Zobrazeno 1 - 10
of 61
pro vyhledávání: '"David L Aylor"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Although studies with inbred strains of mice have shown that infarct size is largely determined by the extent of collateral vessel connections between arteries in the brain that enable reperfusion of the ischemic territory, we have identified strain
Externí odkaz:
https://doaj.org/article/80dc20fa8c1c4777843e02e5db59e72b
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 5, Pp 1409-1416 (2016)
Meiotic recombination is a genetic process that is critical for proper chromosome segregation in many organisms. Despite being fundamental for organismal fitness, rates of crossing over vary greatly between taxa. Both genetic and environmental factor
Externí odkaz:
https://doaj.org/article/fa5fa444acb34922ad63d931c730bb6f
Publikováno v:
Am J Hum Genet
Ischemic stroke, caused by vessel blockage, results in cerebral infarction, the death of brain tissue. Previously, quantitative trait locus (QTL) mapping of cerebral infarct volume and collateral vessel number identified a single, strong genetic locu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d72cc72617d917ae67fb2c7036b244
https://europepmc.org/articles/PMC9606478/
https://europepmc.org/articles/PMC9606478/
Autor:
Shannah K. Witchey, Michael G. Doyle, Jacob D. Fredenburg, Genevieve St. Armour, Brian Horman, Melanie T. Odenkirk, David L. Aylor, Erin S. Baker, Heather B. Patisaul
Publikováno v:
Neuroendocrinology.
Introduction: Flame retardants (FRs) are common bodily and environmental pollutants, creating concern about their potential toxicity. We and others have found that the commercial mixture, FireMaster® 550 (FM 550) or its individual brominated (BFR) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164554604087c45a1f9b2eabe474a064
https://doi.org/10.1159/000526959
https://doi.org/10.1159/000526959
Publikováno v:
Genetics
Hybrid male sterility (HMS) contributes to reproductive isolation commonly observed among house mouse (Mus musculus) subspecies, both in the wild and in laboratory crosses. Incompatibilities involving specific Prdm9 alleles and certain Chromosome (Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d8193cd5c3f5bd6fc424d3dd984ef8
https://doi.org/10.1534/genetics.120.303474
https://doi.org/10.1534/genetics.120.303474
Autor:
Lisa E Gralinski, Martin T Ferris, David L Aylor, Alan C Whitmore, Richard Green, Matthew B Frieman, Damon Deming, Vineet D Menachery, Darla R Miller, Ryan J Buus, Timothy A Bell, Gary A Churchill, David W Threadgill, Michael G Katze, Leonard McMillan, William Valdar, Mark T Heise, Fernando Pardo-Manuel de Villena, Ralph S Baric
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005504 (2015)
New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross mouse panel, we demonstrate a gre
Externí odkaz:
https://doaj.org/article/b8f7d6c3b6f74bfd8dd8a1fd634eea07
Autor:
John P Didion, Andrew P Morgan, Amelia M-F Clayshulte, Rachel C Mcmullan, Liran Yadgary, Petko M Petkov, Timothy A Bell, Daniel M Gatti, James J Crowley, Kunjie Hua, David L Aylor, Ling Bai, Mark Calaway, Elissa J Chesler, John E French, Thomas R Geiger, Terry J Gooch, Theodore Garland, Alison H Harrill, Kent Hunter, Leonard McMillan, Matt Holt, Darla R Miller, Deborah A O'Brien, Kenneth Paigen, Wenqi Pan, Lucy B Rowe, Ginger D Shaw, Petr Simecek, Patrick F Sullivan, Karen L Svenson, George M Weinstock, David W Threadgill, Daniel Pomp, Gary A Churchill, Fernando Pardo-Manuel de Villena
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1004850 (2015)
Significant departures from expected Mendelian inheritance ratios (transmission ratio distortion, TRD) are frequently observed in both experimental crosses and natural populations. TRD on mouse Chromosome (Chr) 2 has been reported in multiple experim
Externí odkaz:
https://doaj.org/article/53c2f98bb98349e2a1907e6090291e44
Autor:
Martin T Ferris, David L Aylor, Daniel Bottomly, Alan C Whitmore, Lauri D Aicher, Timothy A Bell, Birgit Bradel-Tretheway, Janine T Bryan, Ryan J Buus, Lisa E Gralinski, Bart L Haagmans, Leonard McMillan, Darla R Miller, Elizabeth Rosenzweig, William Valdar, Jeremy Wang, Gary A Churchill, David W Threadgill, Shannon K McWeeney, Michael G Katze, Fernando Pardo-Manuel de Villena, Ralph S Baric, Mark T Heise
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003196 (2013)
Genetic variation contributes to host responses and outcomes following infection by influenza A virus or other viral infections. Yet narrow windows of disease symptoms and confounding environmental factors have made it difficult to identify polymorph
Externí odkaz:
https://doaj.org/article/7b65541d5dda41df84e78d9a797b012a
Autor:
Andrew Hillhouse, Kranti Konganti, David L. Aylor, Francis Swift-Haire, David W. Threadgill, Thomas Konneker, Drake Phelps, Tiffany A. Garbutt, Alexis Jones
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Mus musculus is the only known species from which embryonic stem cells (ESC) can be isolated under conditions requiring only leukemia inhibitory factor (LIF). Other species are non-permissive in LIF media, and form developmentally primed epiblast ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2671f0f2d8857306ef46d3d976fe4c2b
http://link.springer.com/article/10.1038/s41598-018-32116-8
http://link.springer.com/article/10.1038/s41598-018-32116-8
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 32:283-297
Endocrine disrupting chemicals (EDCs) are compounds that alter the structure and function of the endocrine system and may be contributing to disorders of the reproductive, metabolic, neuroendocrine and other complex systems. Typically, these outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077281bd658550f883b0be837c1d27d9
https://doi.org/10.1016/j.beem.2018.03.011
https://doi.org/10.1016/j.beem.2018.03.011