Zobrazeno 1 - 10
of 38
pro vyhledávání: '"David J. Uhlinger"'
Autor:
Akiko Ishii-Watabe, Albert Torri, Rong Zeng, Daniel Kramer, Steven P. Piccoli, David J. Uhlinger, Stephanie Fraser, Patricia Siguenza, Afshin Safavi, John Smeraglia, Apollon Papadimitriou, Yan G. Ni, Susan M. Richards, Kyra J. Cowan, Alessandra Vitaliti, Lakshmi Amaravadi, Boris Gorovits, Gustavo Mendes Lima Santos, John Kadavil, Sam Haidar, Jan Welink, Yongchang Qiu, João Pedras-Vasconcelos, Chan C. Whiting, Li Xue, Christina Satterwhite, John Kamerud, Swati Gupta, Natasha Savoie, Herbert Birnboeck, Yoshiro Saito, Paul Rhyne, Fabrizio Galliccia, Laurent Cocea, Stephanie Croft, Bonnie Wu, Theingi M. Thway, Virginia Litwin, Corinna Krinos-Fiorotti, Darshana Jani, Charles S Hottenstein, Vinita Gupta, Roland F Staack, Fabio Garofolo, Eginhard Schick, Kara Scheibner, Meena Subramanyam, John Allinson, Renuka Pillutla, Robert Nelson, Flora Berisha, Martin Ullmann, Giane Sumner
Publikováno v:
Bioanalysis. 8:2475-2496
The 2016 10th Workshop on Recent Issues in Bioanalysis (10th WRIB) took place in Orlando, Florida with participation of close to 700 professionals from pharmaceutical/biopharmaceutical companies, biotechnology companies, contract research organizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a67282718390ee4d7f9eb9599bdcf67
https://doi.org/10.4155/bio-2016-4989
https://doi.org/10.4155/bio-2016-4989
Publikováno v:
Bioanalysis. 6:1049-1057
Background: Method developers of plate-based ligand-binding assays (LBAs) often face challenges establishing selectivity, specificity and range of quantitation to meet the needs of a particular study. Case studies are presented to compare different l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c025d5a791ea76bff1db740bf9f62d0e
https://doi.org/10.4155/bio.14.60
https://doi.org/10.4155/bio.14.60
Publikováno v:
Neuroscience Letters. 315:159-163
It has been shown that phospholipase D (PLD) activity is stimulated by the β-amyloid protein in neuronal cells. The aim of this study was to determine whether overexpression of the amyloid precursor protein (APP) affects the activity and the level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1703ab59906a8d580a9d11bd7a11fcfe
https://doi.org/10.1016/s0304-3940(01)02339-4
https://doi.org/10.1016/s0304-3940(01)02339-4
Autor:
Jill M. Carton, Dennis C. Argentieri, Bruce P. Damiano, Michael R. D'Andrea, David J. Uhlinger
Publikováno v:
Thrombosis and Haemostasis. 86:1320-1326
SummaryThe response to vascular injury is a complex wound healing response involving cell proliferation, migration, remodeling and inflammation. In the present studies we employed a rat balloon angioplasty model of vascular injury to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5314b67e0932d8d036a38122f7e79a23
https://doi.org/10.1055/s-0037-1616067
https://doi.org/10.1055/s-0037-1616067
Publikováno v:
Experimental & Molecular Medicine. 32:170-177
Phospholipase D (PLD) is an enzyme involved in signal transduction and widely distributed in mammalian cells. The signal transduction pathways and role for phospholipid metabolism during hormonal response in cortical collecting duct remain partly und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d84b6b50c94ff77d0a968b0e4e67b3
https://doi.org/10.1038/emm.2000.28
https://doi.org/10.1038/emm.2000.28
Autor:
Jill M. Carton, David K. Perry, David J. Uhlinger, Yusuf A. Hannun, Amit K. Shah, Filmore I. Meredith
Publikováno v:
Journal of Biological Chemistry. 275:9078-9084
The de novo pathway of sphingolipid synthesis has been identified recently as a novel means of generating ceramide during apoptosis. Furthermore, it has been suggested that the activation of dihydroceramide synthase is responsible for increased ceram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221b623c826a36a22912c47bfbef6984
https://doi.org/10.1074/jbc.275.12.9078
https://doi.org/10.1074/jbc.275.12.9078
Autor:
David J. Uhlinger, Jong-Young Kwak
Publikováno v:
Biochemical and Biophysical Research Communications. 267:305-310
Agents which elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD) in human neutrophils. The PLD activity of human neutrophils requires protein factors in both membrane and cytosolic fractions. We have studied the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52236574d756b722dd339012247b36c5
https://doi.org/10.1006/bbrc.1999.1941
https://doi.org/10.1006/bbrc.1999.1941
Publikováno v:
Experimental & Molecular Medicine. 30:214-220
Human promyelocytic leukemia cells (HL-60) have been used as a model system in which to study the effects of protein phosphatase inhibitors on NADPH-oxidase activation. Since O2- is generated by NADPH-oxidase, we examined the effect of calyculin A pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8520e68b76f06ee581d47542d3c607
https://doi.org/10.1038/emm.1998.31
https://doi.org/10.1038/emm.1998.31
Autor:
Minoru Tamura, Kenichi Ogata, Masazumi Takeshita, David J. Uhlinger, Kazuei Igarashi, Naoya Nishimoto
Publikováno v:
Biochemical Journal. 313:549-554
Spermine, a cellular polyamine, down-regulates O2- generation in human neutrophils stimulated by receptor-linked agonist [Ogata, Tamura and Takeshita (1992) Biochem. Biophys. Res. Commun. 182, 20-26]. In this study, to elucidate the mechanism for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cf966ccf6c4f555ff6324b97f06a86
https://doi.org/10.1042/bj3130549
https://doi.org/10.1042/bj3130549
Autor:
Edward P. Bowman, Isabel Lopez, Jong-Young Kwak, J. David Lambeth, David K. Perry, David J. Uhlinger
Publikováno v:
Journal of Biological Chemistry. 270:2431-2434
Proteins in both the cytosol and plasma membrane are needed to reconstitute cell-free phospholipase D activity from phagocytes (Olson, S., Bowman, E. P., and Lambeth, J. D. (1991) J. Biol. Chem. 266, 17236-17242); membrane factors include a small GTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cbb84cc25f5231d21da494f3d7b989
https://doi.org/10.1074/jbc.270.6.2431
https://doi.org/10.1074/jbc.270.6.2431