Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David Jonathan Wasilko"'
Autor:
David Jonathan Wasilko, Brian S. Gerstenberger, Kathleen A. Farley, Wei Li, Jennifer Alley, Mark E. Schnute, Ray J. Unwalla, Jorge Victorino, Kimberly K. Crouse, Ru Ding, Parag V. Sahasrabudhe, Fabien Vincent, Richard K. Frisbie, Alpay Dermenci, Andrew Flick, Chulho Choi, Gary Chinigo, James J. Mousseau, John I. Trujillo, Philippe Nuhant, Prolay Mondal, Vincent Lombardo, Daniel Lamb, Barbara J. Hogan, Gurdeep Singh Minhas, Elena Segala, Christine Oswald, Ian W. Windsor, Seungil Han, Mathieu Rappas, Robert M. Cooke, Matthew F. Calabrese, Gabriel Berstein, Atli Thorarensen, Huixian Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The CC chemokine receptor 6 (CCR6) is a potential target for chronic inflammatory diseases. Previously, we reported an active CCR6 structure in complex with its cognate chemokine CCL20, revealing the molecular basis of CCR6 activation. Here,
Externí odkaz:
https://doaj.org/article/91af6bd491994266b492f68b0994ea6e
Autor:
David Jonathan Wasilko, Zachary Lee Johnson, Mark Ammirati, Ye Che, Matthew C. Griffor, Seungil Han, Huixian Wu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Chemokine receptors are GPCRs involved in immune responses and regulated by small protein ligands known as chemokines. A structural study of the human CCR6/CCL20–Go complex reveals that CCL20 binds in a shallow extracellular pocket, and suggests th
Externí odkaz:
https://doaj.org/article/563862bc1d384d9c84f3cca32e285ede
Autor:
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S. Chang, Stephen Noell, Timothy L. Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A. Piotrowski, Kathleen A. Farley, Tamara Gilbert, Lisa M. Aschenbrenner, Kimberly F. Fennell, Jason K. Dutra, Mary Xu, Chunyang Guo, Alison E. Varghese, Justin Bellenger, Alandra Quinn, Christopher W. am Ende, Graham M. West, Matthew C. Griffor, Donald Bennett, Matthew Calabrese, Claire M. Steppan, Seungil Han, Huixian Wu
Publikováno v:
Nature Structural & Molecular Biology. 30:22-30
Glycerol-3-phosphate acyltransferase (GPAT)1 is a mitochondrial outer membrane protein that catalyzes the first step of de novo glycerolipid biosynthesis. Hepatic expression of GPAT1 is linked to liver fat accumulation and the severity of nonalcoholi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40abbd054f7e4f0b7d37c1f6aa452bc0
https://doi.org/10.1038/s41594-022-00884-7
https://doi.org/10.1038/s41594-022-00884-7