Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David J. Zelinger"'
Publikováno v:
American Heart Journal, 135(4), 98-106. Mosby Inc.
Cost-effectiveness analyses are routinely performed to determine whether the additional cost of a novel therapy is balanced by additional effectiveness. The definitions of costs and effects involve a variety of assumptions, both in general economic t
Publikováno v:
Regulatory Toxicology and Pharmacology. 18:206-213
A retrospective evaluation of previously conducted acute tolerance tests in rats and mice, following oral and intravenous routes of administration, and a review of the literature indicated that a minimum of three animals per group was adequate to cha
Publikováno v:
Toxicological Sciences. 20:147-154
Ipazilide fumarate (WIN 54177-4) is a chemically novel antiarrhythmic agent that prolongs ventricular refractoriness and possesses antiectopic activity. The compound is being developed as oral and iv therapy for ventricular and supraventricular arrhy
Autor:
Arnold E. Postlethwaite, Michael H. Weisman, Maureen D. Mayes, James N. Woody, William J. Koopman, David J. Zelinger, Larry W. Moreland, Robert W. Lightfoot, Thomas J. Schnitzer, Leonard Calabrese, Parks W. Pratt
Publikováno v:
Arthritis and rheumatism. 38(11)
Objective. To evaluate the clinical response to and safety of single and repeat doses of a chimeric anti-CD4 monoclonal antibody, cM-T412, in patients with rheumatoid arthritis (RA) concomitantly treated with a stable regimen of low-dose methotrexate
Autor:
David J. Zelinger, Robert H. Diamond, Steven T. Pals, Michael O. Montgomery, Marit M. van Santen
Publikováno v:
Gastroenterology. 140:S-737
Publikováno v:
Toxicologic pathology. 21(1)
Recombinant human interleukin 4 (rhuIL-4) is a candidate for the treatment of refractory cancer based on its potential to enhance immune function. Recombinant human IL-4 was administered subcutaneously at 0, 1, 5, or 25 μg/kg/day for 28 days with a
Autor:
Robert L. Dixon, Thomas A. Barbolt, David J. Zelinger, Yigal Greener, David P. Benziger, Jon P. Kimball, Brian A. Mayes, Alan M. Ezrin, Raymond M. Everett, Jack H. Dean
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 18(4)
Ipazilide fumarate (Win 54,177-4) is a chemically novel antiarrhythmic agent that prolongs ventricular refractoriness and possesses antiectopic activity. Subchronic (29 days) nonclinical safety evaluation of ipazilide was conducted following oral and