Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David K. Pritchard"'
Publikováno v:
Proceedings of the Institution of Civil Engineers - Bridge Engineering. :1-13
When construction of Kincardine Bridge was completed in 1936, it was the longest road bridge in Scotland and the largest swing-span bridge in Europe. The bridge, listed as category A by Historic Environment Scotland, remains in service 85 years on an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29bde8cca10dd65c1b79cd8e170b7d77
https://doi.org/10.1680/jbren.21.00010
https://doi.org/10.1680/jbren.21.00010
Autor:
Jo N Fleming, Richard A Nash, D O McLeod, David F Fiorentino, Howard M Shulman, M Kari Connolly, Jerry A Molitor, Gretchen Henstorf, Robert Lafyatis, David K Pritchard, Lawrence D Adams, Daniel E Furst, Stephen M Schwartz
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1452 (2008)
Scleroderma is an autoimmune disease with a characteristic vascular pathology. The vasculopathy associated with scleroderma is one of the major contributors to the clinical manifestations of the disease.We used immunohistochemical and mRNA in situ hy
Externí odkaz:
https://doaj.org/article/2e87b1557c3b4ba982bf4c91315e952c
Autor:
Jo N. Fleming, Richard A. Nash, D. O. McLeod, David F. Fiorentino, Howard M. Shulman, M. Kari Connolly, Jerry A. Molitor, Gretchen Henstorf, Robert Lafyatis, David K. Pritchard, Lawrence D. Adams, Daniel E. Furst, Stephen M. Schwartz
Publikováno v:
PLoS ONE, Vol 3, Iss 8 (2008)
Externí odkaz:
https://doaj.org/article/3e96b2719c044cf79edd6c43f584f61f
Autor:
John F. Oram, Lev Becker, Richard P. Beyer, Ellen M. Wijsman, Theo K. Bammler, David K. Pritchard, Tomas Vaisar, Masashi Suzuki, Sina A. Gharib, Jay W. Heinecke
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:2910-2918
Objective— Cholesterol accumulation by macrophages plays a key role in atherogenesis. To begin to develop a global picture of this process, we used proteomics and transcriptomics to analyze foam cells generated with acetyl-low-density lipoprotein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82c549295ad6d5858d25c79dcb4789f
https://doi.org/10.1161/atvbaha.112.300383
https://doi.org/10.1161/atvbaha.112.300383
Autor:
Roger E. Bumgarner, Jay W. Heinecke, Masashi Suzuki, Frederick C. de Beer, Andrew N. Hoofnagle, Kensuke Miyake, Richard P. Beyer, Natsuko Tanimura, David K. Pritchard, Maria C. de Beer, John F. Oram, Lev Becker, Tomas Vaisar, Theo K. Bammler
Publikováno v:
Circulation. 122:1919-1927
Background— High-density lipoprotein (HDL) protects the artery wall by removing cholesterol from lipid-laden macrophages. However, recent evidence suggests that HDL might also inhibit atherogenesis by combating inflammation. Methods and Results—
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9667382880d10d78f9a69a8aadc8a8
https://doi.org/10.1161/circulationaha.110.961193
https://doi.org/10.1161/circulationaha.110.961193
Autor:
Jerry A. Molitor, Heather A. Arnett, Jun Xue, Keith B. Elkon, Jane H. Buckner, David K. Pritchard, Jo Nadine Fleming, Hangjun Duan, Lynn M. Amon, Patricia Breen, Stephen M. Schwartz, Guang Chen
Publikováno v:
Arthritis & Rheumatism. 58:1465-1474
Objective We attempted to elucidate possible pathogenetic mechanisms in scleroderma by analysis of gene expression patterns of purified monocytes and lymphocytes, as well as protein profiles of cytokines and growth factors. Methods Expression analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a14b43ea17f82fb7bde3d224f213ed0
https://doi.org/10.1002/art.23451
https://doi.org/10.1002/art.23451
Autor:
David R. Park, Xi Wang, W. Conrad Liles, Jiangning Li, David K. Pritchard, Roger E. Bumgarner, Stephen M. Schwartz
Publikováno v:
Journal of Leukocyte Biology. 81:328-335
We report the systematic use of large-scale cDNA microarrays to study the gene expression profiles of primary human peripheral blood monocytes (MONO) in comparison with in vitro-differentiated, M-CSF-induced MONO-derived macrophages (MAC) and primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c821afc905d5879826ef9e3a064ade77
https://doi.org/10.1189/jlb.0206124
https://doi.org/10.1189/jlb.0206124
Autor:
David K. Pritchard, Thomas Q. Nhan, Jaeman Byun, Jay W. Heinecke, Subramaniam Pennathur, Alan Chait, Steven M. Schwartz, Junko Takeshita
Publikováno v:
Journal of Biological Chemistry. 281:3096-3104
Somatic mutations induced by oxidative damage of DNA might play important roles in atherogenesis. However, the underlying mechanisms remain poorly understood. Myeloperoxidase, a heme protein expressed by select populations of artery wall macrophages,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b4df4b6db00b0e47015e5b04685c517
https://doi.org/10.1074/jbc.m509236200
https://doi.org/10.1074/jbc.m509236200
Autor:
Jesse C. Wiley, Elizabeth K. Broussard, Juan Pablo Marquez, James Annis, Mary L. Disis, Rachel Kim, David K. Pritchard
The length of time required for preinvasive adenoma to progress to carcinoma, the immunogenicity of colorectal cancer (CRC), and the identification of high-risk populations make development and testing of a prophylactic vaccine for the prevention of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076951f3e6581825ea1925e61a8249f
https://europepmc.org/articles/PMC3718634/
https://europepmc.org/articles/PMC3718634/
Publikováno v:
Circulation Research. 109
Aims: Because arterial diseases are highly specific to different segments and because smooth muscle cells (SMCs) of different branches have distinct embryological origin, we undertook a systematic effort to determine the extent of differences in gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de55dcb1cac98e816cd78af001c400cc
https://doi.org/10.1161/res.109.suppl_1.ap329
https://doi.org/10.1161/res.109.suppl_1.ap329