Zobrazeno 1 - 10
of 38
pro vyhledávání: '"David K Clarke"'
Autor:
Marnie L Elizaga, Shuying S Li, Nidhi K Kochar, Gregory J Wilson, Mary A Allen, Hong Van N Tieu, Ian Frank, Magdalena E Sobieszczyk, Kristen W Cohen, Brittany Sanchez, Theresa E Latham, David K Clarke, Michael A Egan, John H Eldridge, Drew Hannaman, Rong Xu, Ayuko Ota-Setlik, M Juliana McElrath, Christine Mhorag Hay, NIAID HIV Vaccine Trials Network (HVTN) 087 Study Team
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202753 (2018)
BACKGROUND:The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations. The objective of this study was to test the safe
Externí odkaz:
https://doaj.org/article/799ab45103694bff91a425fb6ec10484
Autor:
Lukkana Suksanpaisan, Rong Xu, Mulu Z. Tesfay, Carolyn Bomidi, Stefan Hamm, Rianna Vandergaast, Nathan Jenks, Michael B. Steele, Ayuko Ota-Setlik, Hinna Akhtar, Amara Luckay, Rebecca Nowak, Kah Whye Peng, John H. Eldridge, David K. Clarke, Stephen J. Russell, Rosa Maria Diaz
Publikováno v:
Molecular Therapy: Oncolytics, Vol 10, Iss , Pp 1-13 (2018)
Immunotherapy for HPVPOS malignancies is attractive because well-defined, viral, non-self tumor antigens exist as targets. Several approaches to vaccinate therapeutically against HPV E6 and E7 antigens have been adopted, including viral platforms suc
Externí odkaz:
https://doaj.org/article/3396dace4a2548be8e2c17cb86f01e32
Autor:
Lisa Marie Mac, Sonali Kochhar, Bettina Klug, Baevin Carbery, Vidisha Singh, Stephen J. Seligman, R. Michael Hendry, John K. Rose, David K. Clarke, Robert T. Chen
Publikováno v:
Vaccine
The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) was formed to evaluate the safety of live, recombinant viral vaccines incorporating genes from heterologous viral and other microbial pathogens in their genome (so-called "
Autor:
Thomas P. Monath, Vidisha Singh, Jayanthi J. Wolf, Brian K. Martin, Jakub K. Simon, David K. Clarke, Kayvon Modjarrad, Richard D. Nichols, D. Gray Heppner, Beth-Ann Coller, Sean P. Troth, Sheri Dubey, James S. Robertson, Joan Fusco, Patricia E. Fast
Publikováno v:
Vaccine: X, Vol 1, Iss, Pp-(2019)
Vaccine: X
Vaccine: X
The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG) was formed to evaluate the safety and characteristics of live, recombinant viral vector vaccines. A recent publication by the V3SWG described live, attenuated, recombinant
Autor:
David K. Clarke, Theresa E. Latham, Michael A. Egan, Amara Luckay, Lucy A. Ward, Ayuko Ota-Setlik, Terry J. Higgins, Tracy Chen, Rong Xu, Janice M. Rusnak, Marc Tremblay, Susan E. Witko, Demetrius Matassov, Susan Sciotto-Brown, Luz Hermida, Cheryl S. Gerardi, John H. Eldridge
Publikováno v:
The Lancet. Infectious diseases. 20(4)
Summary Background The safety and immunogenicity of a highly attenuated recombinant vesicular stomatitis virus (rVSV) expressing HIV-1 gag (rVSVN4CT1-HIV-1gag1) was shown in previous phase 1 clinical studies. An rVSV vector expressing Ebola virus gly
Autor:
