Discovery of rare, diagnostic AluYb8/9 elements in diverse human populations

Autor: Julie Feusier, David J. Witherspoon, W. Scott Watkins, Clément Goubert, Thomas A. Sasani, Lynn B. Jorde

Publikováno v: Mobile DNA, Vol 8, Iss 1, Pp 1-10 (2017)

Abstract Background Polymorphic human Alu elements are excellent tools for assessing population structure, and new retrotransposition events can contribute to disease. Next-generation sequencing has greatly increased the potential to discover Alu ele

Externí odkaz: https://doaj.org/article/046ccbb1e3264f1ba464b90929820dbd

Ancestry of the Iban is predominantly Southeast Asian: genetic evidence from autosomal, mitochondrial, and Y chromosomes.

Autor: Tatum S Simonson, Jinchuan Xing, Robert Barrett, Edward Jerah, Peter Loa, Yuhua Zhang, W Scott Watkins, David J Witherspoon, Chad D Huff, Scott Woodward, Bryan Mowry, Lynn B Jorde

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16338 (2011)

Humans reached present-day Island Southeast Asia (ISEA) in one of the first major human migrations out of Africa. Population movements in the millennia following this initial settlement are thought to have greatly influenced the genetic makeup of cur

Externí odkaz: https://doaj.org/article/6c497f47d08b4295941640db01bce23a

Adaptive genetic changes related to haemoglobin concentration in native high-altitude Tibetans

Autor: Chad Huff, Lynn B. Jorde, Josef T. Prchal, Tatum S. Simonson, David J. Witherspoon

Publikováno v: Experimental Physiology. 100:1263-1268

What is the topic of this review? Tibetans have genetic adaptations that are hypothesized to underlie the distinct set of traits they exhibit at altitude. What advances does it highlight? Several adaptive signatures in the same genomic regions have b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5951ee3fa98ed8e6c94b55c0ea471fb9
https://doi.org/10.1113/ep085035

The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth

Autor: Alan R. Rogers, Michael W. Varner, Lynn B. Jorde, Wilfred Wu, M. Sean Esplin, Tracy A. Manuck, Gregory J. Stoddard, Erin A.S. Clark, Ken R. Smith, David J. Witherspoon, Alison Fraser, Karin Chen

Publikováno v: Human Genetics. 134:803-808

Preterm birth (PTB), defined as birth prior to a gestational age (GA) of 37 completed weeks, affects more than 10% of births worldwide. PTB is the leading cause of neonatal mortality and is associated with a broad spectrum of lifelong morbidity in su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1c19cee79307b36cbbf7f1196ec9bbd
https://doi.org/10.1007/s00439-015-1558-1

The common marmoset genome provides insight into primate biology and evolution

Autor: San Juana Ruiz, Daniel Gerlach, Tomas Vinar, Brona Brejova, Saba Sajjadian, Miriam K. Konkel, Muthuswamy Raveendran, Yih Shin Liu, Paul Flicek, Lubomir Tomaska, Donna M. Muzny, Daniel R. Schrider, Megan C. Ranck, Kjersti Aagaard, Huyen Dinh, Jayantha B. Tennakoon, Lucinda Fulton, Lynne V. Nazareth, Brygg Ullmer, George M. Weinstock, Kim D. Delehaunty, Xose S. Puente, Charles E. Vejnar, Shyam Prabhakar, Matthew W. Hahn, J. Scott Moncrieff, Mark A. Batzer, Tina Graves, Catherine C. Fontenot, Carlos López-Otín, Corinna N. Ross, Catrina Fronick, Jeffrey Rogers, Nirmala Arul Rayan, Mario Ventura, Pieter J. De Jong, Elaine R. Mardis, Steve Searle, Christie LKovar, David Haig, Ngoc Nguyen, Shalini N. Jhangiani, Margaret Morgan, Crystal M. Warner, Mimi M. Chandrabose, Keith G. Mansfield, Vandita Joshi, Kathryn Beal, Saverio B. Capuano, Magali Ruffier, Ling Ling Pu, Jerilyn A. Walker, Marvin Diep Dao, John Lopez, Irene Newsham, Yuanqing Wu, Jan Hinnerk Vogel, Arian F.A. Smit, Javier Herrero, Andrew Cree, Tomas Marques-Bonet, Oronzo Capozzi, LaDeana W. Hillier, Robert S. Fulton, Claudio Casola, Mariano Rocchi, Benjamin Soibam, Suzette D. Tardif, Derek E. Wildman, Evgenia V. Kriventseva, Kim C. Worley, Baoli Zhu, Jennifer F. Hughes, Robert Hubley, Geoffrey Okwuonu, Jennifer Hume, Lora Lewis, Ricardo C.H. del Rosario, Devin P. Locke, Lora Perales, David Rio Deiros, David J. Witherspoon, Yi Han, Brian J. Raney, David Rodríguez, Stephen Fitzgerald, Jireh Santibanez, Albert J. Vilella, R. Gerald Fowler, Qing Wang, Belen Lorente-Galdos, Ramatu Ayiesha Gabisi, Víctor Quesada, Weimin Xiao, Nicoletta Archidiacono, Emre Karakor, Helen Skaletsky, R. Alan Harris, Evgeny M. Zdobnov, Richard A. Gibbs, Wesley C. Warren, Patrick Minx, Preethi H. Gunaratne, Rita A. Wright, Doriana Misceo, Jinchuan Xing, Evan E. Eichler, Lynn B. Jorde, Carolin Kosiol, Rick K. Wilson, Sandra L. Lee

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
Nature genetics
Nature Genetics, Vol. 46, No 8 (2014) pp. 850-857

The Marmoset Genome Sequencing and Analysis Consortium.-- Worley, Kim C. et al.
We report the whole-genome sequence of the common marmoset (Callithrix jacchus). The 2.26-Gb genome of a female marmoset was assembled using Sanger read data (6×) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fec5c449e4aa853bab51e38240f28b
https://doi.org/10.1038/ng.3042