Zobrazeno 1 - 10
of 85
pro vyhledávání: '"David K. Lavallee"'
Autor:
Robert L. Vessella, Janet A. Mercer-Smith, Jeanette C. Roberts, David K. Lavallee, Mahesh K. Bhalgat
Publikováno v:
Drug Delivery. 4:1-12
The synthetic porphyrins N-benzyl-5,10,15,20-tetrakis(4-carboxyphenyl)porphine (N-bzHTCPP) and N-4-nitrobenzyl-5-(4-carboxyphenyl)-10,15,20-tris(4-sulfophenyl)porphine (NbzHCS3P) represent excellent radiocopper chelating agents that may find utility
Autor:
Mahesh K. Bhalgat, Jeanette C. Roberts, Janet A. Mercer-Smith, Robert L. Vessella, David K. Lavallee
Publikováno v:
Drug Delivery. 4:13-17
Publikováno v:
The Journal of Organic Chemistry. 58:6000-6008
Two new cationic periphery porphyrins, tetrakis(p-(aminomethyl)phenyl)porphyrin, TAMPP, and N-methyltetrakis(p-(aminomethyl)phenyl)porphyrin, N-MTAMPP, have been synthesized. These porphyrins are protonated in a pH range suitable for studies of bindi
Autor:
Yvonne E. Adams, Donald A. Tomalia, David K. Lavallee, Janet A. Mercer-Smith, Jeanette C. Roberts
Publikováno v:
Bioconjugate Chemistry. 1:305-308
Starburst dendrimers, spherical polymers constructed from methyl acrylate and ethylenediamine, were successfully used to covalently couple synthetic porphyrins to antibody molecules. The dendrimers, as linker molecules, have great potential for incre
Autor:
Jeffrey H. Newhouse, Paul J. Bohdiewicz, Rashid A. Fawwaz, Philip O. Alderson, David K. Lavallee, Soji F. Oluwole
Publikováno v:
Investigative Radiology. 25:765-770
Manganese (III) hematoporphyrin (MnHP), a new and stable complex, was prepared, and its toxicity and magnetic resonance (MR) imaging properties were evaluated. In tests of acute and subacute toxicity, no deaths resulted from bolus intravenous injecti
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 17:457-464
The biological characteristics of a radiolabeled metalloporphyrin, 5,10,15,20-tetrakis(4-carboxyphenyl)-porphinato [ 67 Cu]copper (II) ([ 67 Cu]TCPP), in rat lymph nodes, surrounding muscle, fat and blood were determined. Lymphatic tissue localized g
Autor:
Mahesh K. Bhalgat, Brenda D. Knotts, Janet A. Mercer-Smith, Jeanette C. Roberts, Robert L. Vessella, David K. Lavallee
Publikováno v:
Nuclear medicine and biology. 24(2)
The synthetic porphyrins, N -benzyl-5,10,15,20- tetrakis (4-carboxyphenyl)porphine ( N -bzHTCPP) and N -4-nitrobenzyl-5-(4-carboxyphenyl)-10,15,20- tris (4-sulfophenyl)porphine ( N -bzHCS 3 P), represent excellent radiocopper chelating agents that ma
Autor:
Masatoshi Hayashi, Vanda A. Lennon, Cole Dean A, Louis D. Schulte, Patricia L. Mixon, Dawn Lewis, Sherri L. Newmyer, S.A. Schreyer, Daniel J. McCormick, Jeanette C. Roberts, Janet A. Mercer-Smith, Timothy P. Burns, Steve D. Figard, David K. Lavallee
Publikováno v:
New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control ISBN: 9781489906281
We have developed methods to radiolabel large molecules, using porphyrins as bifunctional chelating agents for radiometals. The porphyrins are substituted with an N-benzyl group to activate them for radiometallation under mild reaction conditions. Po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2062a41abb14d185afd8cd53998d069
https://doi.org/10.1007/978-1-4899-0626-7_15
https://doi.org/10.1007/978-1-4899-0626-7_15
Autor:
Theodore S. T. Wang, Soji F. Oluwole, Jeffrey H. Newhouse, Paul J. Bohdiewicz, Philip O. Alderson, Rashid A. Fawwaz, David K. Lavallee
Publikováno v:
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. 17(1)
Autor:
David K. Lavallee
Publikováno v:
Inorganic Chemistry. 15:691-694