Zobrazeno 1 - 10
of 21
pro vyhledávání: '"David Kakhniashvili"'
Autor:
Kiran Kumar Reddi, Weiqiang Zhang, Shokoufeh Shahrabi-Farahani, Kenneth Mark Anderson, Mingyue Liu, David Kakhniashvili, Xusheng Wang, Yanhui H. Zhang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2659 (2024)
Many metastatic cancers with poor prognoses correlate to downregulated CD82, but exceptions exist. Understanding the context of this correlation is essential to CD82 as a prognostic biomarker and therapeutic target. Oral squamous cell carcinoma (OSCC
Externí odkaz:
https://doaj.org/article/95b498032a8a4ef387834d9c9c597f2f
Autor:
Kevin A. Hope, Daniel Johnson, P. Winston Miller, Daniel Lopez-Ferrer, David Kakhniashvili, Lawrence T. Reiter
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104879- (2020)
Epilepsy affects millions of individuals worldwide and many cases are pharmacoresistant. Duplication 15q syndrome (Dup15q) is a genetic disorder caused by duplications of the 15q11.2-q13.1 region. Phenotypes include a high rate of pharmacoresistant e
Externí odkaz:
https://doaj.org/article/b145647c77904586b4dfe358d355a680
Autor:
Zunsong, Hu, Luhang, Han, Jiawang, Liu, Jay H, Fowke, Joan C, Han, David, Kakhniashvili, Kaja Z, LeWinn, Nicole R, Bush, W Alex, Mason, Qi, Zhao
Publikováno v:
The American journal of clinical nutrition.
Maternal prepregnancy obesity is an important risk factor for offspring obesity, which may partially operate through prenatal programming mechanisms.The study aimed to systematically identify prenatal metabolomic profiles mediating the intergeneratio
Autor:
Zunsong Hu, Luhang Han, Jiawang Liu, Jay H Fowke, Joan C Han, David Kakhniashvili, Kaja Z LeWinn, Nicole R Bush, W Alex Mason, Qi Zhao
Publikováno v:
The American Journal of Clinical Nutrition. 116:1343-1353
Autor:
Mingqi Li, Ling Li, Sarah Asemota, David Kakhniashvili, Ramesh Narayanan, Xusheng Wang, Francesca-Fang Liao
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Targeting nuclear factor-kappa B (NF-κB) represents a highly viable strategy against chemoresistance in cancers as well as cell death. Ubiquitination, including linear ubiquitination mediated by the linear ubiquitin chain assembly complex (LUBAC), i
Autor:
Kaja Z. LeWinn, Jay H. Fowke, W. Alex Mason, Jiawang Liu, Mehmet Kocak, Nicole R. Bush, Zunsong Hu, Joan C. Han, Frances A. Tylavsky, Qi Zhao, David Kakhniashvili
Publikováno v:
International journal of obesity (2005), vol 45, iss 7
International journal of obesity (2005)
International journal of obesity (2005)
Objective Prenatal metabolomics profiles, providing measures of in utero nutritional and environmental exposures, may improve the prediction of childhood outcomes. We aimed to identify prenatal plasma metabolites associated with early childhood body
Autor:
Qi Zhao, Hui Shen, Jiawang Liu, Chi-Yang Chiu, Kuan-Jui Su, Qing Tian, David Kakhniashvili, Chuan Qiu, Lan-Juan Zhao, Zhe Luo, Hong-Wen Deng
Publikováno v:
Aging. 14(5)
We aimed to validate two metabolites, aspartic acid and glutamic acid, which were associated with sarcopenia-related traits, muscle mass and strength, in our previous untargeted metabolomics study and to identify novel metabolites from five metabolic
Publikováno v:
Molecular & Cellular Proteomics. 18:294-307
Alcohol is one of the most widely misused substances in the world. Alcohol consumption by pregnant women often results in an array of fetal developmental abnormalities, but the damage to the fetus by alcohol remains poorly understood. The limited kno
Publikováno v:
Exp Biol Med (Maywood)
We provide a review of Spectrin isoform function in the cytoplasm, the nucleus, the cell surface, and in intracellular signaling. We then discuss the importance of Spectrin’s E2/E3 chimeric ubiquitin conjugating and ligating activity in maintaining
Publikováno v:
Biophysical Journal. 116:541a-542a