The effect of vaccination on transmission of SARS-CoV-2 (COVID-19): a rapid review

Autor: Jessica Williams, Sasha Barratte, Tom Winfield, Lauren Elston, Katie McDermott, David Jarrom, Elise Hasler, Caron Potter, Ruth Lewis, Alison Cooper, Adrian Edwards

This is an update (literature search up to 15 March 2022) of arapid reviewexamining whether vaccination against SARS-CoV-2 (COVID-19) affects transmission of SARS-CoV-2.Streamlined systematic methodologies were used to accelerate the review process.T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf6beceac97354f197f8fdbcb480bc49
https://doi.org/10.1101/2022.12.09.22283255

The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN

Autor: Antonio E Graziano, Martin A Day, Peter F. Searle, Andrew J. Christofferson, J. L. Ross Anderson, David Jarrom, Eva I. Hyde, Scott A. White

Publikováno v: 'Biochemical Journal ', vol: 478, pages: 2601-2617 (2021)
Day, M A, Jarrom, D, Christofferson, A J, Graziano, A E, Anderson, J L R, Searle, P F, Hyde, E I & White, S A 2021, ' The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN ', Biochemical Journal, vol. 478, no. 13, pp. 2601-2617 . https://doi.org/10.1042/BCJ20210160

NfsA is a dimeric flavoprotein that catalyses the reduction in nitroaromatics and quinones by NADPH. This reduction is required for the activity of nitrofuran antibiotics. The crystal structure of free Escherichia coli NfsA and several homologues hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eca0ec6624e12458c36a47eb25f8a54
https://doi.org/10.1042/bcj20210160

PP91 Developing A Re-assessment Process For Non-medicine Health Technologies In Wales

Autor: Jessica Williams, David Jarrom

Publikováno v: International Journal of Technology Assessment in Health Care. 38:S69-S70

IntroductionUpdating of health technology assessments (HTAs) is generally more efficient than starting again when new evidence emerges, but there is no clear guidance on how to do this. Health Technology Wales (HTW) has developed a re-assessment proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b510726421f3c705ec610530c134fc99
https://doi.org/10.1017/s0266462322002185

PP57 Collaborating In Times Of COVID: The Launch Of The National Wales COVID-19 Evidence Centre

Autor: Lauren Elston, Thomas Winfield, Jenni Washington, David Jarrom, Susan Myles, Ruth Lewis, Alison Cooper, Micaela Gal, Adrian Edwards

Publikováno v: International Journal of Technology Assessment in Health Care. 38:S59-S59

IntroductionThe COVID-19 pandemic has had a dramatic impact on the health and social care landscape, both in terms of service provision and citizen need. Responsive, evidence-based research is essential to develop and implement appropriate policies a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe6d8eea558876a591daef32956c5890
https://doi.org/10.1017/s0266462322001945

How to best test suspected cases of COVID-19: an analysis of the diagnostic performance of RT-PCR and alternative molecular methods for the detection of SARS-CoV-2

Autor: Hrvoje Vrazic, Gottfried Endel, Susan Myles, Matthew Prettyjohns, David Jarrom, Adrian Mironas, Evan Campbell, Sabine Ettinger, Jennifer Washington, Ingrid Wilbacher

As COVID-19 testing is rolled out increasingly widely, the use of a range of alternative testing methods will be beneficial in ensuring testing systems are resilient and adaptable to different clinical and public health scenarios. Here, we compare an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73b57e05688a0b8a65d24cf0180129e3
https://doi.org/10.1101/2021.01.15.21249863