage-dependent Nav channel block (at depolarized potentials) and unbl
Externí odkaz:
https://doaj.org/article/e856e8bc6d5743638b7f92c3b58afa42
Autor:
Ashley A. Viehmann Milam, Juliet M. Bartleson, Stephen Horvath, David L. Donermeyer, Paul M. Allen, Yu Xia, Takeshi Egawa
Publikováno v:
Nature immunology
T follicular helper (TFH) cells are critical in adaptive immune responses to pathogens and vaccines; however, what drives the initiation of their developmental program remains unclear. Studies suggest that a T cell antigen receptor (TCR)-dependent me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406dec075ca1c5cd68a401bd73db0001
https://doi.org/10.1038/s41590-020-0781-7
https://doi.org/10.1038/s41590-020-0781-7
Autor:
Bernd H. Zinselmeyer, Thaddeus S. Stappenbeck, David L. Donermeyer, Nathan T. Porter, Samantha Hsieh, Gregory W. Strout, Eric C. Martens, Paul M. Allen, Stephen Horvath, Nan Zhang, Brian Saunders
Publikováno v:
The Journal of Immunology. 204:1035-1046
Bacteria express multiple diverse capsular polysaccharides (CPSs) for protection against environmental and host factors, including the host immune system. Using a mouse TCR transgenic CD4+ T cell, BθOM, that is specific for B. thetaiotaomicron and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563482f2c0cd112c0c9207be13b3df4e
https://doi.org/10.4049/jimmunol.1901206
https://doi.org/10.4049/jimmunol.1901206
Publikováno v:
Microbiology
Capsular polysaccharides (CPSs) protect bacteria from host and environmental factors. Many bacteria can express different CPSs and these CPSs are phase variable. For example,Bacteroides thetaiotaomicron (B. theta) is a prominent member of the human g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576cdd95119f6bef8f743a6e74eb372d
http://europepmc.org/articles/PMC8489884
http://europepmc.org/articles/PMC8489884
Autor:
Ashley A Viehmann, Milam, Juliet M, Bartleson, Michael D, Buck, Chih-Hao, Chang, Alexey, Sergushichev, David L, Donermeyer, Wing Y, Lam, Erika L, Pearce, Maxim N, Artyomov, Paul M, Allen
Publikováno v:
Immunohorizons
The contribution of self-peptide-MHC signaling in CD4+ T cells to metabolic programming has not been definitively established. Here, we employed LLO118 and LLO56, two TCRtg CD4+ T cells that recognize the same Listeria epitope. We previously have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::346fe0dacb204bcb1ae0f104aff91889
https://pubmed.ncbi.nlm.nih.gov/32769180
https://pubmed.ncbi.nlm.nih.gov/32769180
Autor:
David L. Donermeyer, Wing Y. Lam, Michael D. Buck, Ashley A. Viehmann Milam, Maxim N. Artyomov, Paul M. Allen, Juliet M. Bartleson, Alexey Sergushichev, Chih-Hao Chang, Erika L. Pearce
Publikováno v:
ImmunoHorizons / The American Association of Immunologists (AAI)
The contribution of self-peptide–MHC signaling in CD4+ T cells to metabolic programming has not been definitively established. In this study, we employed LLO118 and LLO56, two TCRtg CD4+ T cells that recognize the same Listeria epitope. We previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4de2f9b81f114bf7df788c4b5fface
https://hdl.handle.net/21.11116/0000-0007-E40B-C21.11116/0000-0007-E40D-A
https://hdl.handle.net/21.11116/0000-0007-E40B-C21.11116/0000-0007-E40D-A
Autor:
J. Michael White, Stephen Horvath, Bernd H. Zinselmeyer, Haiyang Yu, Ashley A. Viehmann Milam, David L. Donermeyer, Vivek Durai, Kenneth M. Murphy, Saravanan Raju, Paul M. Allen, Juliet M. Bartleson, Veronika Redmann
Publikováno v:
The Journal of Immunology. 200:3429-3437
Intricate processes in the thymus and periphery help curb the development and activation of autoreactive T cells. The subtle signals that govern these processes are an area of great interest, but tuning TCR sensitivity for the purpose of affecting T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b49ee9a9494b6c72813535b4ee601a39
https://doi.org/10.4049/jimmunol.1701422
https://doi.org/10.4049/jimmunol.1701422
Autor:
Samantha, Hsieh, Nathan T, Porter, David L, Donermeyer, Stephen, Horvath, Gregory, Strout, Brian T, Saunders, Nan, Zhang, Bernd, Zinselmeyer, Eric C, Martens, Thaddeus S, Stappenbeck, Paul M, Allen
Publikováno v:
J Immunol
Bacteria express multiple diverse capsular polysaccharides (CPSs) for protection against environmental and host factors, including the host immune system. Using a mouse TCR transgenic CD4+ T cell, BθOM, that is specific for Bacteroides thetaiotaomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fadb4cf16eac894e0d4c4681e114137c
https://pubmed.ncbi.nlm.nih.gov/31900343
https://pubmed.ncbi.nlm.nih.gov/31900343
Autor:
Paul M. Allen, Marta Wegorzewska, Samantha Hsieh, Stephen Horvath, Robert W. P. Glowacki, Eric C. Martens, Christina A. Hickey, David L. Donermeyer, Thaddeus S. Stappenbeck
Publikováno v:
Science Immunology. 4
T cell responses to symbionts in the intestine drive tolerance or inflammation depending on the genetic background of the host. These symbionts in the gut sense the available nutrients and adapt their metabolic programs to use these nutrients efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::643d4255eb1327dd677ff3daf90da787
https://doi.org/10.1126/sciimmunol.aau9079
https://doi.org/10.1126/sciimmunol.aau9079