Zobrazeno 1 - 10
of 56
pro vyhledávání: '"David J. Solecki"'
Autor:
Anna E. Pittman, David J. Solecki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Neural progenitors and their neuronal progeny are bathed in extrinsic signals that impact critical decisions like the mode of cell division, how long they should reside in specific neuronal laminae, when to differentiate, and the timing of migratory
Externí odkaz:
https://doaj.org/article/8a9d21c7c668463e986f1e268bc59f3f
Autor:
David J. Solecki
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Germinal niche interactions and their effect on developing neurons have become the subject of intense investigation. Dissecting the complex interplay of cell-extrinsic and cell-intrinsic factors at the heart of these interactions reveals the critical
Externí odkaz:
https://doaj.org/article/2a40353229de49d1ae32a2c98bae171c
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
In neural development, progenitors transition from a proliferative to a differentiated state. Here, the authors show that cerebellar granule neurons retract primary cilia as they exit their proliferative niche upon decreased ECM engagement, enabling
Externí odkaz:
https://doaj.org/article/1fe6fc11d7a34ad794d68ff2297a024d
Autor:
Niraj Trivedi, Daniel R. Stabley, Blake Cain, Danielle Howell, Christophe Laumonnerie, Joseph S. Ramahi, Jamshid Temirov, Ryan A. Kerekes, Phillip R. Gordon-Weeks, David J. Solecki
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Neuronal migration is vital for neuronal circuit morphogenesis and is thought to rely on microtubule-actomyosin crosstalk. Here, the authors use super-resolution imaging and the drebrin microtubule-actin crosslinking protein to show that microtubule-
Externí odkaz:
https://doaj.org/article/f84ca427585b4917a3f04e7904711de9
Seven in Absentia E3 Ubiquitin Ligases: Central Regulators of Neural Cell Fate and Neuronal Polarity
Autor:
Taren Ong, David J. Solecki
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
During neural development, neural precursors transition from a proliferative state within their germinal niches to a migratory state as they relocate to their final laminar positions. Transitions across these states are coupled with dynamic alteratio
Externí odkaz:
https://doaj.org/article/f656c882bb0b488e98691b3d0ca56828
Autor:
Christophe Laumonnerie, Maleelo Shamambo, Daniel R. Stabley, Tommy L. Lewis, Niraj Trivedi, Danielle Howell, David J Solecki
SummaryGerminal zone (GZ) exit is at the top of a cascade of events promoting the maturation of neurons and their assembly into neuronal circuits. Developing neurons and their progenitors must interpret varied niche signals like morphogens, guidance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6837c1aa108256b4a8d05eddd0fd92
https://doi.org/10.1101/2022.06.21.497057
https://doi.org/10.1101/2022.06.21.497057
Autor:
Shalini Singh, Danielle Howell, Niraj Trivedi, Ketty Kessler, Taren Ong, Pedro Rosmaninho, Alexandre ASF Raposo, Giles Robinson, Martine F Roussel, Diogo S Castro, David J Solecki
Publikováno v:
eLife, Vol 5 (2016)
In the developing mammalian brain, differentiating neurons mature morphologically via neuronal polarity programs. Despite discovery of polarity pathways acting concurrently with differentiation, it's unclear how neurons traverse complex polarity tran
Externí odkaz:
https://doaj.org/article/3bb669145045432da756e9696be49b66
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Evidence is lacking as to how developing neurons integrate mitogenic signals with microenvironment cues to control proliferation and differentiation. We determine that the Siah2 E3 ubiquitin ligase functions in a coincidence detection circuit linking