Zobrazeno 1 - 10
of 60
pro vyhledávání: '"David Jarrossay"'
Autor:
Adrian Ciurea, Burkhard Möller, Andrea Rinaldi, Veronica Martini, Ylenia Silvestri, Gabriela Danelon, Flavio Flamigni, David Jarrossay, Ivo Kwee, Mathilde Foglierini, Valentina Cecchinato, Mariagrazia Uguccioni
Publikováno v:
RMD Open, Vol 10, Iss 1 (2024)
Objectives Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease affecting mainly the axial skeleton. Peripheral involvement (arthritis, enthesitis and dactylitis) and extra-musculoskeletal manifestations, including uveitis, psorias
Externí odkaz:
https://doaj.org/article/7193f0f75d5e4be691e4425eaf556f7b
Autor:
Serena Melgrati, Egle Radice, Rafet Ameti, Elin Hub, Sylvia Thelen, Pawel Pelczar, David Jarrossay, Antal Rot, Marcus Thelen
Publikováno v:
PLoS Biology, Vol 21, Iss 5, p e3002111 (2023)
Atypical chemokine receptors (ACKRs) scavenge chemokines and can contribute to gradient formation by binding, internalizing, and delivering chemokines for lysosomal degradation. ACKRs do not couple to G-proteins and fail to induce typical signaling i
Externí odkaz:
https://doaj.org/article/db3daf668bb049ca8e1f22c49ababbe0
Autor:
Egle Radice, Rafet Ameti, Serena Melgrati, Mathilde Foglierini, Paola Antonello, Rolf A.K. Stahl, Sylvia Thelen, David Jarrossay, Marcus Thelen
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107951- (2020)
Summary: The marginal zone (MZ) contributes to the highly organized spleen microarchitecture. We show that expression of atypical chemokine receptor 3 (ACKR3) defines two equal-sized populations of mouse MZ B cells (MZBs). ACKR3 is required for devel
Externí odkaz:
https://doaj.org/article/47796642acac49dea27c5c2ec17fc371
Autor:
Alberto Toso, Ajinkya Revandkar, Diletta Di Mitri, Ilaria Guccini, Michele Proietti, Manuela Sarti, Sandra Pinton, Jiangwen Zhang, Madhuri Kalathur, Gianluca Civenni, David Jarrossay, Erica Montani, Camilla Marini, Ramon Garcia-Escudero, Eugenio Scanziani, Fabio Grassi, Pier Paolo Pandolfi, Carlo V. Catapano, Andrea Alimonti
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 75-89 (2014)
Summary: Prosenescence therapy has recently emerged as a novel therapeutic approach for treating cancer. However, this concept is challenged by conflicting evidence showing that the senescence-associated secretory phenotype (SASP) of senescent tumor
Externí odkaz:
https://doaj.org/article/c94fd7136b0645978c258289d1966502
Autor:
Federico Mele, Chiara Fornara, David Jarrossay, Milena Furione, Alessia Arossa, Arsenio Spinillo, Antonio Lanzavecchia, Giuseppe Gerna, Federica Sallusto, Daniele Lilleri
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187731 (2017)
Congenital human cytomegalovirus (HCMV) infection is the major cause of birth defects and a precise definition of the HCMV-specific T-cell response in primary infection may help define reliable correlates of immune protection during pregnancy. In thi
Externí odkaz:
https://doaj.org/article/a8fd2ffe76214264bd6ccd4f5a38e5af
Autor:
Stian André Engen, Håkon Valen Rukke, Simone Becattini, David Jarrossay, Inger Johanne Blix, Fernanda Cristina Petersen, Federica Sallusto, Karl Schenck
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104306 (2014)
BACKGROUND: Carriage of and infection with Streptococcus pneumoniae is known to predominantly induce T helper 17 (Th17) responses in humans, but the types of Th cells showing reactivity towards commensal streptococci with low pathogenic potential, su
Externí odkaz:
https://doaj.org/article/86899e2cb6e1441aac46a7ec8c226b8a
Autor:
Davide Corti, Johannes P M Langedijk, Andreas Hinz, Michael S Seaman, Fabrizia Vanzetta, Blanca M Fernandez-Rodriguez, Chiara Silacci, Debora Pinna, David Jarrossay, Sunita Balla-Jhagjhoorsingh, Betty Willems, Maria J Zekveld, Hanna Dreja, Eithne O'Sullivan, Corinna Pade, Chloe Orkin, Simon A Jeffs, David C Montefiori, David Davis, Winfried Weissenhorn, Aine McKnight, Jonathan L Heeney, Federica Sallusto, Quentin J Sattentau, Robin A Weiss, Antonio Lanzavecchia
