Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David K. Krug"'
Autor:
Antonella Favit, Patricia Pinto-Garcia, Emily E. Clements, Alison J. White, Daniel J. Brat, Solomon H. Snyder, Andrew A. Pieper, Jill Conover, Seth Blackshaw, Ajay Verma, David K. Krug
Publikováno v:
Proceedings of the National Academy of Sciences. 97:1845-1850
Poly(ADP-ribose) polymerase (PARP) transfers ADP ribose groups from NAD + to nuclear proteins after activation by DNA strand breaks. PARP overactivation by massive DNA damage causes cell death via NAD + and ATP depletion. Heretofore, PARP has been th
Autor:
Daniel J. Brat, Crystal C. Watkins, Andrew A. Pieper, Zhao-Qi Wang, David K. Krug, Alok Gupta, Seth Blackshaw, Solomon H. Snyder, Ajay Verma
Publikováno v:
Proceedings of the National Academy of Sciences. 96:3059-3064
Streptozotocin (STZ) selectively destroys insulin-producing beta islet cells of the pancreas providing a model of type I diabetes. Poly(ADP-ribose) polymerase (PARP) is a nuclear enzyme whose overactivation by DNA strand breaks depletes its substrate
Publikováno v:
Skeletal radiology. 39(1)
Luxatio erecta humeri is a rare type of inferior glenohumeral dislocation with a unique radiographic appearance; however, the magnetic resonance imaging findings associated with this dislocation have not been described in the radiology literature. Th
Autor:
Kazushi Takahashi, Daniel J. Brat, David K. Krug, Andrew A. Pieper, E O’Hearn, A.I Kaplin, Joel H. Greenberg, Solomon H. Snyder, David D. Ginty, Mark E. Molliver
Publikováno v:
Neuroscience. 102(2)
Type 1 inositol 1,4,5-trisphosphate receptors are phosphorylated by cyclic-AMP-dependent protein kinase A at serines 1589 and 1755, with serine 1755 phosphorylation greatly predominating in the brain. Inositol 1,4,5-trisphosphate receptor protein kin