Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David K Detweiler"'
Autor:
David K. Detweiler, Kaufman Laura
Publikováno v:
Toxicology Methods. 9:285-292
This communication describes an axial electrocardiogram (ECG) lead configuration intended torecord maximal T wave amplitudes of unrestrained, conscious cynomolgus monkeys. The impetus for this work came from the need to develop a cynomolgus monkey mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e257e5814221cc910bb6e556d4c7f4f3
https://doi.org/10.1080/105172399242636
https://doi.org/10.1080/105172399242636
Autor:
David K. Detweiler
Publikováno v:
Specialized Aspects of ECG ISBN: 9780857298799
Comprehensive Electrocardiology
Comprehensive Electrocardiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517026294d3b010b33faeb4db0ae0ea1
https://doi.org/10.1007/978-0-85729-880-5_9
https://doi.org/10.1007/978-0-85729-880-5_9
Publikováno v:
Journal of the American Veterinary Medical Association. 231:1033-1034
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dbefba77acbc913153c4825b6185c37
https://doi.org/10.2460/javma.231.7.1033
https://doi.org/10.2460/javma.231.7.1033
Autor:
David K. Detweiler, Robert H. Cox
Publikováno v:
Mechanisms of Ageing and Development. 44:51-67
Arteries were obtained from several sites in young (YGH) and old racing greyhounds (OGH). Segments were used for the determination of arterial wall mechanics under conditions of active (norepinephrine) and passive (Ca2+ free and 2 mM EGTA) smooth mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafebe49b6cee0b53c94615b32c30aff
https://doi.org/10.1016/0047-6374(88)90079-6
https://doi.org/10.1016/0047-6374(88)90079-6
Autor:
David K. Detweiler
Publikováno v:
Toxicologic Pathology. 17:94-108
The spontaneous arterial diseases of the dog relevant to safety assessment studies of drugs are the extramural coronary arteritis of Hartman, intramural coronary arteriosclerosis (with amyloid deposition) occurring in older dogs with cardiac disabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da29be525260daa936b0bb2a9ee284c0
https://doi.org/10.1177/019262338901700105
https://doi.org/10.1177/019262338901700105
Publikováno v:
Toxicological Sciences. 5:391-398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8081301460d380d3ed2f090235d6487b
https://doi.org/10.1093/toxsci/5.2.391
https://doi.org/10.1093/toxsci/5.2.391
Publikováno v:
Fundamental and Applied Toxicology. 5:391-398
Repeated direct puncture of the central ear (intermediate auricular) artery to obtain mean arterial blood pressure in control and hypertensive dogs was evaluated. Unilateral nephrectomy and partial constriction of the contralateral renal artery were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3204a725240f026eeb58b2723e7f066
https://doi.org/10.1016/0272-0590(85)90087-9
https://doi.org/10.1016/0272-0590(85)90087-9
Autor:
David K. Detweiler, P. J. DeBaecke, John L. Robertson, C. S. Streett, P. S. Struve, S. A. Kutz, R. E. Cimprich
Publikováno v:
Toxicologic Pathology. 9:19-21
Three apparently healthy beagle dogs (6-8 months old) from a commercial supplier were found to have electrocardiographic abnormalities on routine screening. At postmortem, areas of ventricular myocardial thinning and/or fine gray streaks were present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af073f73481f4c02452c3464f6f697f8
https://doi.org/10.1177/019262338100900202
https://doi.org/10.1177/019262338100900202
Autor:
David K. Detweiler
Publikováno v:
Myocardial Injury ISBN: 9781468444742
After a long period when reviews of cardiovascular toxicology were sporadic (Bohle, 1966; Wenzel, 1967; Selye, 1970: Chung and Dean, 1972; Davies and Gold, 1977) the literature has been dramatically enriched during the past 18 months by the appearanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb211497f3206770436bc4b4b6949d5a
https://doi.org/10.1007/978-1-4684-4472-8_35
https://doi.org/10.1007/978-1-4684-4472-8_35
Autor:
David K. Detweiler, George E. Fillmore
Publikováno v:
Toxicology and applied pharmacology. 25(3)
Subacute, nonfatal digoxin toxicosis was maintained in 10 beagles for a period of 17–20 days employing an iv loading dose of 0.125–0.150 mg/kg and daily iv maintenance doses of 0.015 mg/kg. Six of the dogs were also given, concurrent with the dig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60415600cfa65327d8476b387fc5ce0f
https://pubmed.ncbi.nlm.nih.gov/4728071
https://pubmed.ncbi.nlm.nih.gov/4728071