Sterol transfer by atypical cholesterol-binding NPC2 proteins in coral-algal symbiosis

Autor: Elizabeth Ann Hambleton, Victor Arnold Shivas Jones, Ira Maegele, David Kvaskoff, Timo Sachsenheimer, Annika Guse

Publikováno v: eLife, Vol 8 (2019)

Reef-building corals depend on intracellular dinoflagellate symbionts that provide nutrients. Besides sugars, the transfer of sterols is essential for corals and other sterol-auxotrophic cnidarians. Sterols are important cell components, and variants

Externí odkaz: https://doaj.org/article/711a02d3b0324e62b1d34c48700f0f75

3-Pyridylnitrene, 2- and 4-pyrimidinylcarbenes, 3-quinolylnitrenes, and 4-quinazolinylcarbenes. Interconversion, ring expansion to diazacycloheptatetraenes, ring opening to nitrile ylides, and ring contraction to cyanopyrroles and cyanoindoles

Autor: Curt Wentrup, Nguyen Mong Lan, Adelheid Lukosch, Pawel Bednarek, David Kvaskoff

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 743-753 (2013)

Precursors of 3-pyridylnitrene and 2- and 4-pyrimidinylcarbenes all afford mixtures of 2- and 3-cyanopyrroles on flash vacuum thermolysis, but 3-cyanopyrroles are the first-formed products. 3-Quinolylnitrenes and 4-quinazolinylcarbenes similarly affo

Externí odkaz: https://doaj.org/article/93a5aff86a7a41acac08676647c21076

Effects of vitamin D supplementation on cognitive and emotional functioning in young adults--a randomised controlled trial.

Autor: Angela J Dean, Mark A Bellgrove, Teresa Hall, Wei Ming Jonathan Phan, Darryl W Eyles, David Kvaskoff, John J McGrath

Publikováno v: PLoS ONE, Vol 6, Iss 11, p e25966 (2011)

BackgroundEpidemiological research links vitamin D status to various brain-related outcomes. However, few trials examine whether supplementation can improve such outcomes and none have examined effects on cognition. This study examined whether Vitami

Externí odkaz: https://doaj.org/article/c5b25e0cb6544d07b88f12a019837ab5

When a 'Dimroth Rearrangement' Is Not a Dimroth Rearrangement

Autor: David Kvaskoff, M. Saeed Mirzaei, Curt Wentrup, Avat Arman Taherpour

Publikováno v: The Journal of organic chemistry. 86(12)

In the Dimroth rearrangement of heterocycles, often pyrimidines, an exocyclic and a ring substituent are interchanged. However, the term Dimroth rearrangement is frequently used even when there is no knowledge of the reaction mechanism and alternativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66346717525357276f959f1538d969f
https://pubmed.ncbi.nlm.nih.gov/34077230

The association between neonatal vitamin D status and risk of schizophrenia

Autor: Bent Nørgaard-Pedersen, Pankaj Sah, Anna A. E. Vinkhuyzen, Thomas H. J. Burne, Esben Agerbo, Victor Anggono, David Kvaskoff, Sandra Meier, Maciej Trzaskowski, Helen Gooch, Arieh Cohen, John J. McGrath, Ole Mors, Men Chee Tan, Manuel Mattheisen, Xiangyang Cui, Se Eun Jang, Darryl W. Eyles, David M. Hougaard, Anders D. Børglum, Preben Bo Mortensen, Naomi R. Wray, Carsten Bøcker Pedersen

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Eyles, D W, Trzaskowski, M, Vinkhuyzen, A A E, Mattheisen, M, Meier, S, Gooch, H, Anggono, V, Cui, X, Tan, M C, Burne, T H J, Jang, S E, Kvaskoff, D, Hougaard, D M, Nørgaard-Pedersen, B, Cohen, A, Agerbo, E, Pedersen, C B, Børglum, A D, Mors, O, Sah, P, Wray, N R, Mortensen, P B & McGrath, J J 2018, ' The association between neonatal vitamin D status and risk of schizophrenia ', Scientific Reports, vol. 8, no. 1, 17692 . https://doi.org/10.1038/s41598-018-35418-z
Scientific Reports

Clues from the epidemiology of schizophrenia, such as the increased risk in those born in winter/spring, have led to the hypothesis that prenatal vitamin D deficiency may increase the risk of later schizophrenia. We wish to explore this hypothesis in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb9c6dcef9d5d1ee2a126ab42bafd23
http://link.springer.com/article/10.1038/s41598-018-35418-z