Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David J. Weader"'
Autor:
Philip H. Abbosh, Wafik S. El-Deiry, Erica R. McKenzie, Ali Behbahani, Alexander L. Metz, David J. Weader, Robert N. Uzzo, Moataz Ellithi, Rahmat K. Sikder
Figure S3: SW780 and RT4 cells are sensitized to cisplatin after the loss of p21. SW780 sg12A clone is more sensitive to cisplatin than sg109A clone, whereas in RT4, the sg12A and sg109a clones have similar sensitivities to cisplatin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bbe1a67d85ee11ad8f93f529caee8d
https://doi.org/10.1158/1541-7786.22513659.v1
https://doi.org/10.1158/1541-7786.22513659.v1
Autor:
Philip H. Abbosh, Wafik S. El-Deiry, Erica R. McKenzie, Ali Behbahani, Alexander L. Metz, David J. Weader, Robert N. Uzzo, Moataz Ellithi, Rahmat K. Sikder
Figure S1. A. sg12 successfully edited the CDKN1A gene in SW780 with high efficiency; chromatogram shows deletion of an adenine (A). B. Histograms from TIDE analysis of single-cell clones showed that the clones have largely homogeneous populations. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d23031e9d849caade2e9b48314d380
https://doi.org/10.1158/1541-7786.22513662.v1
https://doi.org/10.1158/1541-7786.22513662.v1
Publikováno v:
Bladder Cancer. 6:471-479
BACKGROUND: Bladder cancer is one of the most common types of cancer diagnosed each year, and more than half of patients have non-muscle invasive bladder cancer (NMIBC). The standard of care for patients with high-grade NMIBC is Bacillus Calmette-Gue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74cb5b865e54215fc7d872ee590048d4
https://doi.org/10.3233/blc-200340
https://doi.org/10.3233/blc-200340
Autor:
David J. Weader, Alexander L. Metz, Robert N. Uzzo, Ali Behbahani, Wafik S. El-Deiry, Moataz Ellithi, Philip Abbosh, Rahmat K. Sikder, Erica R. McKenzie
Publikováno v:
Mol Cancer Res
Muscle-invasive bladder cancer (MIBC) frequently harbors mutations in the CDKN1A gene, which encodes the tumor suppressor protein p21, with the majority of alterations truncating the peptide. The effect of these mutations is poorly understood. We hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cdda2f31241a439bdbaf67a9f523a0
https://pubmed.ncbi.nlm.nih.gov/33272936
https://pubmed.ncbi.nlm.nih.gov/33272936
Autor:
David J. Weader, Marie R. Southerland, Wiley J. Youngs, Michael L. Stromyer, Abhishek Srivastava, Uttam Satyal, Philip Abbosh
Publikováno v:
Cancer Research. 80:6366-6366
Introduction: Intravesical therapy has critical role in the treatment of high-risk non-muscle invasive bladder cancer. Due to ongoing shortage of BCG and lack of effective alternatives, there is an urgent need for novel intravesical chemotherapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74538ec0ce3c828ea35db76940784e0a
https://doi.org/10.1158/1538-7445.am2020-6366
https://doi.org/10.1158/1538-7445.am2020-6366
Autor:
Philip Abbosh, Michael L. Stromyer, Wiley J. Youngs, Jessi A. Baughman, Marie R. Southerland, Uttam Satyal, Rahmat K. Sikder, David J. Weader
Publikováno v:
Eur J Med Chem
Imidazolium salts have shown great promise as anticancer materials. A new imidazolium salt (TPP1), with a triphenylphosphonium substituent, has been synthesized and evaluated for in vitro and in vivo cytotoxicity against bladder cancer. TPP1 was dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b6efacc099e401b346cd0a115153e9
https://doi.org/10.1016/j.ejmech.2019.111832
https://doi.org/10.1016/j.ejmech.2019.111832