Rong Xu, Kristen W. Cohen, John H. Eldridge, Nidhi Kochar, Georgia D. Tomaras, Ian Frank, Michael A. Egan, M. Juliana McElrath, Drew Hannaman, Daryl E. Morris, Christine M. Hay, Ayuko Ota-Setlik, Raphael Gottardo, Nicole Frahm, Magdalena E. Sobieszczyk, Shuying S. Li, Mary Allen, Lawrence Corey, David K. Clarke, Stephen C. De Rosa, Hong Van Tieu, Gregory J. Wilson, Greg Finak, Peter B. Gilbert, Marnie Elizaga
Publikováno v:
Clinical and Vaccine Immunology. 24
The HIV Vaccine Trials Network (HVTN) 087 vaccine trial assessed the effect of increasing doses of pIL-12 (interleukin-12 delivered as plasmid DNA) adjuvant on the immunogenicity of an HIV-1 multiantigen (MAG) DNA vaccine delivered by electroporation
Autor:
Rong Xu, Karla A. Fenton, Ayuko Ota-Setlik, Krystle N. Agans, John H. Eldridge, Chad E. Mire, Demetrius Matassov, Theresa E. Latham, David K. Clarke, Michael A. Egan, Thomas W. Geisbert, Joan B. Geisbert
Publikováno v:
Nature
The family Filoviridae contains three genera, Ebolavirus (EBOV), Marburg virus, and Cuevavirus1. Some members of the EBOV genus, including Zaire ebolavirus (ZEBOV), can cause lethal hemorrhagic fever in humans. During 2014 an unprecedented ZEBOV outb
Autor:
Shuying S, Li, Nidhi K, Kochar, Marnie, Elizaga, Christine M, Hay, Gregory J, Wilson, Kristen W, Cohen, Stephen C, De Rosa, Rong, Xu, Ayuko, Ota-Setlik, Daryl, Morris, Greg, Finak, Mary, Allen, Hong-Van, Tieu, Ian, Frank, Magdalena E, Sobieszczyk, Drew, Hannaman, Raphael, Gottardo, Peter B, Gilbert, Georgia D, Tomaras, Lawrence, Corey, David K, Clarke, Michael A, Egan, John H, Eldridge, M Juliana, McElrath, Nicole, Frahm
Publikováno v:
Clinical and vaccine immunology : CVI. 24(11)
The HIV Vaccine Trials Network (HVTN) 087 vaccine trial assessed the effect of increasing doses of pIL-12 (interleukin-12 delivered as plasmid DNA) adjuvant on the immunogenicity of an HIV-1 multiantigen (MAG) DNA vaccine delivered by electroporation
Autor:
Krystle N. Agans, Michael A. Egan, Theresa E. Latham, Ayuko Ota-Setlik, Amanda Burnaugh, Thomas L. Rudge, Chad E. Mire, Carol L. K. Sabourin, Morgan Q. S. Wendling, Rong Xu, David K. Clarke, Joan B. Geisbert, John H. Eldridge, Dean J. Kobs, Thomas W. Geisbert, Demetrius Matassov
Publikováno v:
Journal of virology. 92(3)
Previous studies demonstrated that a single intramuscular (i.m.) dose of an attenuated recombinant vesicular stomatitis virus (rVSV) vector (VesiculoVax vector platform; rVSV-N4CT1) expressing the glycoprotein (GP) from the Mayinga strain of Zaire eb
Autor:
Stefan Hamm, Theresa E. Latham, David K. Clarke, John H. Eldridge, Scott C. Weaver, Robert L. Seymour, Grace Leal, Demetrius Matassov, Rebecca M. Nowak, Farooq Nasar, Robert B. Tesh, Rodion Gorchakov
Publikováno v:
Journal of Virology
The demonstrated clinical efficacy of a recombinant vesicular stomatitis virus (rVSV) vaccine vector has stimulated the investigation of additional serologically distinct Vesiculovirus vectors as therapeutic and/or prophylactic vaccine vectors to com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4702a44ace3cbaf06fed9f02a06739ba
https://europepmc.org/articles/PMC5375677/
https://europepmc.org/articles/PMC5375677/