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8805 (2010)
The isolation of human monoclonal antibodies (mAbs) that neutralize a broad spectrum of primary HIV-1 isolates and the characterization of the human neutralizing antibody B cell response to HIV-1 infection are important goals that are central to the
Externí odkaz:
https://doaj.org/article/1e6dbd71d67b44808b1c11781a2ed731
Autor:
Jun Siong Low, Josipa Jerak, M. Alejandra Tortorici, Matthew McCallum, Dora Pinto, Antonino Cassotta, Mathilde Foglierini, Federico Mele, Rana Abdelnabi, Birgit Weynand, Julia Noack, Martin Montiel-Ruiz, Siro Bianchi, Fabio Benigni, Nicole Sprugasci, Anshu Joshi, John E. Bowen, Cameron Stewart, Megi Rexhepaj, Alexandra C. Walls, David Jarrossay, Diego Morone, Philipp Paparoditis, Christian Garzoni, Paolo Ferrari, Alessandro Ceschi, Johan Neyts, Lisa A. Purcell, Gyorgy Snell, Davide Corti, Antonio Lanzavecchia, David Veesler, Federica Sallusto
Publikováno v:
Science. 377:735-742
The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal antibodies (mAbs) that bind to all human-infecting coronavirus spike proteins from severe acute re
Autor:
Filippo Bianchini, Virginia Crivelli, Morgan E. Abernathy, Concetta Guerra, Martin Palus, Jonathan Muri, Harold Marcotte, Antonio Piralla, Mattia Pedotti, Raoul De Gasparo, Luca Simonelli, Milos Matkovic, Chiara Toscano, Maira Biggiogero, Veronica Calvaruso, Pavel Svoboda, Tomás Cervantes Rincón, Tommaso Fava, Lucie Podešvová, Akanksha A. Shanbhag, Andrea Celoria, Jacopo Sgrignani, Michal Stefanik, Vaclav Hönig, Veronika Pranclova, Tereza Michalcikova, Jan Prochazka, Giuditta Guerrini, Dora Mehn, Annalisa Ciabattini, Hassan Abolhassani, David Jarrossay, Mariagrazia Uguccioni, Donata Medaglini, Qiang Pan-Hammarström, Luigi Calzolai, Daniel Fernandez, Fausto Baldanti, Alessandra Franzetti-Pellanda, Christian Garzoni, Radislav Sedlacek, Daniel Ruzek, Luca Varani, Andrea Cavalli, Christopher O. Barnes, Davide F. Robbiani
Publikováno v:
Science Immunology
Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants diminishes the efficacy of vaccines and antiviral monoclonal antibodies. Continued development of immunotherapies and vaccine immunogens resilient to viral evolution i
Autor:
Jonathan Muri, Valentina Cecchinato, Andrea Cavalli, Akanksha A. Shanbhag, Milos Matkovic, Maira Biggiogero, Pier Andrea Maida, Jacques Moritz, Chiara Toscano, Elaheh Ghovehoud, Raffaello Furlan, Franca Barbic, Antonio Voza, Guendalina De Nadai, Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Lilly A. Murray, Gabriela Danelon-Sargenti, Simone Moro, Tao Gong, Pietro Piffaretti, Filippo Bianchini, Virginia Crivelli, Lucie Podešvová, Mattia Pedotti, David Jarrossay, Jacopo Sgrignani, Sylvia Thelen, Mario Uhr, Enos Bernasconi, Andri Rauch, Antonio Manzo, Adrian Ciurea, Marco B. L. Rocchi, Luca Varani, Bernhard Moser, Barbara Bottazzi, Marcus Thelen, Brian A. Fallon, Onur Boyman, Alberto Mantovani, Christian Garzoni, Alessandra Franzetti-Pellanda, Mariagrazia Uguccioni, Davide F. Robbiani
Publikováno v:
Muri, Jonathan; Cecchinato, Valentina; Cavalli, Andrea; Shanbhag, Akanksha A; Matkovic, Milos; Biggiogero, Maira; Maida, Pier Andrea; Moritz, Jacques; Toscano, Chiara; Ghovehoud, Elaheh; Furlan, Raffaello; Barbic, Franca; Voza, Antonio; De Nadai, Guendalina; Cervia, Carlo; Zurbuchen, Yves; Taeschler, Patrick; Murray, Lilly A; Danelon-Sargenti, Gabriela; Moro, Simone; ... (2023). Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course. Nature immunology, 24(4), pp. 604-611. Nature Publishing Group 10.1038/s41590-023-01445-w
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other immune factors are associated with adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0f8dec0174a4b1d7107ac5687cdb9f