Zobrazeno 1 - 10
of 52
pro vyhledávání: '"David L, Kolin"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundPatients with platinum-resistant recurrent high grade serous ovarian carcinoma have poor outcomes and limited treatment options.Case presentationWe present a case of a 48-year-old woman with platinum-resistant high grade serous ovarian carc
Externí odkaz:
https://doaj.org/article/f11e3fa3b6a247dcb107112f535477c8
Autor:
Ala Jo, Allen Green, Jamie E. Medina, Sonia Iyer, Anders W. Ohman, Eric T. McCarthy, Ferenc Reinhardt, Thomas Gerton, Daniel Demehin, Ranjan Mishra, David L. Kolin, Hui Zheng, Jinwoo Cheon, Christopher P. Crum, Robert A. Weinberg, Bo R. Rueda, Cesar M. Castro, Daniela M. Dinulescu, Hakho Lee
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Detecting early cancer through liquid biopsy is challenging due to the lack of specific biomarkers for early lesions and potentially low levels of these markers. The current study systematically develops an extracellular‐vesicle (EV)‐bas
Externí odkaz:
https://doaj.org/article/80311c6a1d4e4c65b0abe22c8b14a2e5
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101237- (2023)
Patients with advanced stage or recurrent mucinous ovarian carcinoma exhibit poor response to standard platinum- and taxane-based chemotherapy and poor prognosis. We report a 29-year-old patient with recurrent ERBB2-amplified mucinous ovarian carcino
Externí odkaz:
https://doaj.org/article/14440632f14748219cf1e8d145c428d8
Autor:
Panagiotis A. Konstantinopoulos, Alexandre André B. A. da Costa, Doga Gulhan, Elizabeth K. Lee, Su-Chun Cheng, Andrea E. Wahner Hendrickson, Bose Kochupurakkal, David L. Kolin, Elise C. Kohn, Joyce F. Liu, Elizabeth H. Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A. Matulonis, Anniina Färkkilä, Alan D. D’Andrea, Geoffrey I. Shapiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
A randomized phase 2 study recently showed that the addition of ATR inhibitor berzosertib to gemcitabine improved PFS compared to gemcitabine alone in patients with ovarian cancer. In this preplanned exploratory study, the authors demonstrate that a
Externí odkaz:
https://doaj.org/article/47ca4fa1fe9849e2a78a9dcd5d68a796
Autor:
Rebecca L. Porter, Siyu Sun, Micayla N. Flores, Emily Berzolla, Eunae You, Ildiko E. Phillips, Neelima KC, Niyati Desai, Eric C. Tai, Annamaria Szabolcs, Evan R. Lang, Amaya Pankaj, Michael J. Raabe, Vishal Thapar, Katherine H. Xu, Linda T. Nieman, Daniel C. Rabe, David L. Kolin, Elizabeth H. Stover, David Pepin, Shannon L. Stott, Vikram Deshpande, Joyce F. Liu, Alexander Solovyov, Ursula A. Matulonis, Benjamin D. Greenbaum, David T. Ting
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Aberrant expression of viral-like repeat elements is a common feature of epithelial cancers, and the substantial diversity of repeat species provides a distinct view of the cancer transcriptome. Repeatome profiling across ovarian, pancreatic, and col
Externí odkaz:
https://doaj.org/article/3ee791906f1046c18bf708762dc93b36
Publikováno v:
Gynecologic Oncology Reports, Vol 40, Iss , Pp 100979- (2022)
We report a 62-year-old patient with uterine carcinosarcoma associated with a germline mutation in the NBN gene which is involved in the homologous recombination repair (HRR) pathway. This patient responded well to several different treatment strateg
Externí odkaz:
https://doaj.org/article/68708be0fb2f409ea17c75d17be87122
Autor:
Danielle C. Costigan, Marisa R. Nucci, Brendan C. Dickson, Martin C. Chang, Sharon Song, Lynette M. Sholl, Jason L. Hornick, Christopher D.M. Fletcher, David L. Kolin
Publikováno v:
The American journal of surgical pathology. 46(10)
NTRK -rearranged uterine sarcomas are rare spindle cell neoplasms that typically arise in the uterine cervix of young women. Some tumors recur or metastasize, but features which predict behavior have not been identified to date. Distinguishing these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1df204d53fcc2ea817cccd48d3e752b
https://pubmed.ncbi.nlm.nih.gov/35713627
https://pubmed.ncbi.nlm.nih.gov/35713627
Autor:
Abbas Agaimy, Blaise A. Clarke, David L. Kolin, Cheng-Han Lee, Jen-Chieh Lee, W. Glenn McCluggage, Patrik Pöschke, Robert Stoehr, David Swanson, Gulisa Turashvili, Matthias W. Beckmann, Arndt Hartmann, Cristina R. Antonescu, Brendan C. Dickson
Publikováno v:
The American journal of surgical pathology. 46(9)
With the widespread application of next-generation sequencing, the genetic landscape of uterine mesenchymal neoplasms has been evolving rapidly to include several recently identified fusion genes. Although chromosomal rearrangements involving the 10q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690a7aa6710d94950373ce8fec82ecc1
https://pubmed.ncbi.nlm.nih.gov/35575789
https://pubmed.ncbi.nlm.nih.gov/35575789
Autor:
Felix KF Kommoss, Basile Tessier‐Cloutier, Leora Witkowski, Erna Forgo, Christian Koelsche, Martin Köbel, William D Foulkes, Cheng‐Han Lee, David L Kolin, Andreas Deimling, Brooke E Howitt
Publikováno v:
The Journal of Pathology. 257:140-145
SWI/SNF (SWItch/Sucrose Non-Fermentable) complex deficiency has been reported in a wide variety of cancers and is often associated with an undifferentiated phenotype. In the gynecologic tract SWI/SNF-deficient cancers are diagnostically challenging a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321243e24012939b8ae835ba15653b62
https://doi.org/10.1002/path.5889
https://doi.org/10.1002/path.5889
Autor:
Anthony N. Karnezis, Asha Nair, Andrew L. Folpe, Bobbie Collett Sutton, Kevin C. Halling, Emily Landers, Marisa R. Nucci, J. Kenneth Schoolmeester, Brendan C. Dickson, David L. Kolin
Publikováno v:
Modern Pathology. 34:1912-1920
Desmoplastic small round cell tumor (DSRCT) is a high-grade round cell sarcoma that typically arises in the abdominopelvic cavity of young males, co-expresses keratins and desmin, and carries a pathognomonic EWSR1-WT1 gene fusion. The EWSR1-WT1 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9481f3d7537c62ec2b7c91d445a7b87b
https://doi.org/10.1038/s41379-021-00843-5
https://doi.org/10.1038/s41379-021-00843-5