Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David L DiGiusto"'
Autor:
Dee eLuo, James A Smith, Meadows N A, Anna eSchuh, Katie E Manescu, Kim eBure, Benjamin eDavies, Rob eHorne, Mike eKope, David L DiGiusto, Brindley A David
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
Externí odkaz:
https://doaj.org/article/83f43acf1c18424a9d7feb6758344e2c
Autor:
Dee eLuo, James A Smith, Nick A Meadows, Katie eManescu, Kim eBure, Benjamin eDavies, Rob eHorne, David L DiGiusto, David A Brindley
Publikováno v:
Frontiers in Genetics, Vol 6 (2016)
Rapid innovation in (epi)genetics and biomarker sciences is driving a new drug development and product development pathway, with the personalized medicine era dominated by biologic therapeutics and companion diagnostics. Companion diagnostics (CDx) a
Externí odkaz:
https://doaj.org/article/a4118ff8b7694e259e27471efbe75de9
Autor:
David L DiGiusto, Paula M Cannon, Michael C Holmes, Lijing Li, Anitha Rao, Jianbin Wang, Gary Lee, Philip D. Gregory, Kenneth A Kim, Samuel B Hayward, Kathleen Meyer, Colin Exline, Evan Lopez, Jill Henley, Nancy Gonzalez, Victoria Bedell, Rodica Stan, John A Zaia
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Gene therapy for HIV-1 infection is a promising alternative to lifelong combination antiviral drug treatment. Chemokine receptor 5 (CCR5) is the coreceptor required for R5-tropic HIV-1 infection of human cells. Deletion of CCR5 renders cells resistan
Externí odkaz:
https://doaj.org/article/6baa787e21344953b1fd783b0d550f71
Publikováno v:
Cell and Gene Therapy Insights. 6:325-337
Publikováno v:
Methods in Enzymology ISBN: 9780121820411
Publisher Summary This chapter describes the use of Ca2+-sensitive fluorescent dye technology with the extremely precise technology of flow cytometry for the single-cell analysis of changes in intracellular Ca2+ levels. The model cell involves the an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ee43ce647a70676ba34bf201574d95
https://doi.org/10.1016/0076-6879(87)41055-0
https://doi.org/10.1016/0076-6879(87)41055-0
Autor:
Lindsey M. Skrdlant, Randall J. Armstrong, Brett M. Keidaisch, Mario F. Lorente, David L. DiGiusto
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 8, Iss C, Pp 1-7 (2018)
Lentiviral vectors are a common tool used to introduce new and corrected genes into cell therapy products for treatment of human diseases. Although lentiviral vectors are ideal for delivery and stable integration of genes of interest into the host ce
Externí odkaz:
https://doaj.org/article/0080e272126c4b538ef9c954f90b7251
Publikováno v:
Viruses, Vol 5, Iss 11, Pp 2898-2919 (2013)
Over the past 15 years we have been investigating an alternative approach to treating HIV-1/AIDS, based on the creation of a disease-resistant immune system through transplantation of autologous, gene-modified (HIV-1-resistant) hematopoietic stem and
Externí odkaz:
https://doaj.org/article/c3f0df23ad704f29b8cd7586f6d00069