Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David Kalbermatter"'
Autor:
Stephan Hirschi, Thomas Lemmin, Nooraldeen Ayoub, David Kalbermatter, Daniele Pellegata, Zöhre Ucurum, Jürg Gertsch, Dimitrios Fotiadis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Microbial ion-pumping rhodopsins (MRs) are extensively studied retinal-binding membrane proteins. However, their biogenesis, including oligomerisation and retinal incorporation, remains poorly understood. The bacterial green-light absorbing
Externí odkaz:
https://doaj.org/article/a108a1ee9b9d4375998fcce708237c39
Autor:
Narges Seyfizadeh, David Kalbermatter, Thomas Imhof, Moritz Ries, Christian Müller, Leonie Jenner, Elisabeth Blumenschein, Alexandra Yendrzheyevskiy, Frank Grün, Kevin Moog, Daniel Eckert, Ronja Engel, Philipp Diebolder, Mohamed Chami, Jürgen Krauss, Torsten Schaller, Michaela Arndt
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-22 (2024)
Abstract Background Infections with Herpes simplex virus (HSV)-1 or -2 usually present as mild chronic recurrent disease, however in rare cases can result in life-threatening conditions with a large spectrum of pathology. Monoclonal antibody therapy
Externí odkaz:
https://doaj.org/article/90dc32068a724229a0d3541e5d8a5ec7
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)
The L-lactate-specific transporter SfMCT is a model SLC16 family homologue for the determination of inhibitors and potential drugs. Here, starting from a weakly-binding non-transported ligand, nanomolar affinity inhibitors of SfMCT are developed and
Externí odkaz:
https://doaj.org/article/97e83b41fe4545f685b939f7980553da
Autor:
Hüseyin Ilgü, Jean-Marc Jeckelmann, David Kalbermatter, Zöhre Ucurum, Thomas Lemmin, Dimitrios Fotiadis
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background The L-arginine/agmatine transporter AdiC is part of the arginine-dependent extreme acid resistance system of the bacterium Escherichia coli and its pathogenic varieties such as strain E. coli O157:H7. At the present time, there is
Externí odkaz:
https://doaj.org/article/5a4b8474e2574d198278bd45bb5855ef
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The cryo-EM structure of pentameric green-light absorbing proteorhodopsin together with molecular dynamics simulations and functional studies provides insights into the proton translocation pathway and oligomerization, and a protonation-dependent mec
Externí odkaz:
https://doaj.org/article/be15953b5e8e49b3be8f4c74426e812d
Autor:
Neeta Shrestha, Flavio Max Gall, Cyrille Mathieu, Melanie Michaela Hierweger, Melanie Brügger, Marco P. Alves, Jonathan Vesin, Damiano Banfi, David Kalbermatter, Branka Horvat, Marc Chambon, Gerardo Turcatti, Dimitrios Fotiadis, Rainer Riedl, Philippe Plattet
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance. Each year a huge
Externí odkaz:
https://doaj.org/article/7716b1d33ef34c06b47fd4ee9b13b0ad
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The transport of L-lactate across plasma membranes is catalyzed by proton-driven monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. Here, the authors present the crystal structures of a bacterial SLC16 homologue with the bound su
Externí odkaz:
https://doaj.org/article/b140603bfee541c0b8f279a225e59172
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100024- (2020)
The green-light absorbing proteorhodopsin (GPR) is the prototype of bacterial light-driven proton pumps. It has been the focus of continuous research since its discovery 20 years ago and has sparked the development and application of various biophysi
Externí odkaz:
https://doaj.org/article/e14727547c1940b9b8b38396b4e0fe83
Autor:
David Kalbermatter, Neeta Shrestha, Flavio M. Gall, Marianne Wyss, Rainer Riedl, Philippe Plattet, Dimitrios Fotiadis
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100021- (2020)
Measles virus (MeV) and canine distemper virus (CDV), two members of the Morbillivirus genus, are still causing important global diseases of humans and animals, respectively. To enter target cells, morbilliviruses rely on an envelope-anchored machine
Externí odkaz:
https://doaj.org/article/573cb23fb8ff426cbfe1a9637681e4b8
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100038- (2020)
At the end of 2019, a new highly virulent coronavirus known under the name SARS-CoV-2 emerged as a human pathogen. One key feature of SARS-CoV-2 is the presence of an enigmatic insertion in the spike glycoprotein gene representing a novel multibasic
Externí odkaz:
https://doaj.org/article/33cffc7140784d6295aae0a7c5b46d8b