Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David J. Wynne"'
Autor:
Jommel Macaraeg, Isaac Reinhard, Matthew Ward, Danielle Carmeci, Madison Stanaway, Amy Moore, Ethan Hagmann, Katherine Brown, David J. Wynne
Publikováno v:
Biology Open, Vol 11, Iss 7 (2022)
Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the chromosomal passenger complex (CPC) to mitotic and meiotic chromosomes. Haspin remains less well studied than other M-phase kinases, and the models explainin
Externí odkaz:
https://doaj.org/article/a48db24ec5194adfb8a90537f5e50b22
Publikováno v:
PLoS Genetics, Vol 4, Iss 11 (2008)
Externí odkaz:
https://doaj.org/article/f6959bbc36274521902b0732dda64bed
Publikováno v:
PLoS Genetics, Vol 4, Iss 10, p e1000235 (2008)
Crossover recombination and the formation of chiasmata normally ensure the proper segregation of homologous chromosomes during the first meiotic division. zhp-3, the Caenorhabditis elegans ortholog of the budding yeast ZIP3 gene, is required for cros
Externí odkaz:
https://doaj.org/article/930fb69b24b64c1fa03c75788162115b
Autor:
Hironori Funabiki, David J. Wynne
Publikováno v:
Molecular Biology of the Cell
Superresolution fluorescence microscopy of vertebrate kinetochore proteins reveals that outer kinetochore components assume diverse distribution patterns, including a ring-like configuration encircling the CENP-A–marked centromeric chromatin on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a44c6f220d983b6d37a44b2c0fa3ab
https://doi.org/10.1091/mbc.e16-02-0130
https://doi.org/10.1091/mbc.e16-02-0130
Publikováno v:
Cold Spring Harb Protoc
The Xenopus egg extract system has been widely used to study cell cycle events, including DNA replication, nuclear envelope formation, spindle assembly, chromosome condensation and kinetochore formation. The functional roles of the proteins involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27524ee3873ca8973a59fb9fa4edfdaf
https://pubmed.ncbi.nlm.nih.gov/29382808
https://pubmed.ncbi.nlm.nih.gov/29382808
Autor:
David J. Wynne, Hironori Funabiki
Publikováno v:
The Journal of Cell Biology
A subset of inner and outer kinetochore proteins responsible for lateral attachment and spindle checkpoint signaling in Xenopus egg extracts collaboratively coalesce into micrometer-scale filamentous protrusions in the absence of microtubules.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fbbaaf83bc34483c4241e599878cc0
https://doi.org/10.1083/jcb.201506020
https://doi.org/10.1083/jcb.201506020
Autor:
Hironori Funabiki, David J. Wynne
Publikováno v:
Chromosoma. 122:135-158
The kinetochore, the proteinaceous structure on the mitotic centromere, functions as a mechanical latch that hooks onto microtubules to support directional movement of chromosomes. The structure also brings in a number of signaling molecules, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aede37b1d338c72c27e36b3cadaa6d4
https://doi.org/10.1007/s00412-013-0401-5
https://doi.org/10.1007/s00412-013-0401-5
Publikováno v:
The Journal of Cell Biology
The chromosomal passenger complex contributes to the activation of the mitotic checkpoint and is composed of INCENP, Survivin, Borealin, and the kinase Aurora B. Wheelock et al. define the role of the INCENP domains binding chromatin and microtubules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37b98b7b2f478eb06952cdf5f05b5e6
https://pubmed.ncbi.nlm.nih.gov/28314740
https://pubmed.ncbi.nlm.nih.gov/28314740
Publikováno v:
Cold Spring Harbor Protocols. 2018:pdb.prot097113
The Xenopus egg extract system has been widely used to study cell cycle events, including DNA replication, nuclear envelope formation, spindle assembly, chromosome condensation and kinetochore formation. The functional roles of the proteins involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ba092eac9aeeefd9ddc848d6f8d924d
https://doi.org/10.1101/pdb.prot097113
https://doi.org/10.1101/pdb.prot097113
Autor:
Roshni A. Kasad, Abby F. Dernburg, Regina Rillo, Peter M. Carlton, Berith Isaac, David J. Wynne, Aya Sato, Carolyn M. Phillips
Publikováno v:
Cell. 139(5):907-919
SummaryDuring meiosis, each chromosome must pair with its unique homologous partner, a process that usually culminates with the formation of the synaptonemal complex (SC). In the nematode Caenorhabditis elegans, special regions on each chromosome kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4426d56932b0999c7ab7d9efb8939e28