Zobrazeno 1 - 10
of 135
pro vyhledávání: '"David L, Sigalet"'
Autor:
Sarah W Lai, Elaine de Heuvel, Laurie E Wallace, Bolette Hartmann, Jens J Holst, Mary E Brindle, Prasanth K Chelikani, David L Sigalet
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181453 (2017)
To determine the effects of exogenous glucagon-like peptide-2 (GLP-2), with or without massive distal bowel resection, on adaptation of jejunal mucosa, enteric neurons, gut hormones and tissue reserves in rats.GLP-2 is a gut hormone known to be troph
Externí odkaz:
https://doaj.org/article/0a805c6fe8284822a66a6f8b53efa24a
Autor:
David L Sigalet, Dragan Kravarusic, Decker Butzner, Bolette Hartmann, Jens J Holst, Jon Meddings
Publikováno v:
Canadian Journal of Gastroenterology, Vol 27, Iss 10, Pp 587-592 (2013)
BACKGROUND/OBJECTIVES: The relationship between the enteroendocrine hormone glucagon-like peptide 2 (GLP-2) and intestinal inflammation is unclear. GLP-2 promotes mucosal growth, decreases permeability and reduces inflammation in the intestine; physi
Externí odkaz:
https://doaj.org/article/3cf10f08455d4ad085ba5fa2772d477c
Autor:
Csaba Nyakas, André P van Beek, Edit Somogyi, Gertjan van Dijk, Thomas E. Adrian, David L. Sigalet, Henry S. Koopmans, Christiaan W Hoornenborg
Publikováno v:
Obesity Surgery, 30(7), 2729-2742. SPRINGER
Obesity Surgery
Obesity Surgery
Purpose Ileal transposition (IT) allows exploration of hindgut effects of bariatric procedures in inducing weight loss and reducing adiposity. Here we investigated the role of dietary macronutrient content on IT effects in rats. Methods Male Lewis ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99e1fd16ef86872a8b5e03a55716e01
https://hdl.handle.net/11370/67dda134-3a55-46af-a169-37418c052d62
https://hdl.handle.net/11370/67dda134-3a55-46af-a169-37418c052d62
Autor:
Mohammed Elkhwad, Kiran More, David L. Sigalet, Samira Al-Maraghi, Duane Wong, Myles Crowe, Dhullipala Anand, Santosh K. Yadav, Julianne Metcalf
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Background: Extracorporeal membrane oxygenation (ECMO) is complex life-saving support for acute cardio-respiratory failure, unresponsive to medical treatment. Starting a new ECMO program requires synergizing different aspects of organizational infras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9af4ee68bb8f36a751080d6d73ed0e4
https://www.frontiersin.org/article/10.3389/fped.2020.00506/full
https://www.frontiersin.org/article/10.3389/fped.2020.00506/full
Autor:
Viona Lam, Jens J. Holst, Dana Boctor, Elaine de Heuval, Laurie E. Wallace, Mary Brindle, David L. Sigalet, B. Hartmann
Publikováno v:
Journal of Pediatric Surgery. 53:898-904
This study investigates the relationship between the enteric hormone glucagon-like peptide 2 (GLP-2) production, sensitivity, and intestinal adaptation in infants following resection or repair of gastroschisis.With IRB approval (UCalgary #10656), con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f5cba801be6eb03f7033fc81c5cbc0
https://doi.org/10.1016/j.jpedsurg.2018.02.012
https://doi.org/10.1016/j.jpedsurg.2018.02.012
Autor:
Heather A. Redstone, William D. Buie, David A. Hart, Laurie Wallace, Pamela J. Hornby, Sarah Sague, Jen J. Holst, David L. Sigalet
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
Background. Glucagon-like peptide 2 (GLP-2) is an intestinal specific trophic hormone, with therapeutic potential; the effects on intestinal healing are unknown. We used a rat model of colonic healing, under normoxic, and stress (hypoxic) conditions
Externí odkaz:
https://doaj.org/article/bfba09dc4f3b42cc88bb2dac23b8dc84
Autor:
Noora Al-Shahwani, David L. Sigalet
Publikováno v:
Pediatric Surgery International. 33:405-411
Intestinal failure-associated liver disease (IFALD) remains a serious problem in the treatment of infants with nutritional problems and short bowel syndrome. A review of the recent literature from 2010 to 2016, concentrating on articles related to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edf8f0aca5e5bf580697d02cab98361
https://doi.org/10.1007/s00383-016-4042-7
https://doi.org/10.1007/s00383-016-4042-7
Autor:
Pamela R. Wizzard, Paul W. Wales, Justine M. Turner, Patrick N. Nation, David L. Sigalet, David W. Lim, David L. Bigam, Abdoulaye Diane, Mitsuru Muto, Paul B. Pencharz, Donna F. Vine
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 41:156-170
We aim to study the efficacy of exogenously administered glucagon-like peptide 2 (GLP-2) on intestinal adaptation in 2 preclinical models of neonatal short bowel syndrome (SBS) according to remnant intestinal anatomy, with and without ileum. Furtherm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ef5c3765bc56e8e64d0ad773de3738
https://doi.org/10.1177/0148607116665812
https://doi.org/10.1177/0148607116665812
Publikováno v:
Cureus.
Surgical procedure 'preference lists' are used worldwide, but their practice varies widely. Despite being positioned at a critical point in a surgical care pathway, they are often underemphasized, poorly maintained, and substandard. The following edi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7c6369ea04e9db9fd166f9c3101d7d
https://doi.org/10.7759/cureus.2997
https://doi.org/10.7759/cureus.2997
Autor:
Sonia A. Butterworth, Viona Lam, Linda Casey, Bryan Dicken, Bolette Hartmann, David L. Sigalet, Mary Brindle, Dana Boctor, Vikram Karnik, Jens J. Holst, Elaine de Heuvel
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 41:844-852
Background and aims A glucagon-like peptide 2 (GLP-2) analogue is approved for adults with intestinal failure, but no studies of GLP-2 have included children. This study examined the pharmacokinetics, safety, and nutritional effects of GLP-2 in child
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d92668ad21193de4ebf29294f0b77c
https://doi.org/10.1177/0148607115609566
https://doi.org/10.1177/0148607115609566