Zobrazeno 1 - 10
of 143
pro vyhledávání: '"David L, Becker"'
Publikováno v:
Microorganisms, Vol 12, Iss 2, p 293 (2024)
Cancer therapies developed using bacteria and their components have been around since the 19th century. Compared to traditional cancer treatments, the use of bacteria-derived compounds as cancer therapeutics could offer a higher degree of specificity
Externí odkaz:
https://doaj.org/article/f1cffa480c634e17ae123d10636cb0f9
Autor:
Milton Sheng Yi Kwek, Moogaambikai Thangaveloo, Leigh E. Madden, Anthony R. J. Phillips, David L. Becker
Publikováno v:
Cells, Vol 12, Iss 24, p 2856 (2023)
In the skin, repeated incidents of ischemia followed by reperfusion can result in the breakdown of the skin and the formation of a pressure ulcer. Here we gently applied paired magnets to the backs of mice to cause ischemia for 1.5 h and then removed
Externí odkaz:
https://doaj.org/article/03c0d5daf9e14606992f4b9de567cbde
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Injury to the central nervous system (CNS) provokes an inflammatory reaction and secondary damage that result in further tissue damage and destruction of neurons away from the injury site. Upon injury, expression of connexin 43 (Cx43), a gap junction
Externí odkaz:
https://doaj.org/article/fc29ef57976a4aa6a0a467f38eb5aeeb
Autor:
Debbie X. E. Lim, Toby Richards, Muholan Kanapathy, Thankiah Sudhaharan, Graham D. Wright, Anthony R. J. Phillips, David L. Becker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract High prevalence of non-healing chronic wounds contributes to a huge healthcare burden across the world. Early treatment interventions for non-healing wounds are vital. It was previously shown that accumulation of 15% or more of senescent cel
Externí odkaz:
https://doaj.org/article/0c085bdde7cd4c53b87a024a620457a5
Autor:
Eleni Costa, Babatunde O. Okesola, Christopher Thrasivoulou, David L. Becker, Jan A. Deprest, Anna L. David, Tina T. Chowdhury
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The wound healing capacity of the fetal membranes after spontaneous or iatrogenic membrane rupture is unclear. We examined the healing mechanisms in amniotic membrane (AM) defects after trauma. Traumatised human AM defects were cultured for
Externí odkaz:
https://doaj.org/article/16ee24a902714706801d696a57aa9808
Autor:
Jia Wang Chua, Moogaambikai Thangaveloo, Debbie Xiu En Lim, Leigh E. Madden, Anthony R. J. Phillips, David L. Becker
Publikováno v:
Life, Vol 12, Iss 11, p 1734 (2022)
Objective: Post-surgical peritoneal adhesions are a serious problem for the quality of life and fertility. Yet there are no effective ways of preventing their occurrence. The gap junction protein Cx43 is known to be involved in fibrosis in several di
Externí odkaz:
https://doaj.org/article/b7846b811a2944649cd6a03bcf4f20e1
Publikováno v:
Bioengineering, Vol 9, Iss 7, p 324 (2022)
Scaffolds can promote the healing of burns and chronic skin wounds but to date have suffered from issues with achieving full skin integration. Here, we characterise the wound response by both tissue integration and re-epithelialization to a scaffold
Externí odkaz:
https://doaj.org/article/48dd28a92d704e99a387ecdd59339d7f
Publikováno v:
Health Science Reports, Vol 4, Iss 1, Pp n/a-n/a (2021)
Abstract Background Connexin 43 (Cx43) plays a central role in the inflammatory response and wound healing. Targeting Cx43 expression reduces inflammation in a variety of injuries. The expression pattern of Cx43 has not been described for many inflam
Externí odkaz:
https://doaj.org/article/c9529b09e86f4fc9bb83a067e01d7372
Autor:
David L. Becker, Navin Kumar Verma, Xuezhi Bi, Muhammad Farhan Bin Mohd Fadil, Min Jia Chua, Chris Fang, Moogaambikai Thangaveloo, Zhi Sheng Poh, Tanala Patra Alok, Chin Wai Kiat Toby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c50a14d12b303e5702ae791ae76332
https://doi.org/10.26226/m.6437c125d44f9e0012ceb0c4
https://doi.org/10.26226/m.6437c125d44f9e0012ceb0c4
Publikováno v:
Biology Open, Vol 4, Iss 11, Pp 1473-1480 (2015)
Connexins have been proposed as a target for therapeutic treatment of a variety of conditions. The main approaches have been by antisense or small peptides specific against connexins. Some of these peptides enhance communication while others interfer
Externí odkaz:
https://doaj.org/article/eb1054b524934032b29d2ff5c89ee1fd