Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David Kalant"'
Autor:
David Kalant, Steve Phélis, Barbara A. Fielding, Keith N. Frayn, Katherine Cianflone, Allan D. Sniderman
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 12, Pp 1963-1968 (2000)
The objective of this study was to test the hypothesis that increased fatty acid trapping by subcutaneous adipose tissue might contribute to the development and/or maintenance of obesity. To do so, venoarterial (V-A) gradients across subcutaneous adi
Externí odkaz:
https://doaj.org/article/0631abf1a9b14904aaf68ad7a085e8ba
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 9, Pp 1655-1662 (1999)
In comparison to very low density lipoprotein (VLDL), chylomicrons are cleared quickly from plasma. However, small changes in fasting plasma VLDL concentration substantially delay postprandial chylomicron triglyceride clearance. We hypothesized that
Externí odkaz:
https://doaj.org/article/a8f9fa7f8f6f43ee9bb92996d75a73d3
Autor:
Katherine Cianflone, Robin MacLaren, David Kalant, Ratna Samanta, Peter N. Monk, Stéphane A. Laporte, Wei Cui
Publikováno v:
Journal of Biological Chemistry. 280:23936-23944
C5L2 binds acylation-stimulating protein (ASP) with high affinity and is expressed in ASP-responsive cells. Functionality of C5L2 has not yet been demonstrated. Here we show that C5L2 is expressed in human subcutaneous and omental adipose tissue in b
The Chemoattractant Receptor-like Protein C5L2 Binds the C3a des-Arg77/Acylation-stimulating Protein
Autor:
David Kalant, Allan D. Sniderman, Stuart A. Cain, Katherine Cianflone, Peter N. Monk, Magdalena Maslowska
Publikováno v:
Journal of Biological Chemistry. 278:11123-11129
The orphan receptor C5L2 has recently been described as a high affinity binding protein for complement fragments C5a and C3a that, unlike the previously described C5a receptor (CD88), couples only weakly to G(i)-like G proteins (Cain, S. A., and Monk
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 9, Pp 1655-1662 (1999)
In comparison to very low density lipoprotein (VLDL), chylomicrons are cleared quickly from plasma. However, small changes in fasting plasma VLDL concentra- tion substantially delay postprandial chylomicron triglycer- ide clearance. We hypothesized t
Publikováno v:
Molecular immunology. 46(16)
C5L2 is a recently identified receptor for C5a/C5adesArg, C3a and C3adesArg (ASP). C5a/C5adesArg bind with high affinity, with no identified activation. By contrast, some studies demonstrate C3a/ASP binding/activation to C5L2; others do not. Our aim
Autor:
HuiLing Lu, Wei Cui, Mathieu Laplante, Sabina Paglialunga, Katherine Cianflone, Yves Deshaies, David Kalant, Christian Roy
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 293(6)
Acylation-stimulating protein (ASP), a lipogenic hormone, stimulates triglyceride (TG) synthesis and glucose transport upon activation of C5L2, a G protein-coupled receptor. ASP-deficient mice have reduced adipose tissue mass due to increased energy
Autor:
Katherine Cianflone, David Kalant
Publikováno v:
Current opinion in lipidology. 15(3)
Purpose of review The aim of the present review is to summarize recent developments in the area of regulation of fatty acid transport. Recent findings While controversy still exists regarding the contribution of passive diffusion versus protein-media
Publikováno v:
Biochimica et biophysica acta. 1349(2)
HepG2 cells have been widely used to study factors which affect the secretion of apoB100 lipoprotein particles. The objectives of this study were to determine if Lp(a) particles were present in conditioned medium from HepG2 cells and if so, was this
Autor:
David Kalant, Allan D. Sniderman, ZuJun Zhang, Hai Vu, Rita Kohen-Avramoglu, Katherine Cianflone
Publikováno v:
The Journal of biological chemistry. 271(46)
The rate at which HepG2 cells secrete apoB100 lipoproteins is inversely related to the concentration of amino acids in the medium (Zhang, Z., Sniderman, A. D., Kalant, D., Vu, H., Monge, J. C., Tao, Y., and Cianflone, K. (1993) J. Biol. Chem. 268, 26