Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David J. Schnepple"'
Autor:
Amy M. Sainski, Gary D. Bren, Scott H. Kaufmann, David J. Schnepple, Sergey Trushin, Sekar Natesampillai, Brett D. Shepard, Alicia Algeciras-Schimnich, Xue W. Meng, Stacey A. Rizza, Nathan W. Cummins, Andrew D. Badley
Publikováno v:
Journal of Biological Chemistry. 286:35742-35754
Virus-host interactions are characterized by the selection of adaptive mechanisms by which to evade pathogenic and defense mechanisms, respectively. In primary T cells infected with HIV, HIV infection up-regulates TNF-related apoptosis inducing ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48124db53390c7021103f561a4374c4a
https://doi.org/10.1074/jbc.m111.274639
https://doi.org/10.1074/jbc.m111.274639
Autor:
David J. Schnepple, Alicia Algeciras-Schimnich, Gary D. Bren, Andrew D. Badley, Stacey R. Vlahakis, Sergey Trushin
Publikováno v:
Clinical Pharmacology & Therapeutics. 82:294-299
Human immunodeficiency virus (HIV) infection results in excessive apoptosis of infected and uninfected cells, mediated by host and viral factors present in plasma. As HIV protease inhibitors (PIs) have intrinsic antiapoptotic properties, we questione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf690c441dde9f00e69de35a0a652178
https://doi.org/10.1038/sj.clpt.6100140
https://doi.org/10.1038/sj.clpt.6100140
Publikováno v:
AIDS. 19:1125-1133
Background: Sensitivity towards apoptosis induced by ligation of the tumor necrosis factor family of death receptors is controlled in part by death receptor expression. Whereas cellular activation enhances Fas receptor expression and induces Fas sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d4b49288c6f26b05c1d967f24e4e65
https://doi.org/10.1097/01.aids.0000176212.16205.23
https://doi.org/10.1097/01.aids.0000176212.16205.23
Autor:
Vijay P. Singh, Andrew D. Badley, Rajinder K. Dawra, Sarah Navina, Stacey A. Rizza, Ashok K. Saluja, Suresh T. Chari, David J. Schnepple, Santhi Swaroop Vege, Alicia Algeciras-Schimnich, Gary D. Bren
There is no clinical treatment that reduces acinar injury during pancreatitis. Human immunodeficiency virus (HIV) protease inhibitors (PI), including nelfinavir (NFV) and ritonavir (RTV), may reduce the rate of pancreatitis in HIV-infected patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbe3ec4489aa5b230c95fdf5e0bb2c9
https://europepmc.org/articles/PMC2696210/
https://europepmc.org/articles/PMC2696210/
Autor:
Mona Loutfy, Sergey Trushin, Daniel C. Douek, Alicia Algeciras Schimnich, David J. Schnepple, Stacey R. Vlahakis, Jason M. Brenchley, Zilin Nie, Colin Kovacs, Gary D. Bren, Sarah E. Warren, Andrew D. Badley
Publikováno v:
Journal of virology. 81(13)
Human immunodeficiency virus type 1 (HIV-1) infection causes apoptosis of infected CD4 T cells as well as uninfected (bystander) CD4 and CD8 T cells. It remains unknown what signals cause infected cells to die. We demonstrate that HIV-1 protease spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c932ab0839f90f2d19eeb063b9bf8538
https://pubmed.ncbi.nlm.nih.gov/17442709
https://pubmed.ncbi.nlm.nih.gov/17442709
Autor:
Stacey R. Vlahakis, Andrew D. Badley, Sergey Trushin, Sarah E. Warren, David J. Schnepple, Alicia Algeciras-Schimnich, Gary D. Bren
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(8)
HIV-1 infection causes the depletion of host CD4 T cells through direct and indirect (bystander) mechanisms. Although HIV Env has been implicated in apoptosis of uninfected CD4 T cells via gp120 binding to either CD4 and/or the chemokine receptor 4 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783f4aa97585889786d186f918c48a8
https://pubmed.ncbi.nlm.nih.gov/17404265
https://pubmed.ncbi.nlm.nih.gov/17404265
Autor:
Dietlind L. Wahner-Roedler, Brent A. Bauer, Alexander G. Vandell, David J. Schnepple, Eric J. Buenz, Charles L. Howe
Publikováno v:
Journal of ethnopharmacology. 114(3)
Aim We previously reported significant antimicrobial activity against Gram-positive bacteria from the extract of the Atun tree ( Atuna racemosa ), identified through rapid digital bioprospecting of a 400-year-old historic herbal text. Toxicity studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abafede2e5bdfa890dd2e4de8b5ecf1
https://pubmed.ncbi.nlm.nih.gov/17889468
https://pubmed.ncbi.nlm.nih.gov/17889468
Autor:
Andrew D. Badley, David J. Schnepple
Publikováno v:
Cell Death During HIV Infection ISBN: 9780429122408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c4c49eb2d3203ab1f75a4737e295e1
https://doi.org/10.1201/9781420038156-29
https://doi.org/10.1201/9781420038156-29
Autor:
Brent A. Bauer, Timothy J. Motley, Eric J. Buenz, John M. Riddle, David J. Schnepple, Peter L. Elkin
Publikováno v:
Trends in pharmacological sciences. 25(9)
Ethnobotany has led to the identification of novel pharmacological agents but many challenges to using ethnobotany as a research tool remain. In particular, the loss of traditional knowledge together with the advent of high-throughput screening has m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d6b56fe4f83b2280ba782ca4ef0a66
https://pubmed.ncbi.nlm.nih.gov/15559252
https://pubmed.ncbi.nlm.nih.gov/15559252
Autor:
Andrew D. Badley, Julian J. Lum, David J. Schnepple, David H. Lynch, Georgina Mbisa, Nanci Hawley, Jennifer Mihowich, Zilin Nie, Jaime Sanchez-Dardon, John E. Kim, Shanil Narayan
The ability of interleukin-7 (IL-7) and IL-15 to expand and/or augment effector cell functions may be of therapeutic benefit to human immunodeficiency virus (HIV)-infected patients. The functional effects of these cytokines on innate HIV-specific imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc69cd898070605ad8423d4f43c1a6d
https://europepmc.org/articles/PMC415792/
https://europepmc.org/articles/PMC415792/